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144 items
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LAST UPDATED
A
Study to Assess the Bioequivalence of Acalabrutinib Tablet and Acalabrutinib Capsule - 2021
Completed
  • Bioequivalence
  • Treatment A: Acalabrutinib tablet
  • Treatment B: Acalabrutinib capsule
  • Glendale, California
  • +2 more
2021-06-01
Jun 1, 2021
U
A Pilot Study of Acalabrutinib in Relapsed/Refractory Primary and Secondary CNS Lymphomas
Recruiting
  • Central Nervous System Lymphoma
  • Chapel Hill, North Carolina
  • +1 more
2022-03-24
Mar 24, 2022
U
Acalabrutinib and Rituximab in Previously Untreated Mantle Cell Lymphoma
Not yet recruiting
  • Mantle Cell Lymphoma
  • (no location specified)
2021-08-04
Aug 4, 2021
W
Early Intervention With Acalabrutinib in Patients With High Risk CLL
Withdrawn
  • Chronic Lymphocytic Leukemia
  • CLL/SLL
  • Acalabrutinib
  • New York, New York
    Weill Cornell Medicine
2022-03-25
Mar 25, 2022
U
Acalabrutinib in Combination With R-CHOP for Previously Untreated Diffuse Large B-cell Lymphoma (DLBCL)
Recruiting
  • Diffuse Large B Cell Lymphoma
  • Colchester, Essex, United Kingdom
  • +2 more
2021-10-20
Oct 20, 2021
D
Rituximab and Acalabrutinib in Newly Diagnosed B Cell Post Transplant Lymphoproliferative Disorder
Recruiting
  • Post-transplant Lymphoproliferative Disorder
  • Cleveland, Ohio
    Cleveland Clinic, Case Comprehensive Cancer Center
2022-02-02
Feb 2, 2022
D
Acalabrutinib in CNSL
Recruiting
  • Central Nervous System Lymphoma
  • +2 more
  • Acalabrutinib
  • Boston, Massachusetts
  • +1 more
2022-01-05
Jan 5, 2022
A
A Study of Acalabrutinib in Combination With Rituximab + (Bendamustine or Venetoclax) in Subjects With MCL
Active, not recruiting
  • Mantle Cell Lymphoma (MCL)
  • Acalabrutinib in combination with BR
  • Acalabrutinib in combination with VR
  • Louisville, Kentucky
  • +14 more
2022-01-19
Jan 19, 2022
U
Acalabrutinib With R-CHOP in Previously Untreated Mantle Cell Lymphoma
Recruiting
  • Mantle Cell Lymphoma
  • Acalabrutinib
  • R-CHOP chemotherapy
  • Vancouver, British Columbia, Canada
  • +3 more
2022-03-17
Mar 17, 2022
W
Acalabrutinib With Bendamustine / Rituximab Followed by Cytarabine / Rituximab for Untreated Mantle Cell Lymphoma
Active, not recruiting
Has Results
  • Mantle Cell Lymphoma
  • Saint Louis, Missouri
    Washington University School of Medicine
2022-02-02
Feb 2, 2022
S
Acalabrutinib Plus RICE for Relapsed/Refractory DLBCL
Recruiting
  • Diffuse Large B Cell Lymphoma
  • Seattle, Washington
    Swedish Cancer Institute
2021-03-01
Mar 1, 2021
A
Acalabrutinib in Patients With Relapsed/Refractory and Treatment naïve Deletion 17p CLL/SLL
Active, not recruiting
Has Results
  • Chronic Lymphocytic Leukemia
  • Small Lymphocytic Lymphoma
  • Acalabrutinib (Arm A)
  • Acalabrutinib (Arm B)
  • Bethesda, Maryland
    Research Site
2022-01-19
Jan 19, 2022
A
A Study to Evaluate the Effect of Gastric pH on Acalabrutinib Pharmacokinetics (PK) in Healthy Adult Participants - 2016
Completed
  • Healthy Volunteers
  • Tempe, Arizona
    Celerion
2021-06-02
Jun 2, 2021
U
Acalabrutinib and High Frequency Low Dose Subcutaneous Rituximab in Patients With Previously Untreated Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma
Active, not recruiting
  • Chronic Lymphocytic Leukemia (CLL)
  • Small Lymphocytic Lymphoma (SLL)
  • Rochester, New York
    University of Rochester
2022-02-07
Feb 7, 2022
W
Acalabrutinib and Durvalumab in Primary and Secondary Central Nervous System Lymphoma
Recruiting
  • Primary Central Nervous System Lymphoma
  • Secondary Central Nervous System Lymphoma
  • Saint Louis, Missouri
    Washington University School of Medicine
2022-03-14
Mar 14, 2022
F
Acalabrutinib for the Treatment of Chronic Graft Versus Host Disease
Recruiting
  • Recurrent Moderate-Severe Chronic Graft Versus Host Disease
  • Hematopoietic and Lymphoid Cell Neoplasm
  • Acalabrutinib
  • Questionnaire Administration
  • Tampa, Florida
  • +3 more
2021-12-22
Dec 22, 2021
S
Acalabrutinib for GVHD Prophylaxis in Allogeneic Hematopoietic Stem Cell Transplantation in Lymphomas and Leukemia
Withdrawn
  • Lymphoma
  • Leukemia
  • Acalabrutinib, tacrolimus, methotrexate
  • (no location specified)
2022-02-20
Feb 20, 2022
A
A Study to Evaluate the Effect of Pharmacokinetics (PK) of Acalabrutinib and Its Active Metabolite (ACP-5862) When Administered Alone and With Moderate CYP3A4 Inhibitors Fluconazole or Isavuconazole in Healthy Adult Participants - 2020
Completed
  • Healthy Volunteers
  • Acalabrutinib
  • +2 more
  • Tempe, Arizona
    Celerion
2021-11-17
Nov 17, 2021
C
Acalabrutinib for the Treatment of Relapsed or Refractory Autoimmune Hemolytic Anemia in Patients With Chronic Lymphocytic Leukemia
Recruiting
  • Autoimmune Hemolytic Anemia
  • +3 more
  • Acalabrutinib
  • Duarte, California
    City of Hope Medical Center
2022-03-09
Mar 9, 2022
M
Acalabrutinib and Obinutuzumab for the Treatment of Chronic Lymphocytic Leukemia
Recruiting
  • Chronic Lymphocytic Leukemia
  • Small Lymphocytic Lymphoma
  • Acalabrutinib
  • Obinutuzumab
  • Houston, Texas
    M D Anderson Cancer Center
2021-11-18
Nov 18, 2021
A
A Study in Healthy Subjects to Assess Bioavailability (Proportion of a Drug Which Enters the Circulation to Have an Active Effect) of Acalabrutinib Tablet and Protonpump Inhibitor Effect (Members of a Class of Medications That Inhibits in Gastric Acid Production) for Rabeprazole - 2020
Completed
  • Mantle Cell Lymphoma
  • COVID-19
  • Acalabrutinib Treatment A
  • +3 more
  • Berlin, Germany
    Research Site
2020-12-28
Dec 28, 2020
J
Acalabrutinib Maintenance for the Treatment of Patients With Large B-cell Lymphoma
Not yet recruiting
  • Diffuse Large B-Cell Lymphoma
  • +3 more
  • Acalabrutinib
  • Los Angeles, California
  • +2 more
2022-03-17
Mar 17, 2022
F
Acalabrutinib in Combination With Venetoclax for the Treatment of Refractory or Recurrent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Not yet recruiting
  • Recurrent Chronic Lymphocytic Leukemia
  • +3 more
  • Seattle, Washington
    Fred Hutch/University of Washington Cancer Consortium
2022-03-31
Mar 31, 2022
A
Investigate the Influence of Severe Hepatic Impairment on the Pharmacokinetics of Acalabrutinib and Its Metabolite - 2019
Completed
Has Results
  • Hepatic Impairment
  • +2 more
  • acalabrutinib
  • Miami, Florida
  • +2 more
2021-08-16
Aug 16, 2021
A
A Study to Evaluate the Effect of an Acidic Formulation of Acalabrutinib (ACP-196), Acidic Beverage, or Grapefruit Juice on the Pharmacokinetics (PK) of ACP-196 Alone and Coadministered With Omeprazole - 2016
Completed
  • Healthy Volunteers
  • Lincoln, Nebraska
    Laura Sterling, MD, MPH
2021-05-05
May 5, 2021