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pemetrexed

Pemetrexed is a drug used to treat Non Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Mesothelioma, and other conditions. Pemetrexed is being actively studied in 190 studies and prior, has been studied in 213.

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Eli Lilly and CompanyFor additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.Si-Yu Wang
Merck Sharp & Dohme Corp.Research SiteZhenyu Pan
Hoffmann-La RocheAsan Medical CenterChang Jian Hua
STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS
LAST UPDATED
S
Pemetrexed for the Treatment of Chordoma
Active, not recruiting
  • Chordoma
  • Pemetrexed
  • Santa Monica, California
    John Wayne Cancer Institute
2022-03-08
Mar 8, 2022
H
Orelabrutinib Combined With Pemetrexed For Relapsed/Refractory Central Nervous System Lymphoma
Recruiting
  • Central Nervous System Lymphoma
  • Zhengzhou, Henan, China
    Henan Cancer Hospital/The affiliated Cancer Hospital of ZhengZho
2022-01-28
Jan 28, 2022
B
Study of Cytoreductive Surgery and Hyperthermic Intraoperative Chemotherapy With Pemetrexed and Cisplatin for MPM - 2019
Terminated
  • Mesothelioma
  • Houston, Texas
    Baylor St Lukes
2022-03-15
Mar 15, 2022
M
Pazopanib or Pemetrexed and Crizotinib in Advanced Cancer - 2021
Terminated
  • Advanced Cancers
  • Crizotinib (Xalkori)
  • +2 more
  • Houston, Texas
    University of Texas MD Anderson Cancer Center
2021-09-03
Sep 3, 2021
T
Intrathecal Pemetrexed for Leptomeningeal Metastasis
Recruiting
  • Leptomeningeal Metastases
  • Pemetrexed
  • +3 more
  • Changchun, Jilin, China
    The First Hospital of Jilin University
2022-03-17
Mar 17, 2022
U
Staggered, Chemo-Immunotherapy With Durvalumab, MEDI4736 Pemetrexed & Carboplatin (PC) for Metastatic Non-Squamous NSCLC
Recruiting
  • Non-Small Cell Lung Cancer Metastatic
  • Salt Lake City, Utah
    Huntsman Cancer Institute at University of Utah
2022-03-01
Mar 1, 2022
S
Pemetrexed and Gemcitabine in Patients With Advanced Non-Small Cell Lung Cancer - 2009
Completed
Has Results
  • Lung Cancer
  • Nashville, Tennessee
    Tennessee Oncology
2022-02-21
Feb 21, 2022
A
Cabozantinib With Pemetrexed in Advanced Non-small Cell Lung Cancer, Urothelial Cancer and Malignant Mesothelioma
Recruiting
  • Non Small Cell Lung Cancer
  • +3 more
  • Augusta, Georgia
    Augusta University Georgia Cancer Center
2022-03-06
Mar 6, 2022
S
A Study of BBI608 in Combination With Pemetrexed and Cisplatin in Adult Patients With Malignant Pleural Mesothelioma - 2018
Completed
Has Results
  • Malignant Pleural Mesothelioma
  • Non-Small Cell Lung Cancer
  • Chiba, Japan
  • +1 more
2021-09-05
Sep 5, 2021
M
A Phase II Study of Neoadjuvant Sotorasib in Combination With Cisplatin or Carboplatin and Pemetrexed for Surgically Resectable Stage IIA-IIIB Non-Squamous Non-Small Cell Lung Cancer With a KRAS p.G12C Mutation
Recruiting
  • Lung Cancer
  • AMG 510
  • +3 more
  • Houston, Texas
    M D Anderson Cancer Center
2022-03-30
Mar 30, 2022
N
Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid Tumors
Recruiting
  • Carcinoma, Non-Small-Cell Lung
  • +7 more
  • Augusta, Georgia
    Augusta University Georgia Cancer Center
2021-07-31
Jul 31, 2021
R
Dose Individualization of Pemetrexed - IMPROVE-II
Recruiting
  • Non Small Cell Lung Cancer
  • Mesothelioma
  • Pemetrexed
  • 's-Hertogenbosch, Netherlands
  • +4 more
2021-09-14
Sep 14, 2021
R
Dose Individualization of Pemetrexed - IMPROVE-I
Recruiting
  • Non Small Cell Lung Cancer
  • Mesothelioma
  • Pemetrexed
  • 's-Hertogenbosch, Netherlands
  • +4 more
2021-09-14
Sep 14, 2021
R
Dose Individualization of Pemetrexed - IMPROVE-III
Recruiting
  • Non Small Cell Lung Cancer
  • Mesothelioma
  • Pemetrexed
  • 's-Hertogenbosch, Netherlands
  • +4 more
2021-09-14
Sep 14, 2021
M
Pemetrexed and Avelumab in Treating Patients With MTAP-Deficient Metastatic Urothelial Cancer
Recruiting
  • Infiltrating Bladder Urothelial Carcinoma Sarcomatoid Variant
  • +6 more
  • Houston, Texas
    M D Anderson Cancer Center
2021-11-17
Nov 17, 2021
C
Pemetrexed in Maintenance in Patients With Impaired Renal Function, 2 Dose Calculation Strategies - 2020
Completed
  • Non-small Cell Lung Cancer
  • Pemetrexed
  • Chalon-sur-Saône, France
  • +2 more
2021-05-21
May 21, 2021
M
A Study of Pembrolizumab in Combination With Cisplatin and Pemetrexed in Advanced Malignant Pleural Mesothelioma (MPM) (MK-3475-A17)
Active, not recruiting
  • Mesothelioma
  • Nishinomiya, Hyogo, Japan
  • +3 more
2022-03-11
Mar 11, 2022
N
Pemetrexed Disodium in the Cerebrospinal Fluid of Patients With Leptomeningeal Metastases - 2011
Completed
  • Brain and Central Nervous System Tumors
  • +10 more
  • Pemetrexed
  • Chicago, Illinois
    Robert H. Lurie Comprehensive Cancer Center at Northwestern Univ
2021-09-03
Sep 3, 2021
T
Study of Chemotherapy and PD-1 Inhibitor Combination With Anti-angiogenesis to Treat Elderly Lung Cancer
Not yet recruiting
  • Non-Small Cell Lung Cancer
  • Tianjin, Tianjin, China
    Tianjin Medical University Cancer Institute and Hospital
2022-03-01
Mar 1, 2022
X
A Study of Sintilimab Compared With Docetaxel or Pemetrexed as Second-line Treatment for Patients With Stage IV Nonsquamous Non-small Cell Lung Cancer After Failure With Platinum-Containing Chemotherapy
Recruiting
  • Nonsquamous Non-Small Cell Lung Cancer
  • Yichang, Hubei, China
    Department of Medical Oncology, Central Hospital of Yichang City
2021-11-05
Nov 5, 2021
T
A Study of Sargramostim Plus Pembrolizumab With or Without Pemetrexed in Patients With Advance Non-small Cell Lung Cancer After Completion of Chemoimmunotherapy
Recruiting
  • Advanced Lung Non-Small Cell Carcinoma
  • Non-Small Cell Carcinoma of Lung, TNM Stage 4
  • Granulocyte-Macrophage Colony-Stimulating Factor
  • +4 more
  • Boston, Massachusetts
    Tufts Medical Center
2022-01-05
Jan 5, 2022
N
Pembrolizumab Plus Pemetrexed for Elderly Patients With Non-Sq NSCLC With PD-L1 < 50%: CJLSG1901
Recruiting
  • Non-squamous Non-small-cell Lung Cancer
  • Cancer, Lung
  • Nagoya, Aichi, Japan
    National Hospital Organization Nagoya Medical Center
2021-04-23
Apr 23, 2021
N
Carboplatin Plus Pemetrexed Plus Atezolizumab Plus Bevacizumab in Chemotherapy and Immunotherapy-naïve Patients With Stage IV Non-squamous Non-small Cell Lung Cancer
Active, not recruiting
  • NSCLC Stage IV
  • NSCLC, Recurrent
  • Chicago, Illinois
  • +6 more
2022-02-16
Feb 16, 2022
S
Study of Atezolizumab Combination Carboplatin + Paclitaxel + Bevacizumab in EGRF Mutation or ALK Translocation NSCLC
Recruiting
  • Non-small Cell Lung Cancer
  • Seoul, Gangnamgu, Korea, Republic of
    Samsung Medical Center
2021-12-27
Dec 27, 2021
J
Lenvatinib in Combination With Carboplatin Pemetrexed and Pembrolizumab for NSCLC With EGFR Mutations
Not yet recruiting
  • Non-squamous Non-small-cell Lung Cancer
  • EGFR Activating Mutation
  • Urayasu, Chiba, Japan
  • +9 more
2022-02-17
Feb 17, 2022