APOLLO: Personalized rehAbilitation PrOgram in aLLOgeneic Bone Marrow Transplantation

• Sponsor: University of Alberta (Other)
• Overall Status: Recruiting
• CT.gov ID: NCT05579678
• Collaborator: (none)
• Enrollment: 45
• Location: 1
• Anticipated Duration (Months): 19.3
• Patients Per Site Per Month: 2.3

Study Details

Study Description

Brief Summary

People who undergo allogeneic bone marrow transplant for blood cancers receive the highest chemotherapy doses possible that humans can receive and still survive. As a result, they have devastating side effects during the procedure and for many years afterwards. Damage to organs and muscles cause long-lasting physical weakness and the psychological experience is severe enough to be termed 'post traumatic stress disorder' that also lasts for many years. These effects are worsened by the fact that most Canadians live several hours away from treatment and transplant centers, leaving them entirely on their own to manage these difficult long term effects. The APOLLO team will perform a qualitative study to learn the experiences of people undergoing allogeneic bone marrow transplant while they receive access to a supportive care computer 'app' and telephone support from nursing, exercise and nutrition experts. In this way, the APOLLO team will learn the most helpful type and timing of supportive care from those who know best.

Condition or Disease	Intervention/Treatment	Phase
Allogeneic Disease	Behavioral: Supportive nursing, nutritional and physical activity with a handheld 'app'

Study Design

• Study Type: Observational
• Anticipated Enrollment: 45 participants
• Observational Model: Cohort
• Time Perspective: Prospective
• Official Title: APOLLO: Personalized rehAbilitation PrOgram in aLLOgeneic Bone Marrow Transplantation
• Actual Study Start Date: Nov 20, 2022
• Anticipated Primary Completion Date: Jun 30, 2024
• Anticipated Study Completion Date: Jun 30, 2024

Outcome Measures

Primary Outcome Measures

1. Title: Acceptability of a multimodal supportive care [1 year]

   Description: Questionnaire to assess usefulness of a multimodal supportive care App that includes care navigation (nursing, exercise, nutrition)

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 70 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• eligible for allogeneic transplantation

Exclusion Criteria:

• none

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	University of Alberta	Edmonton	Alberta	Canada	T6G 1C9

Sponsors and Collaborators

• University of Alberta

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: University of Alberta
• ClinicalTrials.gov Identifier: NCT05579678
• Other Study ID Numbers: HREBA.CC-22-0164
• First Posted: Oct 14, 2022
• Last Update Posted: Dec 2, 2022
• Last Verified: Sep 1, 2022

• Individual Participant Data (IPD) Sharing Statement: Undecided
• Plan to Share IPD: Undecided
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No

Study Results

No Results Posted as of Dec 2, 2022