Locally Advanced Malignant Solid Neoplasm Clinical Trials

STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS
LAST UPDATED
N
Testing the Combination of New Anti-cancer Drug Peposertib With Avelumab and Radiation Therapy for Advanced/Metastatic Solid Tumors and Hepatobiliary Malignancies
Recruiting
  • Locally Advanced Cholangiocarcinoma
  • +28 more
  • Sacramento, California
  • +6 more
2022-03-30
Mar 30, 2022
M
Pembrolizumab Before Surgery for the Treatment of Mismatch Repair Deficient Locally Advanced Solid Cancers
Recruiting
  • Locally Advanced Malignant Solid Neoplasm
  • Pembrolizumab
  • Houston, Texas
    M D Anderson Cancer Center
2022-03-22
Mar 22, 2022
N
Uprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV Cancer
Active, not recruiting
Has Results
  • Hematopoietic and Lymphoid Cell Neoplasm
  • +8 more
  • Dabrafenib Mesylate
  • +2 more
  • Los Angeles, California
  • +15 more
2022-03-25
Mar 25, 2022
N
Durvalumab in Combination With Chemotherapy in Treating Patients With Advanced Solid Tumors, (DURVA+ Study)
Recruiting
  • Locally Advanced Malignant Solid Neoplasm
  • +2 more
  • Bethesda, Maryland
    National Cancer Institute Developmental Therapeutics Clinic
2022-03-17
Mar 17, 2022
F
PLAN Intervention to Enhance Engagement of Latino Cancer Patients in Advanced Care Planning
Suspended
  • Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
  • +33 more
  • Communication Intervention
  • +2 more
  • New York, New York
  • +1 more
2022-03-02
Mar 2, 2022
M
Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for the Treatment of Advanced Solid Tumors, The PNeoVCA Study
Not yet recruiting
  • Anatomic Stage III Breast Cancer AJCC v8
  • +129 more
  • Jacksonville, Florida
    Mayo Clinic in Florida
2022-02-25
Feb 25, 2022
N
Testing AZD1775 in Advanced Solid Tumors That Have a Mutation Called SETD2
Active, not recruiting
  • Clear Cell Renal Cell Carcinoma
  • +6 more
  • Orange, California
  • +28 more
2022-03-01
Mar 1, 2022
O
SMMART Adaptive Clinical Treatment (ACT) Trial
Not yet recruiting
  • Anatomic Stage IV Breast Cancer AJCC v8
  • +18 more
  • Biopsy
  • +25 more
  • Portland, Oregon
    OHSU Knight Cancer Institute
2022-02-11
Feb 11, 2022
S
Brigatinib in Treating Patients With ALK and ROS1 Gene Alterations and Locally Advanced or Metastatic Solid Cancers
Withdrawn
  • Advanced Malignant Neoplasm
  • +10 more
  • Columbus, Ohio
    Ohio State University Comprehensive Cancer Center
2022-02-15
Feb 15, 2022
M
Pevonedistat and Pembrolizumab for the Treatment of dMMR/MSI-H Metastatic or Locally Advanced Unresectable Solid Tumor
Active, not recruiting
  • Locally Advanced Malignant Solid Neoplasm
  • +2 more
  • Houston, Texas
    M D Anderson Cancer Center
2022-01-18
Jan 18, 2022
M
Larotrectinib for the Treatment of NTRK Amplification Positive, Locally Advanced or Metastatic Solid Tumors
Recruiting
  • Locally Advanced Malignant Solid Neoplasm
  • Metastatic Malignant Solid Neoplasm
  • Larotrectinib Sulfate
  • Houston, Texas
    M D Anderson Cancer Center
2021-12-21
Dec 21, 2021
M
Assessment of Verbal Comprehension and Cognitive Processes in Patients Admitted to the Palliative and Supportive Care Unit
Recruiting
  • Hematopoietic and Lymphoid Cell Neoplasm
  • +3 more
  • Electroencephalography
  • Questionnaire Administration
  • Houston, Texas
    M D Anderson Cancer Center
2021-10-12
Oct 12, 2021
M
Distress Associated With Coronavirus Disease 2019 and Telehealth on Supportive Care Patients With Advanced Cancer
Recruiting
  • Advanced Malignant Solid Neoplasm
  • +6 more
  • Survey Administration
  • Houston, Texas
    M D Anderson Cancer Center
2021-10-12
Oct 12, 2021
U
CMP-001 and INCAGN01949 for Patients With Stage IV Pancreatic Cancer and Other Cancers Except Melanoma
Recruiting
  • Locally Advanced Malignant Solid Neoplasm
  • +3 more
  • Agonistic Anti-OX40 Monoclonal Antibody INCAGN01949
  • VLP-encapsulated TLR9 Agonist CMP-001
  • Scottsdale, Arizona
  • +3 more
2021-10-14
Oct 14, 2021
N
Testing the Safety of CB-5339 in Patients With Cancer - 2021
Withdrawn
  • Aggressive Non-Hodgkin Lymphoma
  • +3 more
  • p97 Inhibitor CB-5339 Tosylate
  • Bethesda, Maryland
  • +1 more
2021-08-27
Aug 27, 2021
U
Integrative Palliative Care/Psycho-Oncology Telehealth Intervention in Patients With Advanced Cancer
Recruiting
  • Advanced Malignant Solid Neoplasm
  • +2 more
  • Support Group Therapy
  • +3 more
  • San Francisco, California
    University of California, San Francisco
2021-08-20
Aug 20, 2021
M
BAY1895344 and Copanlisib for the Treatment of Molecularly Selected Patients With Advanced Solid Tumors
Not yet recruiting
  • Locally Advanced Malignant Solid Neoplasm
  • +3 more
  • Houston, Texas
    M D Anderson Cancer Center
2021-08-10
Aug 10, 2021
M
Adoption of Audio Recording in the Outpatient Supportive Care Center
Not yet recruiting
  • Advanced Malignant Solid Neoplasm
  • +4 more
  • Communication Intervention
  • Questionnaire Administration
  • Houston, Texas
    M D Anderson Cancer Center
2021-05-03
May 3, 2021
R
Phase II Trial of AZD6738 Alone and in Combination With Olaparib
Recruiting
  • Clear Cell Renal Cell Carcinoma
  • +10 more
  • San Francisco, California
    University of California, San Francisco
2021-04-05
Apr 5, 2021
M
Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors
Recruiting
  • Anatomic Stage IV Breast Cancer AJCC v8
  • +28 more
  • Houston, Texas
    M D Anderson Cancer Center
2021-02-23
Feb 23, 2021
M
Ceritinib and Everolimus in Treating Patients With Locally Advanced or Metastatic Solid Tumors or Stage IIIB-IV Non-small Cell Lung Cancer
Recruiting
  • ALK Positive
  • +5 more
  • Houston, Texas
    M D Anderson Cancer Center
2020-02-14
Feb 14, 2020