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everolimus

Everolimus is a drug used to treat Breast Cancer, Neuroendocrine Tumors, Renal Cell Carcinoma, and other conditions. Everolimus is being actively studied in 84 studies and prior, has been studied in 240.

Top SponsorsTop SitesTop Investigators
Novartis PharmaceuticalsNovartis Investigative SiteHelio Tedesco Silva Junior
M.D. Anderson Cancer CenterMemorial Sloan Kettering Cancer CenterIngrid Mayer, MD
National Cancer Institute (NCI)Dana-Farber Cancer InstituteTaofeek K. Owonikoko
STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS
LAST UPDATED
G
A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With Exemestane Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer)
Not yet recruiting
  • Estrogen Receptor (ER)-Positive, HER2-negative, Locally Advanced or Metastatic Breast Cancer
  • (no location specified)
2022-03-23
Mar 23, 2022
M
Everolimus (RAD001) in Metastatic Transitional Cell Carcinoma of the Urothelium - 2021
Completed
  • Bladder Cancer
  • Metastatic Transitional Cell Carcinoma
  • Everolimus
  • New York, New York
    Memorial Sloan Kettering Cancer Center
2021-12-16
Dec 16, 2021
N
Phase I-II Everolimus and Sorafenib in Recurrent High-Grade Gliomas - 2021
Completed
Has Results
  • Brain Tumor
  • +2 more
  • Bethesda, Maryland
    National Institutes of Health Clinical Center, 9000 Rockville Pi
2022-01-07
Jan 7, 2022
Y
Neoadj ph 2 AI Plus Everolimus in Postmenopausal Women w/ ER Pos/HER2 Neg, Low Risk Score - 2021
Terminated
Has Results
  • Breast Cancer
  • Everolimus
  • New Haven, Connecticut
    Yale University
2022-01-12
Jan 12, 2022
Y
Lenvatinib and Everolimus in Renal Cell Carcinoma (RCC)
Recruiting
  • Renal Cell Carcinoma
  • Iowa City, Iowa
    University of Iowa Hospitals and Clinics
2021-12-13
Dec 13, 2021
U
Everolimus With and Without Temozolomide in Adult Low Grade Glioma - 2021
Terminated
  • Low Grade Glioma
  • +3 more
  • San Francisco, California
    University of California, San Francisco
2021-11-03
Nov 3, 2021
F
Anlotinib Plus Everolimus as First-line Treatment for Advanced Non Clear Cell Renal Cell Carcinoma
Not yet recruiting
  • Renal Cell Carcinoma
  • Anlotinib hydrochloride
  • everolimus
  • Shanghai, China
    270 Dongan Road, Fudan University Shanghai Cancer Center
2021-11-05
Nov 5, 2021
T
Study of Everolimus and Sorafenib in Patients With Advanced Thyroid Cancer Who Progressed on Sorafenib Alone
Active, not recruiting
  • Differentiated Thyroid Cancer
  • Philadelphia, Pennsylvania
    Hospital of the University of Pennsylvania
2021-10-18
Oct 18, 2021
U
Itacitinib + Everolimus in Hodgkin Lymphoma
Recruiting
  • Classical Hodgkin Lymphoma
  • Philadelphia, Pennsylvania
    Abramson Cancer Center of the University of Pennsylvania
2021-07-23
Jul 23, 2021
E
Study of Everolimus (RAD001) in Combination With Lenalidomide - 2020
Completed
Has Results
  • Solid Organ Malignancies
  • +2 more
  • Atlanta, Georgia
  • +1 more
2021-11-19
Nov 19, 2021
S
A Trial of Neoadjuvant Everolimus Plus Letrozole Versus FEC in Women With ER-positive, HER2-negative Breast Cancer - 2020
Completed
  • Breast Cancer
  • Everolimus
  • +4 more
  • Guangzhou, Guangdong, China
    Sun-Yat-Sen Memorial Hospital of Sun-Yat-Sen University
2021-09-22
Sep 22, 2021
N
A Pilot Study To Evaluate The Effects of Everolimus on Brain mTOR Activity and Cortical Hyperexcitability in TSC and FCD - 2017
Completed
Has Results
  • Epilepsy
  • +2 more
  • Everolimus
  • New York, New York
    New York University Langone Medical Center
2021-08-31
Aug 31, 2021
A
Evaluation of the Safety and Tolerability of Niraparib With Everolimus in Advanced Gynecologic Malignancies and Breast
Active, not recruiting
  • Breast Cancer
  • Ovarian Cancer
  • Sioux Falls, South Dakota
    Avera Cancer Institute
2021-08-24
Aug 24, 2021
U
Study of Dasatinib in Combination With Everolimus for Children and Young Adults With Gliomas Harboring Platelet-Derived Growth Factor Receptor (PDGFR) Alterations - 2019
Terminated
  • Glioma
  • +2 more
  • Ann Arbor, Michigan
    University of Michigan Cancer Center
2021-10-12
Oct 12, 2021
U
Letrozole and Lapatinib Followed by Everolimus in Women With Advanced Breast Cancer - 2016
Terminated
Has Results
  • Breast Neoplasms
  • +2 more
  • Baltimore, Maryland
    University of Maryland Marlene & Stewart Greenebaum Cancer Cente
2022-02-09
Feb 9, 2022
H
Comparison of the Efficacy and Safety of Sirolimus Versus Everolimus Versus Mycophenolate in Kidney Transplantation - 2021
Completed
  • Kidney Transplant Infection
  • São Paulo, Sao Paulo, Brazil
    Hospital do Rim
2021-08-23
Aug 23, 2021
S
A Phase 0 /II Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for Resection
Active, not recruiting
  • Glioblastoma Multiforme
  • Glioma of Brain
  • Chandler, Arizona
  • +2 more
2022-03-10
Mar 10, 2022
T
UPCC 36315 A Phase II Study Of Everolimus (RAD001) And Lenvatinib (E7080) In Patients With Metastatic Differentiated Thyroid Cancer Who Have Progressed on Lenvatinib Alone
Suspended
  • Thyroid Cancer
  • Philadelphia, Pennsylvania
    Abramson Cancer Center of the University of Pennsylvania
2021-10-07
Oct 7, 2021
M
ARN 509 Plus Everolimus in Men With Progressive Metastatic Castration-Resistant Prostate Cancer After Treatment With Abiraterone Acetate - 2021
Completed
  • Prostate Cancer
  • New York, New York
    Memorial Sloan Kettering Cancer Center
2021-06-29
Jun 29, 2021
U
Everolimus for Children With Recurrent or Progressive Ependymoma
Active, not recruiting
  • Recurrent Childhood Ependymoma
  • Everolimus
  • Stanford, California
  • +3 more
2022-01-31
Jan 31, 2022
M
Pazopanib and Everolimus in PI3KCA Mutation Positive/PTEN Loss Patients
Active, not recruiting
  • Advanced Cancers
  • Solid Tumors
  • Houston, Texas
    University of Texas MD Anderson Cancer Center
2021-06-15
Jun 15, 2021
H
Topical Everolimus in Patients With Tuberous Sclerosis Complex
Withdrawn
  • Facial Angiofibromas
  • Everolimus
  • Placebo
  • Bron, France
    Hopital Femme Mère Enfant
2021-04-28
Apr 28, 2021
N
A Study of Safety and Efficacy of Everolimus in Taiwanese Patients With Tuberous Sclerosis Complex Who Have Renal Angiomyolipoma (TSC-AML)
Not yet recruiting
  • Renal Angiomyolipoma
  • Everolimus
  • (no location specified)
2022-02-16
Feb 16, 2022
M
Lenvatinib and Everolimus in Treating Patients With Advanced, Unresectable Carcinoid Tumors
Recruiting
  • Advanced Carcinoid Tumor
  • +4 more
  • Houston, Texas
    M D Anderson Cancer Center
2021-10-19
Oct 19, 2021
W
VEGFR/PDGFR Dual Kinase Inhibitor X-82 and Everolimus for Treating Patients With Pancreatic Neuroendocrine Tumors - 2020
Terminated
Has Results
  • Adenocarcinoma
  • Pancreatic Neoplasms
  • Saint Louis, Missouri
  • +1 more
2021-06-15
Jun 15, 2021