Association Between Pseudoexfoliation Syndrome and Diabetes Mellitus
Study Details
Study Description
Brief Summary
Pseudoexfoliation syndrome (PEX) is characterized by the deposition of a distinctive fibrillar material in the anterior segment of the eye and was first described in 1917 by Lindberg. It is frequently associated with open angle glaucoma, known as pseudoexfoliation glaucoma, which is one of the most common identifiable forms of secondary open angle glaucoma worldwide. Despite extensive research, the exactchemical nature of the fibrillar material is unknown. It is believed to be secreted multifocally in the iris pigment epithelium, the ciliary epithelium, and the peripheral anterior lens epithelium.
Condition or Disease | Intervention/Treatment | Phase |
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Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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study group includes patients who will be diagnosed with Pseudoexfoliation syndrome |
Device: slit lamp
Presence of white grayish exfoliation material on the anterior lens capsule and / or the pupillary margin.
Poor pupillary dilatation due to atrophy of the dilator pupillae muscle.
The presence of pseudoexfoliative material (PXF)in cilliary processes and zonules.
presence of PXF material scattered on corneal endothelium.
Flecks of the exfoliative material on the anterior chamber which leads to glaucoma.
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control group age matched controls who do not have Pseudoexfoliation syndrome |
Device: slit lamp
Presence of white grayish exfoliation material on the anterior lens capsule and / or the pupillary margin.
Poor pupillary dilatation due to atrophy of the dilator pupillae muscle.
The presence of pseudoexfoliative material (PXF)in cilliary processes and zonules.
presence of PXF material scattered on corneal endothelium.
Flecks of the exfoliative material on the anterior chamber which leads to glaucoma.
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Outcome Measures
Primary Outcome Measures
- the percentage of diabetic patients with pseudo-exfoliation syndrome [10 minutes]
slit lamp examination of all diabetic patients to get the percentage of those with pseudo-exfoliation syndrome
Eligibility Criteria
Criteria
Inclusion Criteria:
- Phakic patients presenting to Ophthalmology outpatient clinic Of Assiut University Hospital.
Exclusion Criteria:
- Patients with previous intraocular surgery.
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Assiut University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- PXSDM