Major Depressive Disorder Clinical Trials

STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS
LAST UPDATED
U
Effects of Ghrelin Administration on Dopamine and Effort
Recruiting
  • Major Depressive Disorder
  • Tübingen, BW, Germany
    Department of Psychiatry & Psychotherapy, University of Tübingen
2022-04-07
Apr 7, 2022
N
Antidepressant Effects of TS-161 in Treatment-Resistant Depression
Recruiting
  • Major Depressive Disorder
  • +2 more
  • Placebo
  • TS-161 (50 - 100 mg)
  • Bethesda, Maryland
    National Institutes of Health Clinical Center
2022-04-07
Apr 7, 2022
N
Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression
Recruiting
  • Depression
  • +2 more
  • Arm 1 and 2 Interventions
  • +3 more
  • Bethesda, Maryland
    National Institutes of Health Clinical Center
2022-04-07
Apr 7, 2022
I
Clinical Trial of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder
Recruiting
  • Major Depressive Disorder
  • Phoenix, Arizona
  • +27 more
2022-04-07
Apr 7, 2022
N
Concurrent fMRI-guided rTMS and Cognitive Therapy for the Treatment of Major Depressive Episodes
Recruiting
  • Major Depressive Disorder
  • Sham TMS + Cognitive therapy
  • Active TMS+ Cognitive therapy
  • Bethesda, Maryland
    National Institutes of Health Clinical Center
2022-04-07
Apr 7, 2022
N
Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder
Recruiting
  • Healthy Volunteer
  • +2 more
  • Bethesda, Maryland
    National Institutes of Health Clinical Center
2022-04-07
Apr 7, 2022
M
ECT vs. Esketamine
Recruiting
  • Treatment Resistant Depression
  • Major Depressive Disorder
  • Esketamine nasal spray
  • Electroconvulsive therapy
  • Innsbruck, Tyrol, Austria
    Medical University Innsbruck
2022-04-07
Apr 7, 2022
K
Using Voice Biomarkers to Predict the Likelihood of Major Depressive Disorder - 2021
Completed
  • Major Depressive Disorder
    • San Francisco, California
    • +1 more
    2022-03-30
    Mar 30, 2022
    I
    Multicenter Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder
    Recruiting
    • Major Depressive Disorder
    • Little Rock, Arkansas
    • +16 more
    2022-04-07
    Apr 7, 2022
    C
    MAO-B Occupancy in Depressed Patients
    Recruiting
    • Major Depressive Disorder
    • Treatment Resistant Depression
    • [11C]SL25.1188 PET radiotracer
    • Toronto, Ontario, Canada
      CAMH
    2022-03-31
    Mar 31, 2022
    I
    An Open-label Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder
    Enrolling by invitation
    • Major Depressive Disorder
    • Phoenix, Arizona
    • +44 more
    2022-04-07
    Apr 7, 2022
    M
    The Efficacy of Probiotic Compared With Placebo Commitment Therapy for Treatment of Major Depressive Disorder
    Recruiting
    • Major Depressive Disorder
    • Probiotic
    • +2 more
    • Cheras, Kuala Lumpur, Malaysia
      Hospital Canselor Tuanku Muhriz UKM Medical Centre
    2022-03-30
    Mar 30, 2022
    Y
    Reducing Suicide Risk in Adolescents and Young Adults Via a Psychobehavioral Intervention to Regularize Daily Rhythms and Improve Brain Circuitry Functioning
    Not yet recruiting
    • Bipolar Disorder
    • +4 more
    • BE-SMART-DR
    • psychoeducational control comparator condition (CC)
    • New Haven, Connecticut
    • +1 more
    2022-04-05
    Apr 5, 2022
    B
    Symptom-specific TMS Targets for Depression and Anxiety
    Recruiting
    • Depression
    • +2 more
    • Transcranial magnetic stimulation
    • Boston, Massachusetts
      Brigham & Women's Hospital
    2022-03-30
    Mar 30, 2022
    M
    Comparative Effectiveness of Pharmacogenomics for Treatment of Depression - 2022
    Completed
    • Major Depressive Disorder
    • GeneSight Psychotropic test
    • Canadian Network for Mood and Anxiety Treatment (CANMAT) Best Practice Guidelines
    • Boston, Massachusetts
      Massachusetts General Hospital
    2022-04-05
    Apr 5, 2022
    P
    Pipamperone/Citalopram (PNB01) Versus Citalopram (CIT) and Versus Pipamperone (PIP) in Major Depressive Disorder (MDD) - 2012
    Completed
    Has Results
    • Major Depressive Disorder
    • PNB01 fixed dose combination of pipamperone and citalopram
    • +2 more
    • Glendale, California
    • +30 more
    2022-03-14
    Mar 14, 2022
    E
    Duloxetine Compassionate Use in Patients Who Have Completed a Previous Neuroscience Duloxetine Clinical Trial
    No longer available
    • Major Depressive Disorder
    • +3 more
    • Duloxetine Hydrochloride
    • Paddington, New South Wales, Australia
    • +12 more
    2022-04-05
    Apr 5, 2022
    M
    Sequential Bilateral Accelerated Theta Burst Stimulation in Adolescents With Suicidal Ideation
    Recruiting
    • Suicidal Ideation
    • Major Depressive Disorder
    • MagVenture TMS Therapy System w/Theta Burst Stimulation
    • Sham MagVenture TMS Therapy System w/Theta Burst Stimulation
    • Rochester, Minnesota
      Mayo Clinic in Rochester
    2022-04-04
    Apr 4, 2022
    L
    Floatation-REST (Reduced Environmental Stimulation Therapy) for Anxiety and Depression
    Active, not recruiting
    • Generalized Anxiety Disorder
    • +5 more
    • Float pool
    • Float chair
    • Tulsa, Oklahoma
      Laureate Institute for Brain Research
    2022-04-04
    Apr 4, 2022
    U
    Behavioral Activation + Cognitive Processing Therapy for PTSD and Comorbid MDD
    Active, not recruiting
    • Posttraumatic Stress Disorder
    • Major Depressive Disorder
    • Behavioral Activation
    • Cognitive Processing Therapy
    • San Diego, California
      Naval Medical Center San Diego
    2022-04-04
    Apr 4, 2022
    L
    Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa
    Active, not recruiting
    • Anorexia Nervosa
    • +4 more
    • Tulsa, Oklahoma
      Laureate Institute for Brain Research
    2022-04-04
    Apr 4, 2022
    M
    ON/OFF Stimulation and Impulsivity in Patients With Deep Brain Stimulators
    Recruiting
    • Obsessive Compulsive Disorder
    • Major Depressive Disorder
      • Boston, Massachusetts
      • +1 more
      2022-04-04
      Apr 4, 2022
      K
      Alleviating Stress by Mobile Application' for Depression
      Not yet recruiting
      • Major Depressive Disorder
      • the App
      • Seoul, Guro Gu, Korea, Republic of
        Department of Psychiatry, Korea University Guro Hospital
      2022-03-31
      Mar 31, 2022
      S
      The Effect of Psilocybin on MDD Symptom Severity and Synaptic Density
      Recruiting
      • Major Depressive Disorder
      • Depression
      • Stockholm, Sweden
        Northern Stockholm Spychiatry Clinic
      2022-04-04
      Apr 4, 2022
      U
      Stellate Ganglion Block for Major Depressive Disorder.
      Recruiting
      • Treatment Resistant Depression
      • Major Depressive Disorder
      • Bupivacaine Hydrochloride
      • Normal Saline
      • Toronto, Ontario, Canada
        St. Michael's Hospital
      2022-03-24
      Mar 24, 2022