Sickle Cell Disease

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STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS

Sickle Cell Disease Trial in Atlanta, Cincinnati (I-STRONG for SCD)

Recruiting
  • Sickle Cell Disease
  • I-STRONG for SCD
  • Atlanta, Georgia
  • +1 more
Oct 26, 2023

Sickle Cell Disease Trial in Atlanta (Etavopivat)

Not yet recruiting
  • Sickle Cell Disease
  • Atlanta, Georgia
    Emory University Children's Healthcare of Atlanta
Feb 10, 2023

Sickle Cell Disease Trial in Boston (Autologous CD34+ HSC cells transduced with the lentiviral vector containing a shRNA

Recruiting
  • Sickle Cell Disease
  • Autologous CD34+ HSC cells transduced with the lentiviral vector containing a shRNA targeting BCL11a
  • Los Angeles, California
  • +8 more
Jan 10, 2023

Sickle Cell Disease, Hemoglobinopathies Trial in Canada, United States (EDIT-301)

Recruiting
  • Sickle Cell Disease
  • Hemoglobinopathies
  • EDIT-301
  • Oakland, California
  • +18 more
Jan 10, 2023

Healthy Adult Subjects, Sickle Cell Disease Trial in Little Rock, Atlanta, Overland Park (FTX-6058/ oral capsule(s), FTX-6058 -

Completed
  • Healthy Adult Subjects
  • Sickle Cell Disease
  • FTX-6058/placebo oral capsule(s)
  • +2 more
  • Atlanta, Georgia
  • +1 more
Dec 9, 2022

Sickle Cell Disease Trial in United States (Hematopoietic Stem Cell Transplantation)

Completed
  • Sickle Cell Disease
  • Hematopoietic Stem Cell Transplantation
  • Birmingham, Alabama
  • +18 more
Dec 7, 2022

Sickle Cell Disease Treated With Ex Vivo Gene Therapy

Enrolling by invitation
  • Sickle Cell Disease
  • Safety and efficacy assessments
  • Birmingham, Alabama
  • +11 more
Oct 31, 2022

Sickle Cell Disease Trial in Worldwide (Etavopivat Tablets, Placebo Tablets)

Recruiting
  • Sickle Cell Disease
  • Etavopivat Tablets Low dose
  • +3 more
  • Birmingham, Alabama
  • +77 more
Oct 11, 2022

Sickle Cell Disease Trial in Worldwide (Voxelotor)

Active, not recruiting
  • Sickle Cell Disease
  • Little Rock, Arkansas
  • +47 more
Sep 28, 2022

Sickle Cell Disease Trial in Lebanon, United Kingdom, United States (Voxelotor)

Enrolling by invitation
  • Sickle Cell Disease
  • Washington, District of Columbia
  • +10 more
Sep 27, 2022

Sickle Cell Disease Trial in United States (Busulfan, Fludarabine, r-ATG)

Active, not recruiting
  • Sickle Cell Disease
  • Oakland, California
  • +34 more
Sep 21, 2022

Sickle Cell Disease Trial in United States (biological, drug, genetic)

Recruiting
  • Sickle Cell Disease
  • Plerixafor
  • +2 more
  • Oakland, California
  • +5 more
Sep 13, 2022

Sickle Cell Disease Trial in Atlanta (procedure, drug, other, radiation)

Recruiting
  • Sickle Cell Disease
  • Bone Marrow Transplant (BMT)
  • +7 more
  • Atlanta, Georgia
    Children's Healthcare of Atlanta
Sep 13, 2022

Sickle Cell Disease Trial in Syracuse (Low Dose Rifaximin ER, Low Dose Rifaximin DER, High Dose Rifaximin ER)

Recruiting
  • Sickle Cell Disease
  • Low Dose Rifaximin ER
  • +4 more
  • Atlanta, Georgia
  • +1 more
Aug 29, 2022

Sickle Cell Disease Trial in France, United Kingdom, United States (Red Blood Cell, Standard of care)

Recruiting
  • Sickle Cell Disease
  • Red Blood Cell
  • Standard of care
  • Tuscaloosa, Alabama
  • +19 more
Aug 23, 2022

Sickle Cell Disease Trial in Atlanta (GBT021601)

Active, not recruiting
  • Sickle Cell Disease
  • Atlanta, Georgia
  • +1 more
Aug 10, 2022

SCD Curative Therapies

Not yet recruiting
  • Sickle Cell Disease
  • +3 more
    • Washington, District of Columbia
    • +4 more
    Jun 28, 2022

    Sickle Cell Disease Trial in Worldwide (IMR-687, Placebo)

    Terminated
    • Sickle Cell Disease
    • Birmingham, Alabama
    • +48 more
    May 9, 2022

    Sickle Cell Disease Trial in Atlanta (Arginine, Arginine (Loading), Arginine (Continuous))

    Recruiting
    • Sickle Cell Disease
    • Atlanta, Georgia
    • +1 more
    Apr 22, 2022

    Sickle Cell Disease Trial in Atlanta, Chapel Hill, Milwaukee (Transfusion)

    Recruiting
    • Sickle Cell Disease
    • Transfusion
    • Atlanta, Georgia
    • +2 more
    Feb 28, 2022

    Sickle Cell Disease Trial in United States (Provider-level intervention, Patient-level intervention)

    Active, not recruiting
    • Sickle Cell Disease
    • Provider-level intervention
    • Patient-level intervention
    • Little Rock, Arkansas
    • +14 more
    Feb 24, 2022

    Sickle Cell Disease Trial in Lebanon, United Kingdom, United States (Voxelotor)

    Recruiting
    • Sickle Cell Disease
    • Oakland, California
    • +17 more
    Jan 13, 2022

    Sickle Cell Disease Trial in United States (procedure, drug, radiation)

    Recruiting
    • Sickle Cell Disease
    • Haploidentical Bone Marrow Transplantation
    • +7 more
    • Birmingham, Alabama
    • +31 more
    Dec 30, 2021

    Sickle Cell Disease Trial in United States (Arginine Hydrochloride, Normal saline)

    Recruiting
    • Sickle Cell Disease
    • Arginine Hydrochloride
    • Normal saline
    • Los Angeles, California
    • +9 more
    Jan 12, 2022