Metastatic Malignant Solid Neoplasm Clinical Trials

STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS
LAST UPDATED
N
Atezolizumab in Treating Patients With Cancer Following Adoptive Cell Transfer
Recruiting
  • Hematopoietic and Lymphoid Cell Neoplasm
  • +2 more
  • La Jolla, California
  • +8 more
2022-04-06
Apr 6, 2022
N
Pembrolizumab and Recombinant Interleukin-12 in Treating Patients With Solid Tumors
Recruiting
  • Metastatic Malignant Solid Neoplasm
  • Unresectable Solid Neoplasm
  • Edodekin alfa
  • Pembrolizumab
  • La Jolla, California
  • +27 more
2022-04-05
Apr 5, 2022
N
Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer
Recruiting
  • Advanced Malignant Solid Neoplasm
  • +13 more
  • Nivolumab
  • Birmingham, Alabama
  • +43 more
2022-04-05
Apr 5, 2022
N
Testing the Combination of Copanlisib, Nivolumab and Ipilimumab in Patients With Advanced Cancer and Lymphoma
Active, not recruiting
  • Ann Arbor Stage III Lymphoma
  • +4 more
  • Bethesda, Maryland
  • +2 more
2022-04-05
Apr 5, 2022
N
Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid Tumors
Recruiting
  • Metastatic Malignant Solid Neoplasm
  • +3 more
  • BET Bromodomain Inhibitor ZEN-3694
  • +2 more
  • Cleveland, Ohio
  • +1 more
2022-04-05
Apr 5, 2022
N
Testing the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Immunotherapy (Nivolumab With or Without Ipilimumab) in Patients With Advanced Solid Cancers That Have Changes in the Following Genes: PIK3CA and PTEN
Recruiting
  • Advanced Malignant Solid Neoplasm
  • +3 more
  • Copanlisib Hydrochloride
  • +2 more
  • Boston, Massachusetts
  • +5 more
2022-04-05
Apr 5, 2022
N
Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
Recruiting
  • Advanced Malignant Solid Neoplasm
  • +8 more
  • Ipilimumab
  • Nivolumab
  • La Jolla, California
  • +34 more
2022-04-05
Apr 5, 2022
N
Collection and Storage of Tissue and Blood Samples From Patients With Cancer
Recruiting
  • Lymphoma
  • +6 more
  • Cytology Specimen Collection Procedure
  • Birmingham, Alabama
  • +139 more
2022-04-05
Apr 5, 2022
N
Entinostat, Nivolumab, and Ipilimumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery or Locally Advanced or Metastatic HER2-Negative Breast Cancer
Active, not recruiting
  • Breast Adenocarcinoma
  • +9 more
  • Duarte, California
  • +4 more
2022-04-05
Apr 5, 2022
N
Testing the PD-1 Antibody, MK3475, Given With Ziv-aflibercept in Patients With Advanced Cancer
Recruiting
  • Clinical Stage IV Cutaneous Melanoma AJCC v8
  • +20 more
  • Pembrolizumab
  • Ziv-Aflibercept
  • Tampa, Florida
  • +8 more
2022-04-05
Apr 5, 2022
N
Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Patients With Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial
Recruiting
  • Advanced Breast Carcinoma
  • +74 more
  • Los Angeles, California
  • +9 more
2022-04-05
Apr 5, 2022
N
Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV
Recruiting
  • Advanced Differentiated Thyroid Gland Carcinoma
  • +102 more
  • Cabozantinib S-malate
  • Nivolumab
  • Chicago, Illinois
  • +2 more
2022-04-05
Apr 5, 2022
N
PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be Removed by Surgery
Active, not recruiting
  • Advanced Breast Carcinoma
  • +25 more
  • Aurora, Colorado
  • +7 more
2022-04-02
Apr 2, 2022
N
Testing the Combination of the Anti-cancer Drugs Copanlisib, Olaparib, and MEDI4736 (Durvalumab) in Patients With Advanced Solid Tumors With Selected Mutations
Recruiting
  • Advanced Malignant Solid Neoplasm
  • +2 more
  • Copanlisib Hydrochloride
  • +2 more
  • Aurora, Colorado
  • +7 more
2022-04-01
Apr 1, 2022
N
Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations
Recruiting
  • Advanced Breast Carcinoma
  • +55 more
  • Bethesda, Maryland
  • +1 more
2022-04-01
Apr 1, 2022
N
Testing the Sequential Combination of the Anti-cancer Drugs Olaparib Followed by Adavosertib (AZD1775) in Patients With Advanced Solid Tumors With Selected Mutations and PARP Resistance, STAR Study
Suspended
  • Advanced Malignant Solid Neoplasm
  • +3 more
  • Houston, Texas
    M D Anderson Cancer Center
2022-03-31
Mar 31, 2022
S
Financial Navigation Program to Improve Understanding and Management of Financial Aspects of Cancer Care for Patients and Their Spouses
Recruiting
  • Hematopoietic and Lymphoid Cell Neoplasm
  • +2 more
  • Educational Intervention
  • +3 more
  • Fairbanks, Alaska
  • +152 more
2022-03-29
Mar 29, 2022
N
M6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
Recruiting
  • Metastatic Colorectal Carcinoma
  • +29 more
  • Los Angeles, California
  • +22 more
2022-03-29
Mar 29, 2022
N
Testing the Combination of New Anti-cancer Drug Peposertib With Avelumab and Radiation Therapy for Advanced/Metastatic Solid Tumors and Hepatobiliary Malignancies
Recruiting
  • Locally Advanced Cholangiocarcinoma
  • +28 more
  • Sacramento, California
  • +6 more
2022-03-30
Mar 30, 2022
N
Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic Cancer
Recruiting
  • Metastatic Lung Small Cell Carcinoma
  • +16 more
  • Phoenix, Arizona
  • +10 more
2022-03-25
Mar 25, 2022
N
Uprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV Cancer
Active, not recruiting
Has Results
  • Hematopoietic and Lymphoid Cell Neoplasm
  • +8 more
  • Dabrafenib Mesylate
  • +2 more
  • Los Angeles, California
  • +15 more
2022-03-25
Mar 25, 2022
M
Sapanisertib and Metformin in Treating Patients With Advanced or Metastatic Relapsed or Refractory Cancers
Active, not recruiting
  • Advanced Malignant Solid Neoplasm
  • +3 more
  • Laboratory Biomarker Analysis
  • +3 more
  • Houston, Texas
    M D Anderson Cancer Center
2022-03-24
Mar 24, 2022
A
Genetic Testing in Guiding Treatment for Patients With Brain Metastases
Recruiting
  • CDK Gene Mutation
  • +5 more
  • Anchorage, Alaska
  • +385 more
2022-03-22
Mar 22, 2022
N
Testing the Combination of the Anticancer Drugs ZEN003694 and Binimetinib in Patients With Advanced/Metastatic or Unresectable Solid Tumors With RAS Alterations and Triple Negative Breast Cancer
Recruiting
  • Advanced Malignant Solid Neoplasm
  • +4 more
  • Houston, Texas
    University of Texas MD Anderson Cancer Center LAO
2022-03-22
Mar 22, 2022
N
NCI COVID-19 in Cancer Patients, NCCAPS Study
Active, not recruiting
  • COVID-19 Infection
  • +3 more
  • Biospecimen Collection
  • +3 more
  • Birmingham, Alabama
  • +940 more
2022-03-19
Mar 19, 2022