Sickle Cell Disease

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STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS

Sickle Cell Disease Trial in Adana, Mersin (NDec - oral decitabine-tetrahydrouridine, HU - Hydroxyurea, Placebo)

Recruiting
  • Sickle Cell Disease
  • NDec - oral decitabine-tetrahydrouridine
  • +2 more
  • Oakland, California
  • +39 more
Jan 24, 2023

Sickle Cell Disease Trial in Worldwide (VIT-2763 120 mg, VIT-2763 360 mg, VIT-2763 240 mg)

Recruiting
  • Sickle Cell Disease
  • VIT-2763 120 mg
  • +4 more
  • Birmingham, Alabama
  • +12 more
Jan 20, 2023

Sickle Cell Disease Trial in Boston (Autologous CD34+ HSC cells transduced with the lentiviral vector containing a shRNA

Recruiting
  • Sickle Cell Disease
  • Autologous CD34+ HSC cells transduced with the lentiviral vector containing a shRNA targeting BCL11a
  • Los Angeles, California
  • +8 more
Jan 10, 2023

Sickle Cell Disease, Hemoglobinopathies Trial in Canada, United States (EDIT-301)

Recruiting
  • Sickle Cell Disease
  • Hemoglobinopathies
  • EDIT-301
  • Oakland, California
  • +18 more
Jan 10, 2023

Sickle Cell Disease Trial in Italy, United States (OTQ923, HIX763, OTQ923 or HIX763)

Recruiting
  • Sickle Cell Disease
  • OTQ923
  • Los Angeles, California
  • +4 more
Jan 9, 2023

Sickle Cell Disease Trial in United States (Hematopoietic Stem Cell Transplantation)

Completed
  • Sickle Cell Disease
  • Hematopoietic Stem Cell Transplantation
  • Birmingham, Alabama
  • +18 more
Dec 7, 2022

Sickle Cell Disease Treated With Ex Vivo Gene Therapy

Enrolling by invitation
  • Sickle Cell Disease
  • Safety and efficacy assessments
  • Birmingham, Alabama
  • +11 more
Oct 31, 2022

Sickle Cell Disease, Genetic Disease, Hematologic Diseases Trial in United States (Electronic Health Record (EHR) Embedded

Completed
  • Sickle Cell Disease
  • +3 more
  • Electronic Health Record (EHR) Embedded Individualized Pain Plan (IPP)
  • Oakland, California
  • +7 more
Oct 26, 2022

Sickle Cell Disease Trial in Netherlands, United Kingdom, United States (CSL889)

Recruiting
  • Sickle Cell Disease
  • CSL889
  • Chicago, Illinois
  • +12 more
Oct 11, 2022

Sickle Cell Disease Trial in Worldwide (Etavopivat Tablets, Placebo Tablets)

Recruiting
  • Sickle Cell Disease
  • Etavopivat Tablets Low dose
  • +3 more
  • Birmingham, Alabama
  • +77 more
Oct 11, 2022

Sickle Cell Disease Trial in Worldwide (Voxelotor)

Active, not recruiting
  • Sickle Cell Disease
  • Little Rock, Arkansas
  • +47 more
Sep 28, 2022

Sickle Cell Disease Trial in Lebanon, United Kingdom, United States (Voxelotor)

Enrolling by invitation
  • Sickle Cell Disease
  • Washington, District of Columbia
  • +10 more
Sep 27, 2022

Sickle Cell Disease Trial in United States (CD34 selected T-cell depleted allogeneic SCT)

Active, not recruiting
  • Sickle Cell Disease
  • CD34 selected T-cell depleted allogeneic SCT
  • Los Angeles, California
  • +5 more
Sep 27, 2022

Sickle Cell Disease Trial in United States (InCharge Health mobile application, HU Toolbox mobile application)

Completed
  • Sickle Cell Disease
  • InCharge Health mobile application
  • HU Toolbox mobile application
  • Augusta, Georgia
  • +6 more
Sep 26, 2022

Sickle Cell Disease Trial in France, United Kingdom, United States (Red Blood Cell, Standard of care)

Recruiting
  • Sickle Cell Disease
  • Red Blood Cell
  • Standard of care
  • Tuscaloosa, Alabama
  • +19 more
Aug 23, 2022

The Predictive Capacity of Machine Learning Models for

Recruiting
  • Sickle Cell Disease
  • Kidney Diseases, Chronic
  • Biospecimen/DNA collection and analysis
  • Chicago, Illinois
  • +2 more
Jul 14, 2022

Sickle Cell Disease, Sickle Cell Nephropathy Trial in Chicago (Voxelotor)

Recruiting
  • Sickle Cell Disease
  • Sickle Cell Nephropathy
  • Chicago, Illinois
    University of Illinois
Jun 16, 2022

Sickle Cell Disease Trial in Chicago (aß+ T-cell depletion with Miltenyi CliniMACS system)

Recruiting
  • Sickle Cell Disease
  • αβ+ T-cell depletion with Miltenyi CliniMACS system
  • Chicago, Illinois
    The University of Chicago
May 13, 2022

Sickle Cell Disease Trial in Worldwide (IMR-687, Placebo)

Terminated
  • Sickle Cell Disease
  • Birmingham, Alabama
  • +48 more
May 9, 2022

Sickle Cell Disease Trial in United Kingdom, United States (IMR-687, Placebo)

Completed
  • Sickle Cell Disease
  • Oakland, California
  • +12 more
Mar 22, 2022

Sickle Cell Disease Trial in Chicago (Nicotinamide)

Recruiting
  • Sickle Cell Disease
  • Chicago, Illinois
    University of Illinois at Chicago College of Medicine
Mar 21, 2022

Sickle Cell Disease, Sickle Beta Zero Thalassemia, Sickle B+ Thalassemia Trial in Chicago (MED-Go App)

Recruiting
  • Sickle Cell Disease
  • +3 more
  • MED-Go App
  • Chicago, Illinois
    Ann & Robert H Lurie Children's Hospital of Chicago
Mar 7, 2022

Sickle Cell Disease Trial in Canada, United States (Alemtuzumab intravenously, low dose total body irradiation, Sirolimus)

Recruiting
  • Sickle Cell Disease
  • Alemtuzumab intravenously, low dose total body irradiation, Sirolimus
  • Washington, District of Columbia
  • +5 more
Mar 2, 2022