Intervention of Air Pollution and Acute Coronary Syndrome
Study Details
Study Description
Brief Summary
To determine the effect of intervention of ambient air pollution on acute coronary syndrome patients.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
N/A |
Detailed Description
To investgate the effect of wearing facemasks to decreasing levels of exposure to ambient air on acute coronary syndrome patients.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Sham Comparator: no masking not wearing facemask |
Device: mask
facemask
|
Active Comparator: masking wearing facemask |
Device: mask
facemask
|
Outcome Measures
Primary Outcome Measures
- vascular function [six months]
Systolic blood pressure and diastolic blood pressure measured by omron HBP-1300
- autonomic nervous function [six months]
Twenty four-hour electrocardiograms and heart rate variability
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Non-smoker of any type during past six months and living in a non-smoking household.
-
A diagnosis of myocardial infarction or unstable angina 7-90 days prior to signed informed consent.
Exclusion Criteria:
-
Unstable CV disorders including uncompensated heart failure, refractory angina, uncontrolled arrhythmias, critical valvular heart disease and severe hypertension.
-
A history of infection with human immunodeficiency virus.
-
History of malignancy including leukemia and lymphoma AND/OR any severe, life-threatening disease AND/OR history of drug abuse within the last 2 years.
-
Pregnancy or intent to get pregnant during the study period.
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | Peking University ,School of Public Health | Beijing | Beijing | China | 100191 |
Sponsors and Collaborators
- Peking University
Investigators
- Principal Investigator: Wei Huang, PhD, Peking University Health Science Center
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- WeiHuang19