Sickle Cell Disease
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Sickle Cell Disease Trial in Adana, Mersin (NDec - oral decitabine-tetrahydrouridine, HU - Hydroxyurea, Placebo)
Recruiting
- Sickle Cell Disease
- NDec - oral decitabine-tetrahydrouridine
- +2 more
-
Oakland, California
- +39 more
Jan 24, 2023
Sickle Cell Disease Trial in Boston (Autologous CD34+ HSC cells transduced with the lentiviral vector containing a shRNA
Recruiting
- Sickle Cell Disease
- Autologous CD34+ HSC cells transduced with the lentiviral vector containing a shRNA targeting BCL11a
-
Los Angeles, California
- +8 more
Jan 10, 2023
Sickle Cell Disease, Hemoglobinopathies Trial in Canada, United States (EDIT-301)
Recruiting
- Sickle Cell Disease
- Hemoglobinopathies
- EDIT-301
-
Oakland, California
- +18 more
Jan 10, 2023
Sickle Cell Disease Treated With Ex Vivo Gene Therapy
Enrolling by invitation
- Sickle Cell Disease
- Safety and efficacy assessments
-
Birmingham, Alabama
- +11 more
Oct 31, 2022
Sickle Cell Disease, Genetic Disease, Hematologic Diseases Trial in United States (Electronic Health Record (EHR) Embedded
Completed
- Sickle Cell Disease
- +3 more
- Electronic Health Record (EHR) Embedded Individualized Pain Plan (IPP)
-
Oakland, California
- +7 more
Oct 26, 2022
Sickle Cell Disease Trial in Worldwide (Etavopivat Tablets, Placebo Tablets)
Recruiting
- Sickle Cell Disease
- Etavopivat Tablets Low dose
- +3 more
-
Birmingham, Alabama
- +77 more
Oct 11, 2022
Sickle Cell Disease Trial in United States (CD34 selected T-cell depleted allogeneic SCT)
Active, not recruiting
- Sickle Cell Disease
- CD34 selected T-cell depleted allogeneic SCT
-
Los Angeles, California
- +5 more
Sep 27, 2022
Sickle Cell Disease Trial in United States (Busulfan, Fludarabine, r-ATG)
Active, not recruiting
- Sickle Cell Disease
- Busulfan
- +11 more
-
Oakland, California
- +34 more
Sep 21, 2022
Sickle Cell Disease Trial in United States (biological, drug, genetic)
Recruiting
- Sickle Cell Disease
- Plerixafor
- +2 more
-
Oakland, California
- +5 more
Sep 13, 2022
Sickle Cell Disease Trial in France, United Kingdom, United States (Red Blood Cell, Standard of care)
Recruiting
- Sickle Cell Disease
- Red Blood Cell
- Standard of care
-
Tuscaloosa, Alabama
- +19 more
Aug 23, 2022
Red Blood Cell - IMProving trAnsfusions for Chronically
Recruiting
- Sickle Cell Disease
- +2 more
- Red Blood Cell (RBC) Transfusion
-
Oakland, California
- +13 more
Mar 18, 2022
Sickle Cell Disease Trial in United States (Provider-level intervention, Patient-level intervention)
Active, not recruiting
- Sickle Cell Disease
- Provider-level intervention
- Patient-level intervention
-
Little Rock, Arkansas
- +14 more
Feb 24, 2022
Sickle Cell Disease Trial in United States (procedure, drug, radiation)
Recruiting
- Sickle Cell Disease
- Haploidentical Bone Marrow Transplantation
- +7 more
-
Birmingham, Alabama
- +31 more
Dec 30, 2021
Sickle Cell Disease Trial in United States (bb1111)
Active, not recruiting
- Sickle Cell Disease
- bb1111
-
Birmingham, Alabama
- +10 more
Dec 9, 2021
Iron Overload, Sickle Cell Disease, Other Anemias Trial in Worldwide (Deferiprone, Deferoxamine)
Terminated
- Iron Overload
- +2 more
-
Oakland, California
- +32 more
Jul 16, 2021
Pulmonary Hypertension, Sickle Cell Disease, Thalassemia Trial in Oakland (L-Glutamine)
Completed
- Pulmonary Hypertension
- +2 more
-
Oakland, CaliforniaChildren's Hospital & Research Center Oakland
Jun 8, 2021
Sickle Cell Disease, Vaso-Occlusive Crisis Trial in Oakland (Ketamine)
Completed
- Sickle Cell Disease
- Vaso-Occlusive Crisis
-
Oakland, CaliforniaUCSF Benioff Children's Hospital and Research Center Oakland
Mar 25, 2021
Sickle Cell Disease Trial in Worldwide (voxelotor, Placebo)
Multi-Center Study of Iron Overload: Pilot Study
Completed
- Sickle Cell Disease
- +2 more
-
Oakland, California
- +2 more
Sep 22, 2020
Multi-Center Study of Iron Overload: Survey Study (MCSIO)
Completed
- Sickle Cell Disease
- +2 more
-
Oakland, California
- +7 more
Sep 22, 2020