Hepatic Impairment Clinical Trials

STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS
LAST UPDATED
M
A Study to Evaluate the Effect of Mild, Moderate, and Severe Hepatic Impairment on Pharmacokinetics of Sitravatinib
Recruiting
  • Hepatic Impairment
  • Tustin, California
  • +4 more
2022-04-04
Apr 4, 2022
A
Pharmacokinetics of Sotorasib in Healthy Participants and Participants With Moderate or Severe Hepatic Impairment - 2022
Completed
  • Hepatic Impairment
  • Tustin, California
  • +4 more
2022-04-01
Apr 1, 2022
J
A Study to Evaluate the Effect of Hepatic Impairment on JNJ-42847922 in Adult Participants - 2021
Completed
  • Healthy
  • Hepatic Impairment
  • Kiel, Germany
  • +1 more
2022-03-30
Mar 30, 2022
G
A Single-dose, Open-label, Pharmacokinetic Study of Belapectin (GR-MD-02) in Subjects With Normal Hepatic Function and Subjects With Varying Degrees of Hepatic Impairment - 2022
Completed
  • Hepatic Impairment
  • Rialto, California
  • +3 more
2022-03-24
Mar 24, 2022
J
A Study of Apalutamide in Participants With Severe Hepatic Impairment Compared With Participants With Normal Hepatic Function
Recruiting
  • Hepatic Impairment
  • Orlando, Florida
  • +2 more
2022-03-24
Mar 24, 2022
J
A Study to Evaluate the Effect of Hepatic Impairment on Lazertinib (JNJ-73841937)
Recruiting
  • Hepatic Impairment
  • Healthy
  • Kiel, Germany
  • +1 more
2022-03-24
Mar 24, 2022
M
MDMA in Subjects With Moderate Hepatic Impairment and Subjects With Normal Hepatic Function
Not yet recruiting
  • Pharmacokinetics
  • Hepatic Impairment
  • Knoxville, Tennessee
    Alliance for Multispecialty Research, LLC.
2022-03-22
Mar 22, 2022
C
An Open-Label Study Following Oral Dosing of Seladelpar to Subjects With Primary Biliary Cholangitis (PBC) and Hepatic Impairment (HI)
Recruiting
  • Primary Biliary Cholangitis
  • +2 more
  • Seladelpar 10 mg
  • Seladelpar 10 mg or less
  • Sacramento, California
  • +5 more
2022-03-18
Mar 18, 2022
F
A Phase I Study to Assess the Pharmacokinetics of Olorofim in Subjects With Hepatic Impairment - 2021
Completed
  • Hepatic Impairment
  • Tustin, California
  • +1 more
2022-03-15
Mar 15, 2022
J
A Study of JNJ-53718678 in Participants With Hepatic Impairment
Recruiting
  • Hepatic Impairment
  • Orlando, Florida
  • +1 more
2022-03-15
Mar 15, 2022
M
A Study to Investigate the Influence of Hepatic Impairment on MK-8189 Treatment (MK-8189-012) - 2022
Completed
  • Hepatic Impairment
  • Chula Vista, California
  • +1 more
2022-03-08
Mar 8, 2022
K
KD025 Hepatic Impairment Study With Normal Hepatic Function and Subjects With Varying Degrees of Hepatic Impairment
Recruiting
  • Hepatic Impairment
  • Rialto, California
  • +4 more
2022-03-08
Mar 8, 2022
T
A Study of Soticlestat in Adults With Liver Failure Compared to Those With Normal Liver Function
Recruiting
  • Hepatic Impairment
  • Healthy Volunteers
  • Edgewater, Florida
  • +5 more
2022-03-03
Mar 3, 2022
A
A Study to Investigate the Effect of Mild and Moderate Hepatic Impairment on the Safety and Tolerability of Fezolinetant Compared to Participants With Normal Hepatic Function - 2021
Completed
  • Hepatic Impairment
  • Healthy Volunteers
  • Clearwater, Florida
  • +3 more
2022-03-02
Mar 2, 2022
I
A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics of a Single Dose of Cenerimod
Recruiting
  • Healthy
  • Hepatic Impairment
  • Porto, Portugal
    BlueClinical Phase 1 Hospital de Prelado
2022-02-25
Feb 25, 2022
H
Fruquintinib Hepatic Impairment Study
Not yet recruiting
  • Hepatic Impairment
  • (no location specified)
2022-02-08
Feb 8, 2022
M
Pharmacokinetics of TD-4208 in Patients With Moderate Hepatic Impairment - 2016
Completed
  • Hepatic Impairment
  • Orlando, Florida
    Orlando Clinical Research Center (OCRD)
2022-02-22
Feb 22, 2022
S
Safety Study of Cenobamate in Subjects With Normal Hepatic Function and Subjects With Severe Hepatic Impairment
Recruiting
  • Hepatic Impairment
  • Wrocław, Poland
  • +1 more
2022-02-16
Feb 16, 2022
G
A Single and Repeat Dose Trial in Participants With Hepatic Impairment
Recruiting
  • Hepatic Impairment
  • Sofia, Bulgaria
  • +3 more
2022-02-14
Feb 14, 2022
N
Pharmacokinetic (PK) and Safety Study of Iptacopan (LNP023) in Participants With Mild, Moderate, and Severe Hepatic Impairment Compared to Matched Control Healthy Participants With Normal Hepatic Function.
Recruiting
  • Hepatic Impairment
  • San Antonio, Texas
    Novartis Investigative Site
2022-02-07
Feb 7, 2022
E
Study to Evaluate the Pharmacokinetics (PK) of E7090 and Its Metabolite in Participants With Mild and Moderate Hepatic Impairment Compared to Healthy Participants
Recruiting
  • Hepatic Impairment
  • Yufu, Oita, Japan
  • +2 more
2022-01-25
Jan 25, 2022
A
A Study to Evaluate ASP0367 in Participants With Mild/Moderate Hepatic Impairment Compared to Participants With Normal Hepatic Function - 2022
Completed
  • Hepatic Impairment
  • Healthy Volunteers
  • Miami, Florida
  • +2 more
2022-02-04
Feb 4, 2022
C
Pharmacokinetics of Enasidenib (CC-90007) in Participants With Mild, Moderate and Severe Hepatic Impairment
Recruiting
  • Hepatic Impairment
  • Miami, Florida
  • +2 more
2022-02-02
Feb 2, 2022
A
A Study to Assess Zibotentan Pharmacokinetics in Participants With Moderate Hepatic and Moderate Renal Impairment - 2021
Completed
  • Hepatic Impairment
  • Renal Impairment
  • Sofia, Bulgaria
    Research Site
2022-01-26
Jan 26, 2022
P
Study to Estimate the Effects of Hepatic Impairment on the Pharmacokinetics (PK) of PF-07321332 - 2021
Completed
  • Hepatic Impairment
  • Tustin, California
  • +1 more
2022-01-18
Jan 18, 2022