Hepatic Impairment Clinical Trials

STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS
LAST UPDATED
J
A Study of Apalutamide in Participants With Severe Hepatic Impairment Compared With Participants With Normal Hepatic Function
Recruiting
  • Hepatic Impairment
  • Orlando, Florida
  • +2 more
2021-12-02
Dec 2, 2021
T
A Study of Soticlestat in Adults With Liver Failure Compared to Those With Normal Liver Function
Recruiting
  • Hepatic Impairment
  • Healthy Volunteers
  • Hialeah, Florida
  • +2 more
2021-11-29
Nov 29, 2021
N
Pharmacokinetics Study of FIA586 in Participants With Mild and Moderate Hepatic Impairment
Not yet recruiting
  • Hepatic Impairment
  • (no location specified)
2021-11-30
Nov 30, 2021
A
Pharmacokinetics of Sotorasib in Healthy Participants and Participants With Moderate or Severe Hepatic Impairment
Recruiting
  • Hepatic Impairment
  • Tustin, California
  • +4 more
2021-11-29
Nov 29, 2021
A
A Study to Assess Zibotentan Pharmacokinetics in Participants With Moderate Hepatic and Moderate Renal Impairment
Recruiting
  • Hepatic Impairment
  • Renal Impairment
  • Sofia, Bulgaria
    Research Site
2021-11-26
Nov 26, 2021
G
A Single and Repeat Dose Trial in Participants With Hepatic Impairment
Recruiting
  • Hepatic Impairment
  • Sofia, Bulgaria
  • +1 more
2021-11-26
Nov 26, 2021
M
A Study to Evaluate the Effect of Mild, Moderate, and Severe Hepatic Impairment on Pharmacokinetics of Sitravatinib
Recruiting
  • Hepatic Impairment
  • Tustin, California
  • +4 more
2021-11-24
Nov 24, 2021
M
A Study to Investigate the Influence of Hepatic Impairment on MK-8189 Treatment (MK-8189-012)
Recruiting
  • Hepatic Impairment
  • Chula Vista, California
  • +1 more
2021-11-12
Nov 12, 2021
E
A Study of Oral Tazemetostat in Subjects With Moderate and Severe Hepatic Impairment With Advanced Malignancies
Recruiting
  • Hepatic Impairment
  • Advanced Malignant Solid Tumor
  • Chicago, Illinois
  • +12 more
2021-11-09
Nov 9, 2021
J
A Study to Evaluate the Effect of Hepatic Impairment on JNJ-42847922 in Adult Participants
Recruiting
  • Healthy
  • Hepatic Impairment
  • Kiel, Germany
  • +1 more
2021-11-11
Nov 11, 2021
N
Study to Assess the Pharmacokinetics of Pelacarsen (TQJ230) in Participants With Mild Hepatic Impairment Compared to Matched Healthy Participants
Not yet recruiting
  • Hepatic Impairment
  • (no location specified)
2021-11-09
Nov 9, 2021
G
A Single-dose, Open-label, Pharmacokinetic Study of Belapectin (GR-MD-02) in Subjects With Normal Hepatic Function and Subjects With Varying Degrees of Hepatic Impairment
Recruiting
  • Hepatic Impairment
  • Rialto, California
  • +3 more
2021-11-09
Nov 9, 2021
J
A Study to Evaluate the Effect of Hepatic Impairment on Lazertinib (JNJ-73841937)
Not yet recruiting
  • Hepatic Impairment
  • Healthy
  • Kiel, Germany
  • +1 more
2021-11-02
Nov 2, 2021
J
A Study of JNJ-53718678 in Participants With Hepatic Impairment
Recruiting
  • Hepatic Impairment
  • Orlando, Florida
  • +1 more
2021-11-03
Nov 3, 2021
B
A Single-dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of BMS-986263 in Participants With Varying Degrees of Liver Impairment - 2021
Completed
  • Hepatic Impairment
  • San Antonio, Texas
    The Texas Liver Institute
2021-10-29
Oct 29, 2021
J
An Investigational Study of SHR3680 in Participants With Mild to Moderate Liver Impairment and Healthy Participants
Recruiting
  • Hepatic Impairment
  • Healthy Participants
  • GuangZhou, Guangdong, China
    Guangzhou Eighth People'S Hospital
2021-11-02
Nov 2, 2021
A
A Study to Evaluate ASP0367 in Participants With Mild/Moderate Hepatic Impairment Compared to Participants With Normal Hepatic Function
Recruiting
  • Hepatic Impairment
  • Healthy Volunteers
  • San Antonio, Texas
    Texas Liver Institute
2021-11-02
Nov 2, 2021
Z
Hepatic Impairment With Cirrhosis Due to Cholestatic Liver Disease
Recruiting
  • Hepatic Impairment
  • +2 more
  • Saroglitazar Magnesium 1 mg
  • Saroglitazar Magnesium 2 mg
  • Indianapolis, Indiana
    Indiana University
2021-11-01
Nov 1, 2021
P
Clinical Pharmacokinetic Study of Lurbinectedin in Patients With Advanced Solid Tumors and Varying Degrees of Hepatic Impairment
Recruiting
  • Advanced Solid Tumor
  • Hepatic Impairment
  • Málaga, Andalucía, Spain
  • +5 more
2021-10-19
Oct 19, 2021
C
An Open-Label Study Following Oral Dosing of Seladelpar to Subjects With Primary Biliary Cholangitis (PBC) and Hepatic Impairment (HI)
Recruiting
  • Primary Biliary Cholangitis
  • +2 more
  • Seladelpar 10 mg
  • Seladelpar 10 mg or less
  • San Antonio, Texas
    American Research Corporation at the Texas Liver Institute
2021-10-19
Oct 19, 2021
P
Study to Estimate the Effects of Hepatic Impairment on the Pharmacokinetics (PK) of PF-07321332
Recruiting
  • Hepatic Impairment
  • Tustin, California
  • +1 more
2021-10-26
Oct 26, 2021
H
Surufatinib Hepatic Impairment Study - 2021
Completed
  • Hepatic Impairment
  • Tustin, California
  • +1 more
2021-10-20
Oct 20, 2021
N
Pharmacokinetic (PK) and Safety Study of Iptacopan (LNP023) in Participants With Mild, Moderate, and Severe Hepatic Impairment Compared to Matched Control Healthy Participants With Normal Hepatic Function.
Not yet recruiting
  • Hepatic Impairment
  • (no location specified)
2021-10-13
Oct 13, 2021
J
Pharmacokinetics and Safety of SHR0302 in Patients With Hepatic Impairment - 2020
Completed
  • Hepatic Impairment
  • Changchun, Jilin, China
    The First Affiliated Hospital of Jilin University
2021-10-13
Oct 13, 2021
S
Safety Study of Cenobamate in Subjects With Normal Hepatic Function and Subjects With Severe Hepatic Impairment
Recruiting
  • Hepatic Impairment
  • Wrocław, Poland
  • +1 more
2021-10-06
Oct 6, 2021