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trc105

Trc105 is a drug used to treat Glioblastoma Multiforme, Prostate Cancer, Advanced Angiosarcoma, and other conditions. Trc105 is being actively studied in 1 study and prior, has been studied in 9.

Top SponsorsTop SitesTop Investigators
Tracon Pharmaceuticals Inc.National Institutes of Health Clinical Center, 9000 Rockville PikeAndrea Apolo, M.D.
National Cancer Institute (NCI)Ohio State UniversityEdwin Posadas, MD
University of Alabama at BirminghamCleveland ClinicErica Stringer-Reasor
STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS
LAST UPDATED
U
Preoperative Combination of Letrozole, Everolimus, and TRC105 in Postmenopausal Hormone-Receptor Positive and Her2 Negative Breast Cancer
Active, not recruiting
  • Breast Cancer
  • Birmingham, Alabama
    University of Alabama at Birmingham
2022-01-24
Jan 24, 2022
T
Open Label Continuation Study of TRC105 for Patients Who Have Completed a Prior TRC105 Trial
No longer available
  • Solid Tumors
  • TRC105
  • +4 more
  • Santa Monica, California
    UCLA
2021-01-28
Jan 28, 2021
U
A Study of TRC105 in Combination With Paclitaxel/Carboplatin and Bevacizumab in Non-Squamous Cell Lung Cancer - 2019
Completed
  • Lung Cancer
  • TRC105
  • Birmingham, Alabama
    UAB Comprehensive Cancer Center
2021-06-24
Jun 24, 2021
C
Study of TRC105 With Abiraterone and With Enzalutamide in Prostate Cancer Patients Progressing on Therapy - 2019
Completed
Has Results
  • Prostate Cancer
  • TRC105
  • +2 more
  • Los Angeles, California
    Cedars Sinai Medical Center
2020-12-04
Dec 4, 2020
T
Study of TRC105 + Paclitaxel/Carboplatin and Bevacizumab in Patients With NSCLC - 2019
Completed
Has Results
  • Non Small Cell Lung Cancer
  • TRC105
  • (no location specified)
2019-10-04
Oct 4, 2019
T
Study of TRC105 and Bevacizumab in Patients With Refractory Gestational Trophoblastic Neoplasia (GTN) - 2018
Terminated
Has Results
  • Gestational Trophoblastic Neoplasia
  • +3 more
  • Boston, Massachusetts
  • +2 more
2019-07-09
Jul 9, 2019
T
Trial of TRC105 and Pazopanib Versus Pazopanib Alone in Patients With Advanced Angiosarcoma - 2019
Completed
Has Results
  • Advanced Angiosarcoma
  • Tucson, Arizona
  • +38 more
2020-05-11
May 11, 2020
T
A Phase 2 Evaluation of TRC105 In Combination With Bevacizumab in Patients With Glioblastoma - 2015
Completed
Has Results
  • Glioblastoma
  • Glioblastoma Multiforme
  • Cincinnati, Ohio
  • +3 more
2019-05-21
May 21, 2019
T
Open Label Dose-Finding Study of TRC105 Plus Capecitabine for Metastatic Breast Cancer - 2014
Completed
Has Results
  • Metastatic Breast Cancer
  • Birmingham, Alabama
  • +1 more
2019-02-28
Feb 28, 2019
N
A Phase I/II Study of TRC105 in Metastatic Castrate Resistant Prostate Cancer (CRPC) - 2015
Completed
Has Results
  • Prostate Cancer
  • Metastatic Castrate Resistant Prostate Cancer
  • TRC105
  • Bethesda, Maryland
    National Institutes of Health Clinical Center, 9000 Rockville Pi
2018-04-13
Apr 13, 2018
N
TRC105 for Liver Cancer That Has Not Responded to Sorafenib - 2015
Completed
Has Results
  • Hepatocellular Carcinoma
  • +2 more
  • TRC105
  • Bethesda, Maryland
    National Institutes of Health Clinical Center, 9000 Rockville Pi
2017-06-29
Jun 29, 2017
N
TRC105 in Adults With Advanced/Metastatic Urothelial Carcinoma - 2014
Completed
Has Results
  • Urothelial Carcinoma
  • +4 more
  • TRC105
  • Bethesda, Maryland
    National Institutes of Health Clinical Center, 9000 Rockville Pi
2016-11-16
Nov 16, 2016
N
TRC105 for Recurrent Glioblastoma - 2014
Terminated
Has Results
  • Glioblastoma Multiforme
  • TRC105
  • Bethesda, Maryland
    National Institutes of Health Clinical Center, 9000 Rockville Pi
2015-10-06
Oct 6, 2015