Anemia and Pneumonia

Sponsor

Assiut University (Other)

Overall Status

Not yet recruiting

CT.gov ID

NCT05586945

Collaborator

(none)

156

Enrollment

Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

Assess prevalence of anemia among pneumonic children aged two months up to two years.

Condition or Disease	Intervention/Treatment	Phase
Pneumonia

Detailed Description

Pneumonia is an infection via one or both lungs . bacteria and viruses are the most common causes. pneumonia can be medical emergency especially among high risk group like children less than five years Iron deficiency anemia is one of the major health problem in young children. It may be associated with increased risk of pneumonia (1).

A study conducted by Bhaskaram reported high frequency of anemia 83 % in children with pneumonia (2). Iron functions in the immune system are essential, among which are included: the maintenance of the activity of phagocyte oxidase, an iron excess can be used by bacteria to improve its growth (3). Anemia was found to be independently associated with fatal outcome in pneumonic children (4). The risk of development of pneumonia in children with anemia increases approximately by four times in comparison with children who have no anemic syndrome (5).

Breast-feeding protects against lower respiratory tract infection because of breast milk's unique antiinfective properties (6). Infants who were not being breast fed were 17 times more likely than those being breast fed without formula milk to be admitted to hospital for pneumonia (7). one of the factors that affects severe malnutrition is wrong parenting as parents can play an important role in their children's growth through proper, adequate feeding (8). There's no available studies that examine the association between anemia and pneumonia in our locality.

Study Design

Study Type:

Observational

Anticipated Enrollment :

156 participants

Observational Model:

Case-Only

Time Perspective:

Cross-Sectional

Official Title:

Association of Anemia With Pneumonia in Children up to Two Years Attending Assiut University Children 's Hospital .

Anticipated Study Start Date :

Jun 1, 2023

Anticipated Primary Completion Date :

Jun 1, 2024

Anticipated Study Completion Date :

Aug 1, 2024

Outcome Measures

Primary Outcome Measures

Determine association between anemia and pneumonia in children aged two months up to two years Secondary (subsidiary): Study other associated factors as nutrition and sociodemographic factors [6 months duration]

Eligibility Criteria

Criteria

Ages Eligible for Study:

2 Months to 2 Years

Sexes Eligible for Study:

All

Inclusion Criteria:

Inclusion criteria: Children aged two months up to two years who attend to Assiut University Hospital with pneumonia in the outpatient pediatric clinic, emergency unit and from inpatient .

Exclusion Criteria:

. Exclusion criteria: All patients with other comorbidities will be excluded from our study as: severe sepsis & localized infection e.g endocarditis, empyema, autoimmune diseases,renal diseases and congenital anomaly

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

Assiut University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Marwa Abd Ellatif Ahmed Mohamed, Association of anemia with pneumonia in children up to two years attending AssiutU university children hospital, Assiut University

ClinicalTrials.gov Identifier:

NCT05586945

Other Study ID Numbers:

anemia and pneumonia

First Posted:

Oct 19, 2022

Last Update Posted:

Oct 19, 2022

Last Verified:

Oct 1, 2022

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Additional relevant MeSH terms:

Pneumonia

Study Results

No Results Posted as of Oct 19, 2022