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Dacarbazine

Dacarbazine is a drug used to treat Melanoma, Lymphoma, Hodgkin Lymphoma, and other conditions. Dacarbazine is being actively studied in 39 studies and prior, has been studied in 60.

Top SponsorsTop SitesTop Investigators
Bristol-Myers SquibbMemorial Sloan Kettering Cancer CenterChristine Mauz-Korholz
National Cancer Institute (NCI)University of Michigan Comprehensive Cancer CenterProf. Dr. Peter Borchmann
AstraZenecaBeth Israel Deaconess Medical CenterGALIA AVRAHAMI
STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS
LAST UPDATED
U
Doxorubicin Hydrochloride, Pembrolizumab, Vinblastine, and Dacarbazine in Treating Patients With Classical Hodgkin Lymphoma
Recruiting
  • Classical Hodgkin Lymphoma
  • Dacarbazine
  • +4 more
  • Seattle, Washington
    Fred Hutch/University of Washington Cancer Consortium
2022-03-10
Mar 10, 2022
N
Fotemustine and Dacarbazine Versus Dacarbazine +/- Alpha Interferon in Advanced Malignant Melanoma - 2011
Completed
Has Results
  • Malignant Melanoma
  • Recurrent Melanoma
  • Dacarbazine
  • +2 more
  • (no location specified)
2020-10-18
Oct 18, 2020
P
A Study of Unesbulin (PTC596) in Combination With Dacarbazine in Participants With Advanced Leiomyosarcoma (LMS)
Recruiting
  • Leiomyosarcoma
  • Jacksonville, Florida
  • +4 more
2022-03-14
Mar 14, 2022
S
CytoreductiveSurgery & HIPEC w/Gemcitabine+Chemotherapy w/Dacarbazine in Uterine Leiomyosarcoma
Recruiting
  • LMS - Leiomyosarcoma
  • Uterine Leiomyosarcoma
  • Stanford, California
    Stanford University
2022-02-11
Feb 11, 2022
P
A Study of Unesbulin in Participants With Advanced Leiomyosarcoma (LMS)
Not yet recruiting
  • Leiomyosarcoma
  • (no location specified)
2022-02-25
Feb 25, 2022
I
Study With Trabectedin Versus Adriamycin Plus Dacarbazine, in Patients With Advanced Solitary Fibrous Tumor
Recruiting
  • Solitary Fibrous Tumors
  • Prato, Firenze, Italy
  • +5 more
2021-10-29
Oct 29, 2021
T
A Study of Brentuximab Vedotin + Adriamycin, Vinblastine, and Dacarbazine in Pediatric Participants With Advanced Stage Newly Diagnosed Hodgkin Lymphoma - 2021
Completed
Has Results
  • Hodgkin Disease
  • Brentuximab vedotin
  • +3 more
  • Aurora, Colorado
  • +13 more
2021-10-01
Oct 1, 2021
B
A Comparative Study in Chinese Subjects With Chemotherapy Naïve Stage IV Melanoma Receiving Ipilimumab (3 mg/kg) vs. Dacarbazine - 2019
Completed
Has Results
  • Melanoma
  • Nanjing, Jiangsu, China
  • +7 more
2020-05-05
May 5, 2020
C
Sodium Stibogluconate and IFNa-2b Followed By CDDP, VLB and DTIC Treating Pts.With Advanced Melanoma or Other Cancers - 2012
Completed
  • Stage IV Melanoma
  • recombinant interferon alfa-2b
  • +4 more
  • Cleveland, Ohio
    Cleveland Clinic Taussig Institute, Case Comprehensive Cancer Ce
2020-07-22
Jul 22, 2020
S
First Line Chemotherapy for Classical Hodgkin Lymphoma in Russia (HL-Russia-1)
Recruiting
  • Hodgkin Lymphoma, Adult
  • Moscow, Russian Federation
    The Federal Budget-Funded Institution National Medical Surgical
2020-11-20
Nov 20, 2020
U
Nivolumab and AVD in Early-stage Unfavorable Classical Hodgkin Lymphoma
Active, not recruiting
  • Classical Hodgkin Lymphoma
  • Cologne, Germany
    University Hospital of Cologne
2021-04-06
Apr 6, 2021
N
Comparison of Melatonin or Metformin and Dacarbazine Combination Versus Dacarbazine Alone in Disseminated Melanoma - 2018
Terminated
  • Melanoma
  • St. Petersburg, Russian Federation
  • +2 more
2019-11-22
Nov 22, 2019
P
Efficacy and Safety of L19TNF in Previously Treated Patients With Advanced Stage or Metastatic Soft-tissue Sarcoma
Recruiting
  • Soft Tissue Sarcoma
  • Dacarbazine
  • onfekafusp alfa
  • Münster, Germany
    Münster University Hospital
2022-03-16
Mar 16, 2022
N
Phase II Study of Interleukin-21 (rIL-21) vs Dacarbazine (DTIC) in Patients With Metastatic or Recurrent Melanoma - 2015
Completed
Has Results
  • Melanoma
  • Los Angeles, California
  • +18 more
2020-12-08
Dec 8, 2020
U
Brentuximab Vedotin in Early Stage Hodgkin Lymphoma
Not yet recruiting
  • Hodgkin Lymphoma
  • Involved site radiotherapy
  • +6 more
  • (no location specified)
2021-09-27
Sep 27, 2021
B
Study of Nivolumab (BMS-936558) Compared With Dacarbazine in Untreated, Unresectable, or Metastatic Melanoma - 2021
Completed
Has Results
  • Melanoma
  • BMS-936558 (Nivolumab)
  • +3 more
  • Capital Federal, Buenos Aires, Argentina
  • +74 more
2021-08-02
Aug 2, 2021
U
HD21 for Advanced Stages
Recruiting
  • Classical Hodgkin Lymphoma
  • Cologne, Germany
    University Hospital of Cologne
2021-06-11
Jun 11, 2021
T
A Phase II Study of Sunitinib Versus Dacarbazine in the Treatment of Patients With Metastatic Uveal Melanoma - 2017
Completed
  • Metastatic Uveal Melanoma
  • Wirral, United Kingdom
    Clatterbridge Centre for Oncology NHS Foundation Trust
2019-10-27
Oct 27, 2019
M
PTK/ZK in Disseminated Malignant Melanoma - 2008
Terminated
  • Melanoma
  • PTK787/ZK 222584
  • Dacarbazine
  • Essen, Germany
  • +3 more
2021-09-28
Sep 28, 2021
M
Brentuximab Vedotin Plus AD in Non-bulky Limited Stage Hodgkin Lymphoma - 2019
Completed
Has Results
  • Hodgkin Lymphoma
  • Brentuximab Vedotin
  • +2 more
  • Boston, Massachusetts
  • +1 more
2020-08-10
Aug 10, 2020
T
A Pilot Trial of AVD and Brentuximab Vedotin (SGN-35) in the Treatment of Stage III-IV HIV-associated Hodgkin Lymphoma
Active, not recruiting
  • HIV Infection
  • +3 more
  • brentuximab vedotin
  • +3 more
  • Clamart, France
  • +5 more
2022-04-06
Apr 6, 2022
H
Camrelizumab Combined With AVD in the First-line Treatment for Patients With Advanced Classical Hodgkin's Lymphoma
Recruiting
  • Classical Hodgkin Lymphoma
  • Zhengzhou, Henan, China
    Henan Cancer Hospital/The affiliated Cancer Hospital of ZhengZho
2020-12-29
Dec 29, 2020
A
Masitinib in Non-Resectable or Metastatic Stage 3/4 Melanoma Carrying a Mutation in the Juxta Membrane Domain of c-Kit - 2019
Terminated
  • Metastatic Melanoma
  • Charlotte, North Carolina
  • +8 more
2020-11-03
Nov 3, 2020
N
Phase II Study of Filgrastim (G-CSF) Plus ABVD in the Treatment of HIV-Associated Hodgkin's Disease - 1999
Completed
  • HIV Infections
  • Hodgkin's Disease
  • Vinblastine sulfate
  • +4 more
  • Birmingham, Alabama
  • +7 more
2021-10-26
Oct 26, 2021
M
Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Participants With Advanced Melanoma (MK-3475-002/P08719/KEYNOTE-002) - 2019
Completed
Has Results
  • Malignant Melanoma
  • Pembrolizumab
  • +4 more
  • (no location specified)
2020-04-29
Apr 29, 2020