Myelofibrosis Clinical Trials

STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS
LAST UPDATED
I
To Evaluate the Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis (LIMBER-313)
Recruiting
  • Myelofibrosis
  • +3 more
  • Anchorage, Alaska
  • +155 more
2022-04-06
Apr 6, 2022
I
Safety and Tolerability Study of INCB057643 in Participants With Myelofibrosis and Other Advanced Myeloid Neoplasms
Recruiting
  • Myelofibrosis
  • +5 more
  • Birmingham, Alabama
  • +26 more
2022-03-30
Mar 30, 2022
C
Phase 3 Study of Pelabresib (CPI-0610) in Myelofibrosis (MF) (MANIFEST-2)
Recruiting
  • Myelofibrosis
  • +3 more
  • Birmingham, Alabama
  • +92 more
2022-04-04
Apr 4, 2022
N
Reduced Intensity Conditioning Transplant Using Haploidentical Donors - 2020
Completed
  • Chronic Myelogenous Leukemia
  • +9 more
  • Atlanta, Georgia
    Northside Hospital
2022-04-04
Apr 4, 2022
S
A Study of Oral TP-3654 in Patients With Myelofibrosis
Recruiting
  • Myelofibrosis
  • Gainesville, Florida
  • +10 more
2022-04-04
Apr 4, 2022
T
Reduced-Intensity Conditioning for the Prevention of Treatment-Related Mortality in Patients Who Undergo a Hematopoietic Stem Cell Transplant
Recruiting
  • Acute Lymphoblastic Leukemia
  • +15 more
  • Hematopoietic Cell Transplantation
  • +7 more
  • Philadelphia, Pennsylvania
    Sidney Kimmel Cancer Center at Thomas Jefferson University
2022-04-01
Apr 1, 2022
I
To Assess the Safety, Tolerability and Efficacy of Itacitinib Immediate Release Tablets in Participants With Primary or Secondary Myelofibrosis Who Have Received Prior Ruxolitinib and/or Fedratinib Monotherapy (LIMBER-213)
Active, not recruiting
  • Myelofibrosis
  • +2 more
  • New Orleans, Louisiana
  • +20 more
2022-03-22
Mar 22, 2022
K
A Study to Evaluate Safety and Efficacy of Selinexor Versus Treatment of Physician's Choice in Participants With Previously Treated Myelofibrosis
Recruiting
  • Myelofibrosis
  • Pasadena, California
  • +14 more
2022-04-01
Apr 1, 2022
M
Hu8F4 in Treating Patients With Advanced Hematologic Malignancies
Recruiting
  • Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
  • +10 more
  • Anti-PR1/HLA-A2 Monoclonal Antibody Hu8F4
  • +2 more
  • Houston, Texas
    M D Anderson Cancer Center
2022-03-30
Mar 30, 2022
C
An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions
Recruiting
  • Myeloproliferative Disorders
  • +4 more
  • La Jolla, California
  • +149 more
2022-03-18
Mar 18, 2022
N
Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia
Active, not recruiting
  • Acute Myeloid Leukemia
  • +9 more
  • Los Angeles, California
  • +5 more
2022-03-30
Mar 30, 2022
C
An Efficacy and Safety Study of Fedratinib Compared to Best Available Therapy in Subjects With DIPSS-intermediate or High-risk Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, or Post-essential Thrombocythemia Myelofibrosis and Previously Treated With Ruxolitinib
Recruiting
  • Primary Myelofibrosis
  • +2 more
  • Darlinghurst, New South Wales, Australia
  • +109 more
2022-03-15
Mar 15, 2022
I
IMG-7289 in Patients With Myelofibrosis - 2022
Completed
  • Myelofibrosis
  • +3 more
  • Ann Arbor, Michigan
  • +4 more
2022-03-28
Mar 28, 2022
I
To Evaluate Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis Who Have Suboptimal Response to Ruxolitinib (LIMBER-304)
Recruiting
  • Myelofibrosis
  • +3 more
  • Berkeley, California
  • +178 more
2022-03-22
Mar 22, 2022
S
Myelofibrosis Treated With Pacritinib Before aSCT. (HOVON134MF)
Recruiting
  • Myelofibrosis
  • Antwerpen, Belgium
  • +11 more
2022-03-21
Mar 21, 2022
T
Study of TL-895 in Subjects With Myelofibrosis
Recruiting
  • Myelofibrosis
  • Aurora, Colorado
  • +63 more
2022-03-05
Mar 5, 2022
C
Prospective Assessment of Allogeneic Hematopoietic Cell Transplantation in Patients With Myelofibrosis
Recruiting
  • Myelofibrosis
  • Hematopoietic Stem Cell Transplant
  • Minneapolis, Minnesota
    Center for International Blood and Marrow Transplant Research
2022-03-17
Mar 17, 2022
R
Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer
Recruiting
  • Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
  • +36 more
  • Buffalo, New York
    Roswell Park Cancer Institute
2022-03-17
Mar 17, 2022
C
A Phase 2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Myelofibrosis
Recruiting
  • Myelofibrosis
  • +13 more
  • Phoenix, Arizona
  • +54 more
2022-03-04
Mar 4, 2022
K
Study to Evaluate KER-050 as a Monotherapy or in Combination With Ruxolitinib in Myelofibrosis
Recruiting
  • Myelofibrosis
  • KER-050 monotherapy
  • KER-050 in combination with ruxolitinib
  • Tweed Heads, New South Wales, Australia
  • +4 more
2022-03-02
Mar 2, 2022
F
Umbilical Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With Hematologic Disease
Recruiting
  • Acute Biphenotypic Leukemia
  • +18 more
  • Aurora, Colorado
  • +2 more
2022-03-02
Mar 2, 2022
G
A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment
Recruiting
  • Myelofibrosis
  • La Jolla, California
  • +169 more
2022-03-14
Mar 14, 2022
S
A Safety and Tolerability Study of Jaktinib
Not yet recruiting
  • Myelofibrosis
  • Jaktinib Hydrochloride Tablet
  • (no location specified)
2022-03-03
Mar 3, 2022
T
Phase 1b/2 Study of TL-895 Combined With Ruxolitinib in JAKi Treatment-Naïve MF Subjects and Subjects With MF Who Have a Suboptimal Response to Ruxolitinib
Not yet recruiting
  • Myelofibrosis
  • +3 more
  • (no location specified)
2022-03-05
Mar 5, 2022
I
A Rollover Study to Provide Continued Treatment for Participants Previously Enrolled in Studies of Itacitinib
Recruiting
  • Myelofibrosis
  • Aurora, Colorado
  • +4 more
2022-03-08
Mar 8, 2022