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Pneucast: A Study to Assess the Impact of Pneumococcal Conjugate Vaccination Programme on the Carriage of Pneumococci

Sponsor
Public Health England (Other)
Overall Status
Completed
CT.gov ID
NCT01040143
Collaborator
(none)
450
Enrollment
3
Locations
26
Duration (Months)
150
Patients Per Site
5.8
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

A study taking swabs from the back of the nose (nasopharynx) to look at carriage of pneumococci.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    450 participants
    Observational Model:
    Case-Control
    Time Perspective:
    Cross-Sectional
    Official Title:
    A Study to Assess the Impact of Pneumococcal Conjugate Vaccination Programme on the Carriage of Pneumococci
    Study Start Date :
    Jan 1, 2008
    Actual Primary Completion Date :
    Mar 1, 2010
    Actual Study Completion Date :
    Mar 1, 2010

    Outcome Measures

    Primary Outcome Measures

    1. Presence of pneumococci in nasopharyngeal swabs []

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    1 Year and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:

    • Born in a cohort eligible for routine or catch up pneumococcal conjugate vaccination (i.e. date of birth since 4th September 2004) or a family member where a child is eligible and has been enrolled

    • Written informed consent given by the subject's parent/ legal guardian as well as assent from the child after the nature of the study has been explained to them or

    • Written informed consent given by the subject after the nature of the study has been explained to them

    Exclusion Criteria:

    • Moderate to severe disability.

    • Cerebral palsy, syndromes and neurological disorders affecting swallowing.

    • Ear Nose and Throat disorders affecting the anatomy of the ear,i.e.malformed ears.

    • Confirmed or suspected immunodeficiency (congenital or acquired).

    • On immunosuppressive therapy.

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Health Protection Agency Stevenage Hertfordshire United Kingdom
    2 Health Protection Agency Gloucester United Kingdom
    3 Health Protection Agency London United Kingdom NW9 5HT

    Sponsors and Collaborators

    • Public Health England

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Additional Information:

    Publications

    None provided.
    Responsible Party:
    , ,
    ClinicalTrials.gov Identifier:
    NCT01040143
    Other Study ID Numbers:
    • PneuCaSt
    First Posted:
    Dec 29, 2009
    Last Update Posted:
    Mar 22, 2019
    Last Verified:
    Sep 1, 2010
    Keywords provided by , ,
    Pneumococci
    Streptococcus pneumoniae
    Additional relevant MeSH terms:
    Pneumococcal Infections

    Study Results

    No Results Posted as of Mar 22, 2019