Testing Cabozantinib in Patients With Advanced Pancreatic Neuroendocrine and Carcinoid Tumors
Study Details
Study Description
Brief Summary
This randomized phase III trial studies cabozantinib to see how well it works compared with placebo in treating patients with neuroendocrine or carcinoid tumors that have spread to other places in the body (advanced). Cabozantinib is a chemotherapy drug known as a tyrosine kinase inhibitor, and it targets specific tyrosine kinase receptors, that when blocked, may slow tumor growth.
Detailed Description
PRIMARY OBJECTIVES:
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To determine whether cabozantinib S-malate (cabozantinib) can significantly improve progression-free survival (PFS) compared to placebo in patients with advanced pancreatic neuroendocrine tumors (NET) whose disease has progressed after prior therapy.
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To determine whether cabozantinib can significantly improve progression-free survival (PFS) compared to placebo in patients with advanced carcinoid tumors whose disease has progressed after prior therapy.
SECONDARY OBJECTIVES:
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To determine whether cabozantinib can significantly improve overall survival (OS) compared to placebo in patients with advanced pancreatic NET whose disease has progressed after prior therapy.
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To determine whether cabozantinib can significantly improve overall survival (OS) compared to placebo in patients with advanced carcinoid tumors whose disease has progressed after prior therapy.
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To evaluate safety and tolerability of cabozantinib versus placebo in patients with advanced pancreatic NET using Common Terminology Criteria for Adverse Events (CTCAE) and Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE).
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To evaluate safety and tolerability of cabozantinib versus placebo in patients with advanced carcinoid tumors using CTCAE and PRO-CTCAE.
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To evaluate the overall radiographic response rate of cabozantinib versus placebo in patients with advanced pancreatic NET whose disease has progressed after prior therapy.
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To evaluate the overall radiographic response rate of cabozantinib versus placebo in patients with advanced carcinoid tumors whose disease has progressed after prior therapy.
OTHER OBJECTIVES:
- Results of the primary analysis will be examined for consistency, while taking into account the stratification factors and/or covariates of baseline quality of life (QOL) and fatigue.
QUALITY OF LIFE SUBSTUDY OBJECTIVES:
- To compare overall quality of life, disease-related symptoms, and other domains between the two treatment groups (cabozantinib versus [vs.] placebo) within each cohort of patients (pancreatic NET vs. carcinoid tumor). (Quality of Life Substudy Objective - A021602-HO1)
POPULATION PHARMACOKINETICS SUBSTUDY OBJECTIVES:
- To describe the population pharmacokinetic and exposure-response relationships of cabozantinib in patients with advanced neuroendocrine tumors.
OUTLINE: Patients are randomized to 1 of 2 arms.
ARM I: Patients receive cabozantinib S-malate orally (PO) once daily (QD) on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
ARM II: Patients receive placebo PO QD on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.
After completion of study treatment, patients are followed up every 12 weeks until disease progression or start of new anticancer therapy, and then every 6 months until 8 years after registration.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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Experimental: Arm I (cabozantinib S-malate) Patients receive cabozantinib S-malate PO QD on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. |
Drug: Cabozantinib S-malate
Given PO
Other Names:
Other: Laboratory Biomarker Analysis
Correlative studies
Other: Quality-of-Life Assessment
Ancillary studies
Other Names:
|
Placebo Comparator: Arm II (placebo) Patients receive placebo PO QD on days 1-28. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. |
Other: Laboratory Biomarker Analysis
Correlative studies
Other: Placebo Administration
Given PO
Other: Quality-of-Life Assessment
Ancillary studies
Other Names:
|
Outcome Measures
Primary Outcome Measures
- Progression-free survival (PFS) [From randomization to the first radiographic documentation of disease progression, or death from any cause, assessed for up to 8 years]
Will be assessed per Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 determined by retrospective independent central review. Will be compared between treatment arms using the stratified log rank test at one-sided level 0.025. The stratification factors will be used for the analysis. The hazard ratio (HR) for PFS will be estimated using a stratified Cox proportional hazards model, and the 95% confidence interval (CI) for the HR will be provided. Results from an unstratified analysis will also be provided. Kaplan-Meier methodology will be used to estimate the median PFS for each treatment arm, and Kaplan-Meier curves will be produced. Brookmeyer Crowley methodology will be used to construct the 95% CI for the median PFS for each treatment arm.
Secondary Outcome Measures
- Overall survival (OS) [From randomization to death, from any cause, assessed for up to 8 years]
The analyses for OS will follow intent-to-treat (ITT) principle and will be conducted separately within each cohort (pancreatic neuroendocrine tumor [NET] and carcinoid tumor). The distribution of OS will be estimated using the method of Kaplan-Meier. The median OS, along with the 95% CI, will be estimated by the two treatment groups. Overall survival will be compared between treatment arms using the stratified log-rank test at a one-sided cumulative 2.5% level of significance. The stratified Cox regression will be used to estimate the HR of OS, along with the 95% CI. A hierarchical approach will be used to control for family-wise type-I error rate, therefore OS will be formally statistically tested only if the primary efficacy endpoint, PFS, is statistically significantly different between the two treatment groups.
- Incidence of adverse events (AEs) graded according to the Common Terminology Criteria for Adverse Events (CTCAE) and Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) [Up to 8 years]
For CTCAE data, the frequency tables will be reviewed to determine the patterns. The overall adverse event rates will be compared between treatment groups using Chi-square test (or Fisher's exact test if the data in contingency table is sparse). PRO-CTCAE data will, at minimum, be analyzed similarly to CTCAE data. The initial analysis of each PRO-CTCAE item will use all available scores in an analysis which mirrors the approach used for the CTCAE data. Supplemental analysis will use model-based multiple imputation incorporating baseline patient characteristics and physician-rated performance status. CTCAE data may be incorporated as auxiliary data into multiple imputation models for AEs which are captured by both PRO-CTCAE and CTCAE. Results from supplemental analysis will be descriptively compared to the results of the initial analysis to assess the robustness of results to missing data. Additional analyses of PRO-CTCAE data beyond those specified above may be undertaken.
- Radiographic response rate [Up to 8 years]
Will be defined as the proportion of patients in each arm whose best response is either complete response (CR) or partial response (PR). Radiographic response rate for both cohorts: the analyses for radiographic response rate will follow the ITT principle and will be conducted separately within each cohort (pancreatic NET and carcinoid tumor). The proportion of patients with either CR or PR as their best response will be estimated using point estimates and 95% confidence intervals according to the methods in Duffy and Santner. Radiographic response rate will be compared between treatment arms using the 2-sample z-test to compare sample proportion at a one-sided 2.5% level of significance.
Eligibility Criteria
Criteria
Inclusion Criteria:
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Documentation of Disease:
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Histologic Documentation: Well- or moderately-differentiated neuroendocrine tumors of pancreatic and non-pancreatic (i.e. carcinoid) origin by local pathology
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The pathology report must state ONE of the following: 1) well- or moderately-differentiated neuroendocrine tumor, 2) low- or intermediate-grade neuroendocrine tumor, or 3) carcinoid tumor or atypical carcinoid tumor; documentation of histology from a primary or metastatic site is allowed
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Patients with poorly differentiated neuroendocrine carcinoma, high-grade neuroendocrine carcinoma, adenocarcinoid tumor, or goblet cell carcinoid tumor are not eligible
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Stage: Locally advanced/unresectable or metastatic disease
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Tumor Site: Histological documentation of neuroendocrine tumor of pancreatic, gastrointestinal (GI), lung, or unknown primary site; GI, lung, and unknown primary NETs will enroll in the carcinoid tumor cohort of the study
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Functional (associated with a clinical hormone syndrome) or nonfunctional tumors are allowed
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Radiologic Evaluation: Target lesions must have shown evidence of disease progression by Response Evaluation Criteria in Solid Tumors (RECIST) version (v)1.1 criteria in the 12 months prior to registration; the radiologic images, imaging reports, and clinic notes indicating growth of existing lesions, development of new lesions, or treatment changes must be submitted
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Measurable Disease
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Patients must have measurable disease per RECIST 1.1 by computer tomography (CT) scan or magnetic resonance imaging (MRI)
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Lesions must be accurately measured in at least one dimension (longest diameter to be recorded) as >= 1 cm with CT or MRI (or >= 1.5 cm for lymph nodes); non-measurable disease includes disease smaller than these dimensions or lesions considered truly non-measurable including: leptomeningeal disease, ascites, pleural or pericardial effusion, lymphangitic involvement of skin or lung
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Prior Treatment
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Patient must have experienced disease progression on or intolerance to treatment discontinuation of at least one Food and Drug Administration (FDA)-approved line of therapy (except somatostatin analogs); prior lins of therapy may include: everolimus, sunitinib, or lutetium Lu 177 dotatate in patients with pancreatic NET; everolimus in patients with lung NET; everolimus or lutetium Lu 177 dotatate in patients with gastrointestinal NET
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Prior treatment (except somatostatin analogs) with biologic therapy, immunotherapy, chemotherapy, investigational agent for malignancy, and/or radiation must be completed at least 28 days prior to registration
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Prior treatment with somatostatin analogs is allowed, and continuation of treatment with somatostatin analogs while on cabozantinib/placebo is allowed provided that the patient has been on a stable dose for at least two months
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Prior systemic treatment with radionuclide therapy must be completed at least 6 weeks prior to registration
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Prior treatment with hepatic artery embolization (including bland embolization, chemoembolization, and selective internal radiation therapy) or ablative therapies is allowed if measurable disease remains outside of the treated area or if there is documented disease progression in a treated site; prior liver-directed or other ablative treatment must be completed at least 28 days prior to registration
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Prior treatment with cabozantinib is not allowed
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Patients should have resolution of any toxic effects of prior therapy (except alopecia and fatigue) to National Cancer Institute (NCI) CTCAE, version 5.0, grade 1 or less
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Patients must have completed any major surgery at least 12 weeks prior to registration and any minor surgery (including uncomplicated tooth extractions) at least 28 days prior to registration; complete wound healing from major surgery must have occurred at least 28 days prior to registration, and complete wound healing from minor surgery must have occurred at least 10 days prior to registration
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Patient History
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No class III or IV congestive heart failure (CHF) within 6 months of registration
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No clinically significant cardiac arrhythmia within 6 months of registration
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No unstable angina or MI within 6 months of registration
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No thromboembolic events within 6 months of registration (including [incl.] stroke, transient ischemic attack [TIA], deep vein thrombosis [DVT], & pulmonary embolism [PE])
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No known history of congenital long QT syndrome
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No uncontrolled hypertension within 14 days of registration (defined as systolic blood pressure [SBP] >= 150 mmHg and/or diastolic blood pressure [DBP] >= 90 mmHg despite optimal medical management)
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No clinically significant GI bleeding within 6 months of registration
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No clinically significant gastrointestinal abnormalities that may increase the risk for gastrointestinal bleeding within 6 months of registration including, but not limited to: active peptic ulcer, known endoluminal metastatic lesion(s) with history of bleeding, inflammatory bowel disease, or other gastrointestinal conditions with increased risk of perforation
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No GI perforation within 6 months of registration
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No known tumor with invasion into the GI tract from the outside causing increased risk of perforation or bleeding within 28 days of registration
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No radiologic or clinical evidence of pancreatitis
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No known cavitary lung lesions
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No known endobronchial lesions involving the main or lobar bronchi and/or lesions infiltrating major pulmonary vessels that increase the risk of pulmonary hemorrhage; (CT with contrast is recommended to evaluate such lesions)
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No hemoptysis greater than 1/2 teaspoon (2.5 mL) or any other signs of pulmonary hemorrhage within the 3 months prior to registration
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No known tumor invading or encasing any major blood vessels
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No history of non-healing wounds or ulcers within 28 days of registration
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No history of fracture within 28 days of registration
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No brain metastases or cranial epidural disease unless adequately treated, stable, and off steroid support for at least 4 weeks prior to registration
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No known medical condition causing an inability to swallow oral formulations of agents
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No history of allergic reaction attributed to compounds of similar chemical or biological composition to cabozantinib/placebo
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No "currently active" second malignancy other than non-melanoma skin cancers or cervical carcinoma in situ; patients are not considered to have a "currently active" malignancy if they have completed therapy and are free of disease for >= 3 years
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Concomitant Medications
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Other planned concurrent investigational agents or other tumor directed therapies (chemotherapy, radiation) are not allowed while on this study
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Concurrent use of somatostatin analogs while on cabozantinib/placebo is allowed provided that the patient has been on a stable dose for at least two months
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Full dose oral anticoagulation/antiplatelet therapy is not permitted; low dose aspirin =< 81 mg/day is allowed; anticoagulation with therapeutic doses of low molecular weight heparin (LMWH) is allowed in patients who are on a stable dose of LMWH for at least 6 weeks prior to registration; treatment with warfarin is not allowed; anticoagulation in patients with brain metastases is not permitted
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Chronic concomitant treatment with strong inhibitors of CYP3A4 is not allowed; patients must discontinue the drug at least 14 days prior to registration on the study
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Chronic concomitant treatment with strong CYP3A4 inducers is not allowed; patients must discontinue the drug at least 14 days prior to the start of study treatment
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Not pregnant and not nursing
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Women of childbearing potential must have a negative pregnancy test done =< 14 days prior to registration
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A female of childbearing potential is a sexually mature female who: 1) has not undergone a hysterectomy or bilateral oophorectomy; or 2) has not been naturally postmenopausal for at least 12 consecutive months (i.e. has had menses at any time in the preceding 12 consecutive months)
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Eastern Cooperative Oncology Group (ECOG) performance status: 0-2
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Absolute neutrophil count (ANC) >= 1,500/mm^3
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Hemoglobin >= 9 g/dL
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Platelet count >= 100,000/mm^3
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Prothrombin time (PT)/ international normalized ratio (INR), partial thromboplastin time (PTT) < 1.3 x upper limit of normal (ULN)
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Aspartate aminotransferase (AST)/ alanine aminotransferase (ALT) =< 3 x ULN
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Total bilirubin =< 1.5 x ULN
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Except in the case of Gilbert disease, in which case total bilirubin must be =< 3 x ULN
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Creatinine =< 1.5 mg/dL OR creatinine clearance >= 45 mL/min
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Albumin >= 2.8 g/dL
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Potassium within normal limits (WNL)
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Supplementation is acceptable to achieve a value WNL; in patients with low albumin levels, a corrected calcium value WNL is acceptable; in patients with abnormal TSH, if free T4 is normal and patient is clinically euthyroid, patient is eligible
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Phosphorus WNL
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Supplementation is acceptable to achieve a value WNL; in patients with low albumin levels, a corrected calcium value WNL is acceptable; in patients with abnormal TSH, if free T4 is normal and patient is clinically euthyroid, patient is eligible
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Calcium WNL Phosphorus WNL
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Supplementation is acceptable to achieve a value WNL; in patients with low albumin levels, a corrected calcium value WNL is acceptable; in patients with abnormal TSH, if free T4 is normal and patient is clinically euthyroid, patient is eligible
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Magnesium WNL
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Supplementation is acceptable to achieve a value WNL; in patients with low albumin levels, a corrected calcium value WNL is acceptable; in patients with abnormal TSH, if free T4 is normal and patient is clinically euthyroid, patient is eligible
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Urine protein to creatinine (UPC) ratio =< 1
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QT interval corrected for heart rate using Fridericia's formula (QTcF) =< 500 msec
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Thyroid-stimulating hormone (TSH) WNL
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Supplementation is acceptable to achieve a TSH WNL; in patients with abnormal TSH, if free T4 is normal and patient is clinically euthyroid, patient is eligible
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Katmai Oncology Group | Anchorage | Alaska | United States | 99508 |
2 | Kingman Regional Medical Center | Kingman | Arizona | United States | 86401 |
3 | Banner University Medical Center - Tucson | Tucson | Arizona | United States | 85719 |
4 | University of Arizona Cancer Center-North Campus | Tucson | Arizona | United States | 85719 |
5 | University of Arkansas for Medical Sciences | Little Rock | Arkansas | United States | 72205 |
6 | Kaiser Permanente-Deer Valley Medical Center | Antioch | California | United States | 94531 |
7 | PCR Oncology | Arroyo Grande | California | United States | 93420 |
8 | Sutter Auburn Faith Hospital | Auburn | California | United States | 95602 |
9 | Alta Bates Summit Medical Center-Herrick Campus | Berkeley | California | United States | 94704 |
10 | Mills-Peninsula Medical Center | Burlingame | California | United States | 94010 |
11 | City of Hope Comprehensive Cancer Center | Duarte | California | United States | 91010 |
12 | Epic Care-Dublin | Dublin | California | United States | 94568 |
13 | Epic Care Partners in Cancer Care | Emeryville | California | United States | 94608 |
14 | Kaiser Permanente-Fremont | Fremont | California | United States | 94538 |
15 | Palo Alto Medical Foundation-Fremont | Fremont | California | United States | 94538 |
16 | Kaiser Permanente-Fresno | Fresno | California | United States | 93720 |
17 | Contra Costa Regional Medical Center | Martinez | California | United States | 94553-3156 |
18 | Fremont - Rideout Cancer Center | Marysville | California | United States | 95901 |
19 | Memorial Medical Center | Modesto | California | United States | 95355 |
20 | Kaiser Permanente-Modesto | Modesto | California | United States | 95356 |
21 | Palo Alto Medical Foundation-Camino Division | Mountain View | California | United States | 94040 |
22 | Alta Bates Summit Medical Center - Summit Campus | Oakland | California | United States | 94609 |
23 | Kaiser Permanente-Oakland | Oakland | California | United States | 94611 |
24 | Palo Alto Medical Foundation Health Care | Palo Alto | California | United States | 94301 |
25 | Stanford Cancer Institute Palo Alto | Palo Alto | California | United States | 94304 |
26 | Kaiser Permanente-Redwood City | Redwood City | California | United States | 94063 |
27 | Kaiser Permanente-Richmond | Richmond | California | United States | 94801 |
28 | Kaiser Permanente-Roseville | Roseville | California | United States | 95661 |
29 | Sutter Roseville Medical Center | Roseville | California | United States | 95661 |
30 | Kaiser Permanente Downtown Commons | Sacramento | California | United States | 95814 |
31 | Sutter Medical Center Sacramento | Sacramento | California | United States | 95816 |
32 | University of California Davis Comprehensive Cancer Center | Sacramento | California | United States | 95817 |
33 | Kaiser Permanente-South Sacramento | Sacramento | California | United States | 95823 |
34 | Salinas Valley Memorial | Salinas | California | United States | 93901 |
35 | California Pacific Medical Center-Pacific Campus | San Francisco | California | United States | 94115 |
36 | Kaiser Permanente-San Francisco | San Francisco | California | United States | 94115 |
37 | UCSF Medical Center-Mission Bay | San Francisco | California | United States | 94158 |
38 | Kaiser Permanente-Santa Teresa-San Jose | San Jose | California | United States | 95119 |
39 | Kaiser Permanente San Leandro | San Leandro | California | United States | 94577 |
40 | Mills Health Center | San Mateo | California | United States | 94401 |
41 | Kaiser Permanente-San Rafael | San Rafael | California | United States | 94903 |
42 | Kaiser San Rafael-Gallinas | San Rafael | California | United States | 94903 |
43 | Kaiser Permanente Medical Center - Santa Clara | Santa Clara | California | United States | 95051 |
44 | Palo Alto Medical Foundation-Santa Cruz | Santa Cruz | California | United States | 95065 |
45 | Kaiser Permanente-Santa Rosa | Santa Rosa | California | United States | 95403 |
46 | Kaiser Permanente-South San Francisco | South San Francisco | California | United States | 94080 |
47 | Kaiser Permanente-Stockton | Stockton | California | United States | 95210 |
48 | Palo Alto Medical Foundation-Sunnyvale | Sunnyvale | California | United States | 94086 |
49 | Kaiser Permanente Medical Center-Vacaville | Vacaville | California | United States | 95688 |
50 | Kaiser Permanente-Vallejo | Vallejo | California | United States | 94589 |
51 | Sutter Solano Medical Center/Cancer Center | Vallejo | California | United States | 94589 |
52 | Kaiser Permanente-Walnut Creek | Walnut Creek | California | United States | 94596 |
53 | Rocky Mountain Cancer Centers-Aurora | Aurora | Colorado | United States | 80012 |
54 | Rocky Mountain Cancer Centers-Boulder | Boulder | Colorado | United States | 80304 |
55 | Penrose-Saint Francis Healthcare | Colorado Springs | Colorado | United States | 80907 |
56 | National Jewish Health-Main Campus | Denver | Colorado | United States | 80206 |
57 | Rocky Mountain Cancer Centers-Midtown | Denver | Colorado | United States | 80218 |
58 | SCL Health Saint Joseph Hospital | Denver | Colorado | United States | 80218 |
59 | Rocky Mountain Cancer Centers-Rose | Denver | Colorado | United States | 80220 |
60 | Mountain Blue Cancer Care Center - Swedish | Englewood | Colorado | United States | 80113 |
61 | Swedish Medical Center | Englewood | Colorado | United States | 80113 |
62 | National Jewish Health-Western Hematology Oncology | Golden | Colorado | United States | 80401 |
63 | Saint Mary's Hospital and Regional Medical Center | Grand Junction | Colorado | United States | 81501 |
64 | North Colorado Medical Center | Greeley | Colorado | United States | 80631 |
65 | Good Samaritan Medical Center | Lafayette | Colorado | United States | 80026 |
66 | Rocky Mountain Cancer Centers-Littleton | Littleton | Colorado | United States | 80120 |
67 | Rocky Mountain Cancer Centers-Sky Ridge | Lone Tree | Colorado | United States | 80124 |
68 | McKee Medical Center | Loveland | Colorado | United States | 80539 |
69 | National Jewish Health-Northern Hematology Oncology | Thornton | Colorado | United States | 80260 |
70 | SCL Health Lutheran Medical Center | Wheat Ridge | Colorado | United States | 80033 |
71 | Danbury Hospital | Danbury | Connecticut | United States | 06810 |
72 | Norwalk Hospital | Norwalk | Connecticut | United States | 06856 |
73 | MedStar Georgetown University Hospital | Washington | District of Columbia | United States | 20007 |
74 | GenesisCare USA - Aventura FP | Aventura | Florida | United States | 33180 |
75 | GenesisCare USA - Aventura | Aventura | Florida | United States | 33180 |
76 | GenesisCare USA - Boca Ration FP06 | Boca Raton | Florida | United States | 33431 |
77 | Regional Cancer Center-Lee Memorial Health System | Fort Myers | Florida | United States | 33905 |
78 | Memorial Regional Hospital/Joe DiMaggio Children's Hospital | Hollywood | Florida | United States | 33021 |
79 | Moffitt Cancer Center | Tampa | Florida | United States | 33612 |
80 | Emory University Hospital Midtown | Atlanta | Georgia | United States | 30308 |
81 | Emory University Hospital/Winship Cancer Institute | Atlanta | Georgia | United States | 30322 |
82 | Emory Saint Joseph's Hospital | Atlanta | Georgia | United States | 30342 |
83 | Hawaii Cancer Care - Savio | 'Aiea | Hawaii | United States | 96701 |
84 | Pali Momi Medical Center | 'Aiea | Hawaii | United States | 96701 |
85 | Hawaii Cancer Care Inc - Waterfront Plaza | Honolulu | Hawaii | United States | 96813 |
86 | Queen's Cancer Cenrer - POB I | Honolulu | Hawaii | United States | 96813 |
87 | Queen's Medical Center | Honolulu | Hawaii | United States | 96813 |
88 | Straub Clinic and Hospital | Honolulu | Hawaii | United States | 96813 |
89 | Queen's Cancer Center - Kuakini | Honolulu | Hawaii | United States | 96817 |
90 | Kaiser Permanente Moanalua Medical Center | Honolulu | Hawaii | United States | 96819 |
91 | Saint Alphonsus Cancer Care Center-Boise | Boise | Idaho | United States | 83706 |
92 | Saint Luke's Cancer Institute - Boise | Boise | Idaho | United States | 83712 |
93 | Saint Alphonsus Cancer Care Center-Caldwell | Caldwell | Idaho | United States | 83605 |
94 | Kootenai Health - Coeur d'Alene | Coeur d'Alene | Idaho | United States | 83814 |
95 | Walter Knox Memorial Hospital | Emmett | Idaho | United States | 83617 |
96 | Saint Luke's Cancer Institute - Fruitland | Fruitland | Idaho | United States | 83619 |
97 | Idaho Urologic Institute-Meridian | Meridian | Idaho | United States | 83642 |
98 | Saint Luke's Cancer Institute - Meridian | Meridian | Idaho | United States | 83642 |
99 | Saint Alphonsus Medical Center-Nampa | Nampa | Idaho | United States | 83686 |
100 | Saint Luke's Cancer Institute - Nampa | Nampa | Idaho | United States | 83686 |
101 | Kootenai Clinic Cancer Services - Post Falls | Post Falls | Idaho | United States | 83854 |
102 | Kootenai Cancer Clinic | Sandpoint | Idaho | United States | 83864 |
103 | Saint Luke's Cancer Institute - Twin Falls | Twin Falls | Idaho | United States | 83301 |
104 | Illinois CancerCare-Bloomington | Bloomington | Illinois | United States | 61704 |
105 | Illinois CancerCare-Canton | Canton | Illinois | United States | 61520 |
106 | Illinois CancerCare-Carthage | Carthage | Illinois | United States | 62321 |
107 | University of Illinois | Chicago | Illinois | United States | 60612 |
108 | University of Chicago Comprehensive Cancer Center | Chicago | Illinois | United States | 60637 |
109 | Carle on Vermilion | Danville | Illinois | United States | 61832 |
110 | Cancer Care Specialists of Illinois - Decatur | Decatur | Illinois | United States | 62526 |
111 | Illinois CancerCare-Dixon | Dixon | Illinois | United States | 61021 |
112 | Carle Physician Group-Effingham | Effingham | Illinois | United States | 62401 |
113 | Crossroads Cancer Center | Effingham | Illinois | United States | 62401 |
114 | Illinois CancerCare-Eureka | Eureka | Illinois | United States | 61530 |
115 | Illinois CancerCare-Galesburg | Galesburg | Illinois | United States | 61401 |
116 | Illinois CancerCare-Kewanee Clinic | Kewanee | Illinois | United States | 61443 |
117 | Illinois CancerCare-Macomb | Macomb | Illinois | United States | 61455 |
118 | Carle Physician Group-Mattoon/Charleston | Mattoon | Illinois | United States | 61938 |
119 | Loyola University Medical Center | Maywood | Illinois | United States | 60153 |
120 | UC Comprehensive Cancer Center at Silver Cross | New Lenox | Illinois | United States | 60451 |
121 | Cancer Care Center of O'Fallon | O'Fallon | Illinois | United States | 62269 |
122 | University of Chicago Medicine-Orland Park | Orland Park | Illinois | United States | 60462 |
123 | Illinois CancerCare-Ottawa Clinic | Ottawa | Illinois | United States | 61350 |
124 | Illinois CancerCare-Pekin | Pekin | Illinois | United States | 61554 |
125 | Illinois CancerCare-Peoria | Peoria | Illinois | United States | 61615 |
126 | Illinois CancerCare-Peru | Peru | Illinois | United States | 61354 |
127 | Illinois CancerCare-Princeton | Princeton | Illinois | United States | 61356 |
128 | Southern Illinois University School of Medicine | Springfield | Illinois | United States | 62702 |
129 | Springfield Clinic | Springfield | Illinois | United States | 62702 |
130 | Carle Cancer Center | Urbana | Illinois | United States | 61801 |
131 | Illinois CancerCare - Washington | Washington | Illinois | United States | 61571 |
132 | Memorial Hospital of South Bend | South Bend | Indiana | United States | 46601 |
133 | University of Iowa Healthcare Cancer Services Quad Cities | Bettendorf | Iowa | United States | 52722 |
134 | Mercy Hospital | Cedar Rapids | Iowa | United States | 52403 |
135 | Oncology Associates at Mercy Medical Center | Cedar Rapids | Iowa | United States | 52403 |
136 | Medical Oncology and Hematology Associates-West Des Moines | Clive | Iowa | United States | 50325 |
137 | Mercy Cancer Center-West Lakes | Clive | Iowa | United States | 50325 |
138 | Greater Regional Medical Center | Creston | Iowa | United States | 50801 |
139 | Iowa Methodist Medical Center | Des Moines | Iowa | United States | 50309 |
140 | Medical Oncology and Hematology Associates-Des Moines | Des Moines | Iowa | United States | 50309 |
141 | Broadlawns Medical Center | Des Moines | Iowa | United States | 50314 |
142 | Medical Oncology and Hematology Associates-Laurel | Des Moines | Iowa | United States | 50314 |
143 | Mercy Medical Center - Des Moines | Des Moines | Iowa | United States | 50314 |
144 | Trinity Regional Medical Center | Fort Dodge | Iowa | United States | 50501 |
145 | University of Iowa/Holden Comprehensive Cancer Center | Iowa City | Iowa | United States | 52242 |
146 | Mercy Medical Center-West Lakes | West Des Moines | Iowa | United States | 50266 |
147 | University of Kentucky/Markey Cancer Center | Lexington | Kentucky | United States | 40536 |
148 | LSU Health Baton Rouge-North Clinic | Baton Rouge | Louisiana | United States | 70805 |
149 | Our Lady of The Lake | Baton Rouge | Louisiana | United States | 70808 |
150 | Louisiana Hematology Oncology Associates LLC | Baton Rouge | Louisiana | United States | 70809 |
151 | Mary Bird Perkins Cancer Center | Baton Rouge | Louisiana | United States | 70809 |
152 | Our Lady of the Lake Physicians Group - Medical Oncology | Baton Rouge | Louisiana | United States | 70809 |
153 | Northshore Oncology Associates-Covington | Covington | Louisiana | United States | 70433 |
154 | Oncology Center of The South Incorporated | Houma | Louisiana | United States | 70360 |
155 | Brigham and Women's Hospital | Boston | Massachusetts | United States | 02115 |
156 | Boston Medical Center | Boston | Massachusetts | United States | 02118 |
157 | Beth Israel Deaconess Medical Center | Boston | Massachusetts | United States | 02215 |
158 | Dana-Farber Cancer Institute | Boston | Massachusetts | United States | 02215 |
159 | Lahey Hospital and Medical Center | Burlington | Massachusetts | United States | 01805 |
160 | Hickman Cancer Center | Adrian | Michigan | United States | 49221 |
161 | Saint Joseph Mercy Hospital | Ann Arbor | Michigan | United States | 48106 |
162 | University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | United States | 48109 |
163 | Bronson Battle Creek | Battle Creek | Michigan | United States | 49017 |
164 | Saint Joseph Mercy Brighton | Brighton | Michigan | United States | 48114 |
165 | Trinity Health IHA Medical Group Hematology Oncology - Brighton | Brighton | Michigan | United States | 48114 |
166 | Saint Joseph Mercy Canton | Canton | Michigan | United States | 48188 |
167 | Trinity Health IHA Medical Group Hematology Oncology - Canton | Canton | Michigan | United States | 48188 |
168 | Caro Cancer Center | Caro | Michigan | United States | 48723 |
169 | Saint Joseph Mercy Chelsea | Chelsea | Michigan | United States | 48118 |
170 | Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital | Chelsea | Michigan | United States | 48118 |
171 | Hematology Oncology Consultants-Clarkston | Clarkston | Michigan | United States | 48346 |
172 | McLaren Cancer Institute-Clarkston | Clarkston | Michigan | United States | 48346 |
173 | Newland Medical Associates-Clarkston | Clarkston | Michigan | United States | 48346 |
174 | Wayne State University/Karmanos Cancer Institute | Detroit | Michigan | United States | 48201 |
175 | Henry Ford Hospital | Detroit | Michigan | United States | 48202 |
176 | Ascension Saint John Hospital | Detroit | Michigan | United States | 48236 |
177 | Great Lakes Cancer Management Specialists-Doctors Park | East China Township | Michigan | United States | 48054 |
178 | Weisberg Cancer Treatment Center | Farmington Hills | Michigan | United States | 48334 |
179 | Genesee Cancer and Blood Disease Treatment Center | Flint | Michigan | United States | 48503 |
180 | Genesee Hematology Oncology PC | Flint | Michigan | United States | 48503 |
181 | Genesys Hurley Cancer Institute | Flint | Michigan | United States | 48503 |
182 | Hurley Medical Center | Flint | Michigan | United States | 48503 |
183 | McLaren Cancer Institute-Flint | Flint | Michigan | United States | 48532 |
184 | Singh and Arora Hematology Oncology PC | Flint | Michigan | United States | 48532 |
185 | Academic Hematology Oncology Specialists | Grosse Pointe Woods | Michigan | United States | 48236 |
186 | Great Lakes Cancer Management Specialists-Van Elslander Cancer Center | Grosse Pointe Woods | Michigan | United States | 48236 |
187 | Michigan Breast Specialists-Grosse Pointe Woods | Grosse Pointe Woods | Michigan | United States | 48236 |
188 | Bronson Methodist Hospital | Kalamazoo | Michigan | United States | 49007 |
189 | West Michigan Cancer Center | Kalamazoo | Michigan | United States | 49007 |
190 | Ascension Borgess Cancer Center | Kalamazoo | Michigan | United States | 49009 |
191 | Karmanos Cancer Institute at McLaren Greater Lansing | Lansing | Michigan | United States | 48910 |
192 | Sparrow Hospital | Lansing | Michigan | United States | 48912 |
193 | Hope Cancer Clinic | Livonia | Michigan | United States | 48154 |
194 | Trinity Health Saint Mary Mercy Livonia Hospital | Livonia | Michigan | United States | 48154 |
195 | Great Lakes Cancer Management Specialists-Macomb Medical Campus | Macomb | Michigan | United States | 48044 |
196 | Michigan Breast Specialists-Macomb Township | Macomb | Michigan | United States | 48044 |
197 | Saint Mary's Oncology/Hematology Associates of Marlette | Marlette | Michigan | United States | 48453 |
198 | Toledo Clinic Cancer Centers-Monroe | Monroe | Michigan | United States | 48162 |
199 | McLaren Cancer Institute-Macomb | Mount Clemens | Michigan | United States | 48043 |
200 | McLaren Cancer Institute-Central Michigan | Mount Pleasant | Michigan | United States | 48858 |
201 | McLaren Cancer Institute-Northern Michigan | Petoskey | Michigan | United States | 49770 |
202 | 21st Century Oncology-Pontiac | Pontiac | Michigan | United States | 48341 |
203 | Hope Cancer Center | Pontiac | Michigan | United States | 48341 |
204 | Newland Medical Associates-Pontiac | Pontiac | Michigan | United States | 48341 |
205 | Saint Joseph Mercy Oakland | Pontiac | Michigan | United States | 48341 |
206 | Huron Medical Center PC | Port Huron | Michigan | United States | 48060 |
207 | Lake Huron Medical Center | Port Huron | Michigan | United States | 48060 |
208 | McLaren-Port Huron | Port Huron | Michigan | United States | 48060 |
209 | Great Lakes Cancer Management Specialists-Rochester Hills | Rochester Hills | Michigan | United States | 48309 |
210 | Ascension Saint Mary's Hospital | Saginaw | Michigan | United States | 48601 |
211 | Oncology Hematology Associates of Saginaw Valley PC | Saginaw | Michigan | United States | 48604 |
212 | Bhadresh Nayak MD PC-Sterling Heights | Sterling Heights | Michigan | United States | 48312 |
213 | Ascension Saint Joseph Hospital | Tawas City | Michigan | United States | 48764 |
214 | Advanced Breast Care Center PLLC | Warren | Michigan | United States | 48088 |
215 | Great Lakes Cancer Management Specialists-Macomb Professional Building | Warren | Michigan | United States | 48093 |
216 | Macomb Hematology Oncology PC | Warren | Michigan | United States | 48093 |
217 | Michigan Breast Specialists-Warren | Warren | Michigan | United States | 48093 |
218 | Saint John Macomb-Oakland Hospital | Warren | Michigan | United States | 48093 |
219 | Saint Mary's Oncology/Hematology Associates of West Branch | West Branch | Michigan | United States | 48661 |
220 | Huron Gastroenterology PC | Ypsilanti | Michigan | United States | 48106 |
221 | Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus | Ypsilanti | Michigan | United States | 48197 |
222 | Sanford Joe Lueken Cancer Center | Bemidji | Minnesota | United States | 56601 |
223 | Fairview Ridges Hospital | Burnsville | Minnesota | United States | 55337 |
224 | Minnesota Oncology - Burnsville | Burnsville | Minnesota | United States | 55337 |
225 | Mercy Hospital | Coon Rapids | Minnesota | United States | 55433 |
226 | Essentia Health - Deer River Clinic | Deer River | Minnesota | United States | 56636 |
227 | Essentia Health Cancer Center | Duluth | Minnesota | United States | 55805 |
228 | Fairview Southdale Hospital | Edina | Minnesota | United States | 55435 |
229 | Unity Hospital | Fridley | Minnesota | United States | 55432 |
230 | Essentia Health Hibbing Clinic | Hibbing | Minnesota | United States | 55746 |
231 | Fairview Clinics and Surgery Center Maple Grove | Maple Grove | Minnesota | United States | 55369 |
232 | Minnesota Oncology Hematology PA-Maplewood | Maplewood | Minnesota | United States | 55109 |
233 | Saint John's Hospital - Healtheast | Maplewood | Minnesota | United States | 55109 |
234 | Abbott-Northwestern Hospital | Minneapolis | Minnesota | United States | 55407 |
235 | Hennepin County Medical Center | Minneapolis | Minnesota | United States | 55415 |
236 | Health Partners Inc | Minneapolis | Minnesota | United States | 55454 |
237 | New Ulm Medical Center | New Ulm | Minnesota | United States | 56073 |
238 | North Memorial Medical Health Center | Robbinsdale | Minnesota | United States | 55422 |
239 | Mayo Clinic in Rochester | Rochester | Minnesota | United States | 55905 |
240 | Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota | United States | 55416 |
241 | Regions Hospital | Saint Paul | Minnesota | United States | 55101 |
242 | United Hospital | Saint Paul | Minnesota | United States | 55102 |
243 | Essentia Health Sandstone | Sandstone | Minnesota | United States | 55072 |
244 | Saint Francis Regional Medical Center | Shakopee | Minnesota | United States | 55379 |
245 | Lakeview Hospital | Stillwater | Minnesota | United States | 55082 |
246 | Essentia Health Virginia Clinic | Virginia | Minnesota | United States | 55792 |
247 | Ridgeview Medical Center | Waconia | Minnesota | United States | 55387 |
248 | Rice Memorial Hospital | Willmar | Minnesota | United States | 56201 |
249 | Minnesota Oncology Hematology PA-Woodbury | Woodbury | Minnesota | United States | 55125 |
250 | Fairview Lakes Medical Center | Wyoming | Minnesota | United States | 55092 |
251 | Parkland Health Center-Bonne Terre | Bonne Terre | Missouri | United States | 63628 |
252 | Saint Francis Medical Center | Cape Girardeau | Missouri | United States | 63703 |
253 | Siteman Cancer Center at West County Hospital | Creve Coeur | Missouri | United States | 63141 |
254 | Parkland Health Center - Farmington | Farmington | Missouri | United States | 63640 |
255 | Washington University School of Medicine | Saint Louis | Missouri | United States | 63110 |
256 | Siteman Cancer Center-South County | Saint Louis | Missouri | United States | 63129 |
257 | Missouri Baptist Medical Center | Saint Louis | Missouri | United States | 63131 |
258 | Siteman Cancer Center at Christian Hospital | Saint Louis | Missouri | United States | 63136 |
259 | Siteman Cancer Center at Saint Peters Hospital | Saint Peters | Missouri | United States | 63376 |
260 | Sainte Genevieve County Memorial Hospital | Sainte Genevieve | Missouri | United States | 63670 |
261 | Missouri Baptist Sullivan Hospital | Sullivan | Missouri | United States | 63080 |
262 | Missouri Baptist Outpatient Center-Sunset Hills | Sunset Hills | Missouri | United States | 63127 |
263 | Community Hospital of Anaconda | Anaconda | Montana | United States | 59711 |
264 | Billings Clinic Cancer Center | Billings | Montana | United States | 59101 |
265 | Saint Vincent Frontier Cancer Center | Billings | Montana | United States | 59102 |
266 | Bozeman Deaconess Hospital | Bozeman | Montana | United States | 59715 |
267 | Saint James Community Hospital and Cancer Treatment Center | Butte | Montana | United States | 59701 |
268 | Benefis Healthcare- Sletten Cancer Institute | Great Falls | Montana | United States | 59405 |
269 | Great Falls Clinic | Great Falls | Montana | United States | 59405 |
270 | Saint Peter's Community Hospital | Helena | Montana | United States | 59601 |
271 | Kalispell Regional Medical Center | Kalispell | Montana | United States | 59901 |
272 | Community Medical Hospital | Missoula | Montana | United States | 59804 |
273 | CHI Health Saint Francis | Grand Island | Nebraska | United States | 68803 |
274 | Nebraska Cancer Specialists/Oncology Hematology West PC - MECC | Omaha | Nebraska | United States | 68114 |
275 | Nebraska Methodist Hospital | Omaha | Nebraska | United States | 68114 |
276 | Carson Tahoe Regional Medical Center | Carson City | Nevada | United States | 89703 |
277 | Cancer and Blood Specialists-Henderson | Henderson | Nevada | United States | 89052 |
278 | Comprehensive Cancer Centers of Nevada - Henderson | Henderson | Nevada | United States | 89052 |
279 | Comprehensive Cancer Centers of Nevada-Horizon Ridge | Henderson | Nevada | United States | 89052 |
280 | Las Vegas Cancer Center-Henderson | Henderson | Nevada | United States | 89052 |
281 | OptumCare Cancer Care at Seven Hills | Henderson | Nevada | United States | 89052 |
282 | Comprehensive Cancer Centers of Nevada-Southeast Henderson | Henderson | Nevada | United States | 89074 |
283 | GenesisCare USA - Henderson | Henderson | Nevada | United States | 89074 |
284 | Desert West Surgery | Las Vegas | Nevada | United States | 89102 |
285 | OptumCare Cancer Care at Charleston | Las Vegas | Nevada | United States | 89102 |
286 | University Medical Center of Southern Nevada | Las Vegas | Nevada | United States | 89102 |
287 | Hope Cancer Care of Nevada | Las Vegas | Nevada | United States | 89103 |
288 | Cancer and Blood Specialists-Shadow | Las Vegas | Nevada | United States | 89106 |
289 | Radiation Oncology Centers of Nevada Central | Las Vegas | Nevada | United States | 89106 |
290 | GenesisCare USA - Las Vegas | Las Vegas | Nevada | United States | 89109 |
291 | HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway | Las Vegas | Nevada | United States | 89109 |
292 | HealthCare Partners Medical Group Oncology/Hematology-San Martin | Las Vegas | Nevada | United States | 89113 |
293 | Radiation Oncology Centers of Nevada Southeast | Las Vegas | Nevada | United States | 89119 |
294 | Cancer Therapy and Integrative Medicine | Las Vegas | Nevada | United States | 89121 |
295 | Ann M Wierman MD LTD | Las Vegas | Nevada | United States | 89128 |
296 | Cancer and Blood Specialists-Tenaya | Las Vegas | Nevada | United States | 89128 |
297 | Comprehensive Cancer Centers of Nevada - Northwest | Las Vegas | Nevada | United States | 89128 |
298 | GenesisCare USA - Vegas Tenaya | Las Vegas | Nevada | United States | 89128 |
299 | HealthCare Partners Medical Group Oncology/Hematology-Tenaya | Las Vegas | Nevada | United States | 89128 |
300 | OptumCare Cancer Care at MountainView | Las Vegas | Nevada | United States | 89128 |
301 | Comprehensive Cancer Centers of Nevada-Summerlin | Las Vegas | Nevada | United States | 89144 |
302 | Summerlin Hospital Medical Center | Las Vegas | Nevada | United States | 89144 |
303 | Las Vegas Cancer Center-Medical Center | Las Vegas | Nevada | United States | 89148-2405 |
304 | Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | United States | 89148 |
305 | GenesisCare USA - Fort Apache | Las Vegas | Nevada | United States | 89148 |
306 | OptumCare Cancer Care at Fort Apache | Las Vegas | Nevada | United States | 89148 |
307 | HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills | Las Vegas | Nevada | United States | 89149 |
308 | Comprehensive Cancer Centers of Nevada - Central Valley | Las Vegas | Nevada | United States | 89169 |
309 | University Cancer Center | Las Vegas | Nevada | United States | 89169 |
310 | Hope Cancer Care of Nevada-Pahrump | Pahrump | Nevada | United States | 89048 |
311 | Renown Regional Medical Center | Reno | Nevada | United States | 89502 |
312 | Saint Mary's Regional Medical Center | Reno | Nevada | United States | 89503 |
313 | Radiation Oncology Associates | Reno | Nevada | United States | 89509 |
314 | Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | United States | 03756 |
315 | Memorial Sloan Kettering Basking Ridge | Basking Ridge | New Jersey | United States | 07920 |
316 | Englewood Hospital and Medical Center | Englewood | New Jersey | United States | 07631 |
317 | Memorial Sloan Kettering Monmouth | Middletown | New Jersey | United States | 07748 |
318 | Memorial Sloan Kettering Bergen | Montvale | New Jersey | United States | 07645 |
319 | The Valley Hospital-Luckow Pavilion | Paramus | New Jersey | United States | 07652 |
320 | Valley Hospital | Ridgewood | New Jersey | United States | 07450 |
321 | Valley Medical Group - Wayne Multispecialty Practice | Wayne | New Jersey | United States | 07470 |
322 | University of New Mexico Cancer Center | Albuquerque | New Mexico | United States | 87102 |
323 | New Mexico Oncology Hematology Consultants | Albuquerque | New Mexico | United States | 87109 |
324 | Presbyterian Kaseman Hospital | Albuquerque | New Mexico | United States | 87110 |
325 | Presbyterian Rust Medical Center/Jorgensen Cancer Center | Rio Rancho | New Mexico | United States | 87124 |
326 | Hematology Oncology Associates of Central New York-Auburn | Auburn | New York | United States | 13021 |
327 | Roswell Park Cancer Institute | Buffalo | New York | United States | 14263 |
328 | Memorial Sloan Kettering Commack | Commack | New York | United States | 11725 |
329 | Hematology Oncology Associates of Central New York-East Syracuse | East Syracuse | New York | United States | 13057 |
330 | Memorial Sloan Kettering Westchester | Harrison | New York | United States | 10604 |
331 | Mount Sinai Hospital | New York | New York | United States | 10029 |
332 | Memorial Sloan Kettering Cancer Center | New York | New York | United States | 10065 |
333 | University of Rochester | Rochester | New York | United States | 14642 |
334 | Hematology Oncology Associates of Central New York-Onondaga Hill | Syracuse | New York | United States | 13215 |
335 | Memorial Sloan Kettering Nassau | Uniondale | New York | United States | 11553 |
336 | UNC Lineberger Comprehensive Cancer Center | Chapel Hill | North Carolina | United States | 27599 |
337 | Southeastern Medical Oncology Center-Clinton | Clinton | North Carolina | United States | 28328 |
338 | Southeastern Medical Oncology Center-Goldsboro | Goldsboro | North Carolina | United States | 27534 |
339 | Margaret R Pardee Memorial Hospital | Hendersonville | North Carolina | United States | 28791 |
340 | Southeastern Medical Oncology Center-Jacksonville | Jacksonville | North Carolina | United States | 28546 |
341 | Vidant Oncology-Kinston | Kinston | North Carolina | United States | 28501 |
342 | Marion L Shepard Cancer Center at Vidant Beaufort Hospital | Washington | North Carolina | United States | 27889 |
343 | Sanford Bismarck Medical Center | Bismarck | North Dakota | United States | 58501 |
344 | Sanford Broadway Medical Center | Fargo | North Dakota | United States | 58122 |
345 | Sanford Roger Maris Cancer Center | Fargo | North Dakota | United States | 58122 |
346 | UHHS-Chagrin Highlands Medical Center | Beachwood | Ohio | United States | 44122 |
347 | Strecker Cancer Center-Belpre | Belpre | Ohio | United States | 45714 |
348 | Adena Regional Medical Center | Chillicothe | Ohio | United States | 45601 |
349 | Case Western Reserve University | Cleveland | Ohio | United States | 44106 |
350 | Ohio State University Comprehensive Cancer Center | Columbus | Ohio | United States | 43210 |
351 | Columbus Oncology and Hematology Associates Inc | Columbus | Ohio | United States | 43214 |
352 | Grant Medical Center | Columbus | Ohio | United States | 43215 |
353 | The Mark H Zangmeister Center | Columbus | Ohio | United States | 43219 |
354 | Doctors Hospital | Columbus | Ohio | United States | 43228 |
355 | Delaware Health Center-Grady Cancer Center | Delaware | Ohio | United States | 43015 |
356 | OhioHealth Mansfield Hospital | Mansfield | Ohio | United States | 44903 |
357 | Marietta Memorial Hospital | Marietta | Ohio | United States | 45750 |
358 | OhioHealth Marion General Hospital | Marion | Ohio | United States | 43302 |
359 | Toledo Clinic Cancer Centers-Maumee | Maumee | Ohio | United States | 43537 |
360 | Toledo Radiation Oncology at Northwest Ohio Onocolgy Center | Maumee | Ohio | United States | 43537 |
361 | UH Seidman Cancer Center at Lake Health Mentor Campus | Mentor | Ohio | United States | 44060 |
362 | UH Seidman Cancer Center at Southwest General Hospital | Middleburg Heights | Ohio | United States | 44130 |
363 | Licking Memorial Hospital | Newark | Ohio | United States | 43055 |
364 | University Hospitals Parma Medical Center | Parma | Ohio | United States | 44129 |
365 | Mercy Health Perrysburg Cancer Center | Perrysburg | Ohio | United States | 43551 |
366 | Southern Ohio Medical Center | Portsmouth | Ohio | United States | 45662 |
367 | Mercy Health - Saint Anne Hospital | Toledo | Ohio | United States | 43623 |
368 | Toledo Clinic Cancer Centers-Toledo | Toledo | Ohio | United States | 43623 |
369 | University Hospitals Sharon Health Center | Wadsworth | Ohio | United States | 44281 |
370 | UH Seidman Cancer Center at Saint John Medical Center | Westlake | Ohio | United States | 44145 |
371 | Genesis Healthcare System Cancer Care Center | Zanesville | Ohio | United States | 43701 |
372 | University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | United States | 73104 |
373 | Oklahoma Cancer Specialists and Research Institute-Tulsa | Tulsa | Oklahoma | United States | 74146 |
374 | Saint Alphonsus Medical Center-Baker City | Baker City | Oregon | United States | 97814 |
375 | Providence Cancer Institute Clackamas Clinic | Clackamas | Oregon | United States | 97015 |
376 | Legacy Mount Hood Medical Center | Gresham | Oregon | United States | 97030 |
377 | Providence Newberg Medical Center | Newberg | Oregon | United States | 97132 |
378 | Saint Alphonsus Medical Center-Ontario | Ontario | Oregon | United States | 97914 |
379 | Legacy Good Samaritan Hospital and Medical Center | Portland | Oregon | United States | 97210 |
380 | Providence Portland Medical Center | Portland | Oregon | United States | 97213 |
381 | Providence Saint Vincent Medical Center | Portland | Oregon | United States | 97225 |
382 | Legacy Meridian Park Hospital | Tualatin | Oregon | United States | 97062 |
383 | Lehigh Valley Hospital-Cedar Crest | Allentown | Pennsylvania | United States | 18103 |
384 | Lehigh Valley Hospital - Muhlenberg | Bethlehem | Pennsylvania | United States | 18017 |
385 | Pocono Medical Center | East Stroudsburg | Pennsylvania | United States | 18301 |
386 | Saint Vincent Hospital | Erie | Pennsylvania | United States | 16544 |
387 | Lehigh Valley Hospital-Hazleton | Hazleton | Pennsylvania | United States | 18201 |
388 | Jefferson Hospital | Jefferson Hills | Pennsylvania | United States | 15025 |
389 | Forbes Hospital | Monroeville | Pennsylvania | United States | 15146 |
390 | Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | United States | 19107 |
391 | Fox Chase Cancer Center | Philadelphia | Pennsylvania | United States | 19111 |
392 | Temple University Hospital | Philadelphia | Pennsylvania | United States | 19140 |
393 | Allegheny General Hospital | Pittsburgh | Pennsylvania | United States | 15212 |
394 | West Penn Hospital | Pittsburgh | Pennsylvania | United States | 15224 |
395 | Wexford Health and Wellness Pavilion | Wexford | Pennsylvania | United States | 15090 |
396 | Prisma Health Cancer Institute - Spartanburg | Boiling Springs | South Carolina | United States | 29316 |
397 | Prisma Health Cancer Institute - Easley | Easley | South Carolina | United States | 29640 |
398 | Prisma Health Cancer Institute - Butternut | Greenville | South Carolina | United States | 29605 |
399 | Prisma Health Cancer Institute - Faris | Greenville | South Carolina | United States | 29605 |
400 | Prisma Health Cancer Institute - Eastside | Greenville | South Carolina | United States | 29615 |
401 | Prisma Health Cancer Institute - Greer | Greer | South Carolina | United States | 29650 |
402 | Prisma Health Cancer Institute - Seneca | Seneca | South Carolina | United States | 29672 |
403 | Sanford Cancer Center Oncology Clinic | Sioux Falls | South Dakota | United States | 57104 |
404 | Sanford USD Medical Center - Sioux Falls | Sioux Falls | South Dakota | United States | 57117-5134 |
405 | Farmington Health Center | Farmington | Utah | United States | 84025 |
406 | University of Utah Sugarhouse Health Center | Salt Lake City | Utah | United States | 84106 |
407 | Huntsman Cancer Institute/University of Utah | Salt Lake City | Utah | United States | 84112 |
408 | Virginia Mason Medical Center | Seattle | Washington | United States | 98101 |
409 | Legacy Salmon Creek Hospital | Vancouver | Washington | United States | 98686 |
410 | Edwards Comprehensive Cancer Center | Huntington | West Virginia | United States | 25701 |
411 | West Virginia University Healthcare | Morgantown | West Virginia | United States | 26506 |
412 | Duluth Clinic Ashland | Ashland | Wisconsin | United States | 54806 |
413 | Marshfield Medical Center-EC Cancer Center | Eau Claire | Wisconsin | United States | 54701 |
414 | University of Wisconsin Carbone Cancer Center | Madison | Wisconsin | United States | 53792 |
415 | Marshfield Medical Center-Marshfield | Marshfield | Wisconsin | United States | 54449 |
416 | Marshfield Clinic-Minocqua Center | Minocqua | Wisconsin | United States | 54548 |
417 | ProHealth D N Greenwald Center | Mukwonago | Wisconsin | United States | 53149 |
418 | Cancer Center of Western Wisconsin | New Richmond | Wisconsin | United States | 54017 |
419 | ProHealth Oconomowoc Memorial Hospital | Oconomowoc | Wisconsin | United States | 53066 |
420 | Marshfield Medical Center-Rice Lake | Rice Lake | Wisconsin | United States | 54868 |
421 | Marshfield Medical Center-River Region at Stevens Point | Stevens Point | Wisconsin | United States | 54482 |
422 | ProHealth Waukesha Memorial Hospital | Waukesha | Wisconsin | United States | 53188 |
423 | UW Cancer Center at ProHealth Care | Waukesha | Wisconsin | United States | 53188 |
424 | Marshfield Medical Center - Weston | Weston | Wisconsin | United States | 54476 |
425 | Billings Clinic-Cody | Cody | Wyoming | United States | 82414 |
426 | Welch Cancer Center | Sheridan | Wyoming | United States | 82801 |
Sponsors and Collaborators
- National Cancer Institute (NCI)
Investigators
- Principal Investigator: Jennifer A Chan, Alliance for Clinical Trials in Oncology
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- NCI-2017-02297
- NCI-2017-02297
- A021602
- A021602
- U10CA180821