Sickle Cell Disease

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STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS

Sickle Cell Disease Trial in Adana, Mersin (NDec - oral decitabine-tetrahydrouridine, HU - Hydroxyurea, Placebo)

Recruiting
  • Sickle Cell Disease
  • NDec - oral decitabine-tetrahydrouridine
  • +2 more
  • Oakland, California
  • +39 more
Jan 24, 2023

Sickle Cell Disease Trial in Boston (Autologous CD34+ HSC cells transduced with the lentiviral vector containing a shRNA

Recruiting
  • Sickle Cell Disease
  • Autologous CD34+ HSC cells transduced with the lentiviral vector containing a shRNA targeting BCL11a
  • Los Angeles, California
  • +8 more
Jan 10, 2023

Sickle Cell Disease, Hemoglobinopathies Trial in Canada, United States (EDIT-301)

Recruiting
  • Sickle Cell Disease
  • Hemoglobinopathies
  • EDIT-301
  • Oakland, California
  • +18 more
Jan 10, 2023

Sickle Cell Disease Treated With Ex Vivo Gene Therapy

Enrolling by invitation
  • Sickle Cell Disease
  • Safety and efficacy assessments
  • Birmingham, Alabama
  • +11 more
Oct 31, 2022

Sickle Cell Disease, Genetic Disease, Hematologic Diseases Trial in United States (Electronic Health Record (EHR) Embedded

Completed
  • Sickle Cell Disease
  • +3 more
  • Electronic Health Record (EHR) Embedded Individualized Pain Plan (IPP)
  • Oakland, California
  • +7 more
Oct 26, 2022

Sickle Cell Disease Trial in Worldwide (Etavopivat Tablets, Placebo Tablets)

Recruiting
  • Sickle Cell Disease
  • Etavopivat Tablets Low dose
  • +3 more
  • Birmingham, Alabama
  • +77 more
Oct 11, 2022

Sickle Cell Disease Trial in Worldwide (Voxelotor)

Active, not recruiting
  • Sickle Cell Disease
  • Little Rock, Arkansas
  • +47 more
Sep 28, 2022

Sickle Cell Disease Trial in United States (CD34 selected T-cell depleted allogeneic SCT)

Active, not recruiting
  • Sickle Cell Disease
  • CD34 selected T-cell depleted allogeneic SCT
  • Los Angeles, California
  • +5 more
Sep 27, 2022

Sickle Cell Disease Trial in United States (Busulfan, Fludarabine, r-ATG)

Active, not recruiting
  • Sickle Cell Disease
  • Oakland, California
  • +34 more
Sep 21, 2022

Sickle Cell Disease Trial in United States (biological, drug, genetic)

Recruiting
  • Sickle Cell Disease
  • Plerixafor
  • +2 more
  • Oakland, California
  • +5 more
Sep 13, 2022

Sickle Cell Disease Trial in France, United Kingdom, United States (Red Blood Cell, Standard of care)

Recruiting
  • Sickle Cell Disease
  • Red Blood Cell
  • Standard of care
  • Tuscaloosa, Alabama
  • +19 more
Aug 23, 2022

Sickle Cell Disease Trial in Los Angeles, Oakland (CRISPR_SCD001)

Not yet recruiting
  • Sickle Cell Disease
  • Los Angeles, California
  • +1 more
Apr 25, 2022

Sickle Cell Disease Trial in United Kingdom, United States (IMR-687, Placebo)

Completed
  • Sickle Cell Disease
  • Oakland, California
  • +12 more
Mar 22, 2022

Red Blood Cell - IMProving trAnsfusions for Chronically

Recruiting
  • Sickle Cell Disease
  • +2 more
  • Red Blood Cell (RBC) Transfusion
  • Oakland, California
  • +13 more
Mar 18, 2022

Sickle Cell Disease Trial in United States (Provider-level intervention, Patient-level intervention)

Active, not recruiting
  • Sickle Cell Disease
  • Provider-level intervention
  • Patient-level intervention
  • Little Rock, Arkansas
  • +14 more
Feb 24, 2022

Sickle Cell Disease Trial in Lebanon, United Kingdom, United States (Voxelotor)

Recruiting
  • Sickle Cell Disease
  • Oakland, California
  • +17 more
Jan 13, 2022

Sickle Cell Disease Trial in United States (procedure, drug, radiation)

Recruiting
  • Sickle Cell Disease
  • Haploidentical Bone Marrow Transplantation
  • +7 more
  • Birmingham, Alabama
  • +31 more
Dec 30, 2021

Sickle Cell Disease Trial in United States (bb1111)

Active, not recruiting
  • Sickle Cell Disease
  • bb1111
  • Birmingham, Alabama
  • +10 more
Dec 9, 2021

Pulmonary Hypertension, Sickle Cell Disease, Thalassemia Trial in Oakland (L-Glutamine)

Completed
  • Pulmonary Hypertension
  • +2 more
  • Oakland, California
    Children's Hospital & Research Center Oakland
Jun 8, 2021

Sickle Cell Disease, Vaso-Occlusive Crisis Trial in Oakland (Ketamine)

Completed
  • Sickle Cell Disease
  • Vaso-Occlusive Crisis
  • Oakland, California
    UCSF Benioff Children's Hospital and Research Center Oakland
Mar 25, 2021

Sickle Cell Disease Trial in Worldwide (voxelotor, Placebo)

Completed
  • Sickle Cell Disease
  • Birmingham, Alabama
  • +61 more
Jan 5, 2021

Multi-Center Study of Iron Overload: Pilot Study

Completed
  • Sickle Cell Disease
  • +2 more
    • Oakland, California
    • +2 more
    Sep 22, 2020

    Multi-Center Study of Iron Overload: Survey Study (MCSIO)

    Completed
    • Sickle Cell Disease
    • +2 more
      • Oakland, California
      • +7 more
      Sep 22, 2020