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Decitabine

Decitabine is a drug used to treat Acute Myeloid Leukemia, Myelodysplastic Syndrome, Myelodysplastic Syndromes, and other conditions. Decitabine is being actively studied in 79 studies and prior, has been studied in 93.

Top SponsorsTop SitesTop Investigators
M.D. Anderson Cancer CenterUniversity of Texas MD Anderson Cancer CenterHan weidong
National Cancer Institute (NCI)M D Anderson Cancer CenterQifa Liu
Eisai Inc.Roswell Park Cancer InstituteMing Hou
STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS
LAST UPDATED
C
Pevonedistat and Decitabine in Treating Patients With High Risk Acute Myeloid Leukemia
Active, not recruiting
  • Acute Myeloid Leukemia
  • +5 more
  • Decitabine
  • +3 more
  • Duarte, California
    City of Hope Medical Center
2022-02-17
Feb 17, 2022
N
Testing Nivolumab in Combination With Decitabine and Venetoclax in Patients With Newly Diagnosed TP53 Gene Mutated Acute Myeloid Leukemia
Suspended
  • Acute Myeloid Leukemia
  • Decitabine
  • +2 more
  • Columbus, Ohio
    Ohio State University Comprehensive Cancer Center
2022-04-05
Apr 5, 2022
S
Decitabine Plus Carboplatin in the Treatment of Metastatic TNBC - 2021
Terminated
  • Breast Neoplasm
  • Shanghai, Shanghai, China
    Ruijin Hospital, Shanghai Jiaotong University School of Medicine
2022-03-28
Mar 28, 2022
M
Tagraxofusp and Decitabine for the Treatment of Chronic Myelomonocytic Leukemia
Recruiting
  • Chronic Myelomonocytic Leukemia
  • +3 more
  • Decitabine
  • Tagraxofusp-erzs
  • Houston, Texas
    M D Anderson Cancer Center
2022-03-04
Mar 4, 2022
N
Bortezomib, Sorafenib Tosylate, and Decitabine in Treating Patients With Acute Myeloid Leukemia
Active, not recruiting
  • Acute Myeloid Leukemia
  • +3 more
  • Columbus, Ohio
    Ohio State University Comprehensive Cancer Center
2022-03-31
Mar 31, 2022
C
Navitoclax, Venetoclax, and Decitabine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Previously Treated With Venetoclax
Not yet recruiting
  • Recurrent Acute Myeloid Leukemia
  • Refractory Acute Myeloid Leukemia
  • Decitabine
  • +2 more
  • Duarte, California
    City of Hope Comprehensive Cancer Center
2022-02-08
Feb 8, 2022
U
Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients
Active, not recruiting
  • Acute Myelogenous Leukemia
  • Decitabine
  • Rochester, New York
    University of Rochester
2021-12-08
Dec 8, 2021
T
A Study of Pevonedistat Combined With Decitabine and Cedazuridine in Adults With Higher-risk Myelodysplastic Syndromes
Withdrawn
  • Myelodysplastic Syndromes (MDS)
  • (no location specified)
2021-09-23
Sep 23, 2021
M
Study of Vosaroxin and Decitabine in Older Patients With Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome - 2021
Completed
Has Results
  • Leukemia
  • Houston, Texas
    University of Texas MD Anderson Cancer Center
2022-01-13
Jan 13, 2022
S
STAT Inhibitor OPB-111077, Decitabine and Venetoclax in Treating Patients With Acute Myeloid Leukemia That Is Refractory, Relapsed or Newly Diagnosed and Ineligible for Intensive Chemotherapy
Active, not recruiting
  • Acute Myeloid Leukemia
  • +2 more
  • STAT Inhibitor OPB-111077
  • +3 more
  • Philadelphia, Pennsylvania
    Sidney Kimmel Cancer Center at Thomas Jefferson University
2022-02-04
Feb 4, 2022
V
Decitabine and Gemcitabine for Pancreatic Cancer and Sarcoma
Active, not recruiting
  • Pancreatic Ductal Adenocarcinoma
  • Sarcoma
  • Iowa City, Iowa
    University of Iowa Hospitals and Clinics
2021-12-03
Dec 3, 2021
J
Decitabine for Coronavirus (COVID-19) Pneumonia- Acute Respiratory Distress Syndrome (ARDS) Treatment: DART Trial
Recruiting
  • COVID-19
  • Decitabine
  • Placebo Saline
  • Baltimore, Maryland
    Johns Hopkins University
2022-02-07
Feb 7, 2022
C
Pembrolizumab in Combination With Decitabine and Hypofractionated Index Lesion Radiation in Pediatrics and Young Adults
Recruiting
  • Childhood Solid Tumor
  • +5 more
  • Cincinnati, Ohio
    Cincinnati Children's Hospital Medical Center
2022-02-13
Feb 13, 2022
C
Pembrolizumab and Decitabine With or Without Venetoclax in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome That Is Newly-Diagnosed, Recurrent, or Refractory
Recruiting
  • Acute Myeloid Leukemia
  • +5 more
  • Decitabine
  • +2 more
  • Duarte, California
    City of Hope Comprehensive Cancer Center
2022-03-09
Mar 9, 2022
U
Decitabine With Ruxolitinib or Fedratinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms
Recruiting
  • Acute Myeloid Leukemia
  • +8 more
  • Decitabine
  • +3 more
  • Seattle, Washington
    Fred Hutch/University of Washington Cancer Consortium
2022-02-25
Feb 25, 2022
U
Decitabine and Talazoparib in Untreated AML and R/R AML
Active, not recruiting
  • Acute Myeloid Leukemia
  • Baltimore, Maryland
    University of Maryland Greenebaum Comprehensive Cancer Center
2021-10-05
Oct 5, 2021
W
Single Agent Decitabine in TP53 Mutated Relapsed/Refractory Acute Myeloid Leukemia
Active, not recruiting
Has Results
  • Acute Myeloid Leukemia
  • Acute Myeloid Leukemia, Relapsed, Adult
  • Decitabine
  • +4 more
  • Saint Louis, Missouri
    Washington University School of Medicine
2022-02-18
Feb 18, 2022
U
Study of Pembrolizumab Combined With Decitabine and Pralatrexate in PTCL and CTCL
Recruiting
  • PTCL
  • CTCL
  • Charlottesville, Virginia
    University of Virginia
2022-02-10
Feb 10, 2022
I
Efficacy and Safety of Low-dose Decitabine in Refractory Aplastic Anemia
Recruiting
  • Refractory Aplastic Anemia
  • Decitabine
  • Tianjin, Tianjin, China
    Regenerative Medicine Center
2021-05-10
May 10, 2021
S
Dose-Escalation Study of E7727, an Oral Cytidine Deaminase Inhibitor With Oral Decitabine in Subjects With Solid Tumors
Recruiting
  • Solid Tumor
  • Los Angeles, California
  • +1 more
2021-11-18
Nov 18, 2021
B
5-Azacitidine and Decitabine Epigenetic Therapy for Myeloid Malignancies
Recruiting
  • Myelodysplastic Syndromes
  • MDS/MPN Crossover Syndromes
  • Cleveland, Ohio
    Cleveland Medical Center, University Hospitals Seidman Cancer Ce
2021-08-19
Aug 19, 2021
M
Decitabine and Tretinoin in Treating Patients With Myelodysplastic Syndromes
Active, not recruiting
  • Myelodysplastic Syndromes
  • decitabine
  • +6 more
  • New York, New York
    Memorial Sloan Kettering Cancer Center
2021-05-07
May 7, 2021
R
Genetically Modified T Cells and Decitabine in Treating Patients With Recurrent or Refractory Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Active, not recruiting
  • Recurrent Fallopian Tube Carcinoma
  • +2 more
  • Aldesleukin
  • +4 more
  • Buffalo, New York
    Roswell Park Cancer Institute
2022-03-03
Mar 3, 2022
Y
GLAD-AML - Glasdegib (Pf-04449913) With Two Standard Decitabine Regimens for Older Patients With Poor-risk Acute Myeloid Leukemia - 2020
Terminated
Has Results
  • ACUTE MYELOID LEUKEMIA
  • New Haven, Connecticut
    Yale Cancer Center/Smilow
2021-09-18
Sep 18, 2021
S
Low-dose Decitabine for the Treatment of Decreased Donor Chimerism After Allogeneic Stem Cell Transplantation - 2021
Completed
  • Response Rate
  • Decitabine
  • Shanghai, Shanghai, China
    Blood & Marrow Transplantation Center, RuiJin Hospital
2021-05-19
May 19, 2021