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cc-486

Cc 486 is a drug used to treat Carcinoma, Non-Small-Cell Lung, Myelodysplastic Syndromes, Acute Myeloid Leukemia, and other conditions. Cc 486 is being actively studied in 11 studies and prior, has been studied in 5.

Top SponsorsTop SitesTop Investigators
CelgeneIstituto Nazionale Dei TumoriValeria Santini
AbbVieMD Anderson Cancer Center
Gilead SciencesCentre Rene Gauducheau Centre de Lutte Contre Le Cancer Nantes Atlantique
STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS
LAST UPDATED
H
Duvelisib in Combination With CC-486 in Lymphoid Malignancy
Recruiting
  • Non Hodgkin Lymphoma
  • +3 more
  • Tampa, Florida
    Moffitt Cancer Center
2021-09-23
Sep 23, 2021
C
Expanded Access for CC-486
Approved for marketing
  • Acute Myelogenous Leukemia (AML)
  • CC-486
  • Summit, New Jersey
    Celgene
2020-09-16
Sep 16, 2020
T
Study of Pembrolizumab With or Without CC-486 in Patients With Platinum-resistant Ovarian Cancer - 2021
Completed
  • Epithelial Ovarian Cancer
  • CC-486
  • Pembrolizumab
  • Los Angeles, California
  • +3 more
2021-09-22
Sep 22, 2021
M
A Study of Lenalidomide and CC-486 With Radiation Therapy in Patients With Plasmacytoma
Recruiting
  • Plasmacytoma
  • +2 more
  • CC-486
  • +2 more
  • Basking Ridge, New Jersey
  • +6 more
2021-12-01
Dec 1, 2021
C
A Study to Assess Safety and Tolerability of CC-486 (ONUREG®, Oral Azacitidine) in Combination Therapy in Participants With Acute Myeloid Leukemia (AML)
Recruiting
  • Leukemia, Myeloid, Acute
  • Stanford, California
  • +8 more
2021-11-15
Nov 15, 2021
C
A Study to Evaluate Long-term Safety in Subjects With Solid Tumors and Hematological Disorders.
Active, not recruiting
  • Hematologic Neoplasm
  • Neoplasms
  • CC-486
  • Gainesville, Florida
  • +2 more
2021-01-15
Jan 15, 2021
U
A Dose-Finding and Efficacy Study of Venetoclax, CC-486, and Obinutuzumab in Follicular Lymphoma
Recruiting
  • Follicular Lymphoma
  • Chicago, Illinois
    University of Chicago Medical Center
2021-11-12
Nov 12, 2021
C
Safety and Efficacy Study of CC-486 With MK-3475 to Treat Locally Advanced or Metastatic Non-small Cell Lung Cancer
Active, not recruiting
Has Results
  • Carcinoma, Non-Small-Cell Lung
  • CC-486
  • +2 more
  • Glendale, Arizona
  • +32 more
2021-06-09
Jun 9, 2021
G
Study of Magrolimab Combinations in Participants With Myeloid Malignancies
Recruiting
  • Myeloid Malignancies
  • Magrolimab
  • +6 more
  • Duarte, California
  • +5 more
2021-11-18
Nov 18, 2021
U
Pilot Study of CC 486 (Oral Azacitidine) Plus BSC as Maintenance After sc Azacitidine in Elderly HR-IPSS-R MDS Patients
Recruiting
  • MDS
  • CMML
  • CC-486
  • Florence, Italy
    AOU Careggi- University of Florence
2021-03-16
Mar 16, 2021
K
Evaluating in Vivo AZA Incorporation in Mononuclear Cells Following Vidaza or CC486
Active, not recruiting
  • Myelodysplastic Syndromes
  • +2 more
  • Newcastle, New South Wales, Australia
  • +10 more
2021-08-30
Aug 30, 2021
C
A Phase 1 Study of CC-486 as a Single Agent and in Combination With Carboplatin or ABI-007 in Subjects With Relapsed or Refractory Solid Tumors - 2015
Completed
  • Urinary Bladder Neoplasms
  • +7 more
  • CC-486
  • +2 more
  • Scottsdale, Arizona
  • +12 more
2019-11-07
Nov 7, 2019
C
Safety and Efficacy Study of Nab®-Paclitaxel With CC-486 or Nab®-Paclitaxel With Durvalumab, and Nab®-Paclitaxel Monotherapy as Second/Third-line Treatment for Advanced Non-small Cell Lung Cancer
Active, not recruiting
Has Results
  • Carcinoma, Non-Small-Cell Lung
  • nab-paclitaxel IV
  • +2 more
  • San Francisco, California
  • +33 more
2021-04-13
Apr 13, 2021
C
Bioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic Malignancies - 2018
Completed
  • Hematological Neoplasms
  • +19 more
  • Scottsdale, Arizona
  • +9 more
2020-05-11
May 11, 2020
C
Safety and Efficacy of CC-486 in Previously Treated Patients With Locally Advanced or Metastatic Nasopharyngeal Carcinoma - 2017
Completed
Has Results
  • Nasopharyngeal Neoplasms
  • CC-486
  • Atlanta, Georgia
  • +24 more
2018-11-20
Nov 20, 2018
C
Study to Assess the Efficacy and Safety of the Epigenetic Modifying Effects of CC-486 (Oral Azacitidine) in Combination With Fulvestrant - 2017
Terminated
Has Results
  • Breast Neoplasms
  • Chandler, Arizona
  • +34 more
2018-12-12
Dec 12, 2018
A
A Study of Oral Venetoclax Tablets and Oral Azacitidine Versus Oral Azacitidine as Maintenance Therapy in Adult Participants With Acute Myeloid Leukemia in First Remission After Conventional Chemotherapy
Recruiting
  • Acute Myeloid Leukemia (AML)
  • Birmingham, Alabama
  • +226 more
2021-11-30
Nov 30, 2021
C
Safety Study of Oral Azacitidine (CC-486) as Maintenance Therapy After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Participants With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS). - 2017
Completed
Has Results
  • Leukemia, Myeloid, Acute
  • Myelodysplastic Syndromes
  • CC-486
  • New York, New York
  • +4 more
2018-10-22
Oct 22, 2018