BEAM: Binge Eating Anxiety and Mood
Study Details
Study Description
Brief Summary
Binge Eating Disorder (BED) is the most common eating disorder, and currently, the best behavioral treatments only work for 40-60% of adults. BED often co-occurs with mood and anxiety disorders, and both are associated with neurocognitive deficits related to executive function (EF). These EF deficits contribute to worsening BED symptoms and make it difficult for these adults to adhere to treatment recommendations. The proposed study aims to develop an EF training enhanced behavioral treatment for BED and compare its effectiveness to the standard cognitive behavioral therapy for patients with BED and a co-occurring mood or anxiety disorder.
Condition or Disease | Intervention/Treatment | Phase |
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N/A |
Detailed Description
A randomized controlled trial (RCT) will evaluate an EF training enhanced cognitive behavioral therapy (CBT) for BED (EF-BED+CBT) compared to standard CBT in patients with BED and a comorbid mood/anxiety disorder to assess the feasibility, acceptability, and preliminary efficacy of EF-BED+CBT in reducing binge eating, impairment, and comorbid depression/anxiety symptoms. Adult participants with BED and comorbid mood/anxiety disorder will be randomized to a four month remote treatment of either EF-BED+CBT or CBT alone. Participants will be assessed at baseline, following treatment (month 4) and 2-month follow-up (month 6).
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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Experimental: Executive Function- Enhanced CBT for BED (EF-BED+CBT) EF-BED+CBT will combine CBT with executive function training, enhancing CBT with a focus on teaching compensatory strategies, habit learning, and plan for generalization to real-world behaviors. |
Behavioral: Executive Function- Enhanced CBT for BED (EF-BED+CBT)
EF-BED+CBT will combine CBT (see description below) with executive function training. EF-BED will focus on teaching compensatory strategies to enhance adherence to the strategies recommended in CBT.
Behavioral: Cognitive Behavioral Therapy (CBT)
CBT will be based on the "Overcoming Binge Eating" book. All participants will be provided a copy of the book. CBT addresses disturbed eating patterns and problematic thoughts/beliefs related to eating, shape and weight that contribute to binge eating. CBT is the current gold standard treatment for BED.
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Active Comparator: Cognitive Behavioral Therapy (CBT) CBT will be based on the "Overcoming Binge Eating" book. CBT addresses disturbed eating patterns and problematic thoughts/beliefs related to eating, shape and weight that contribute to binge eating. CBT is the current gold standard treatment for BED. |
Behavioral: Cognitive Behavioral Therapy (CBT)
CBT will be based on the "Overcoming Binge Eating" book. All participants will be provided a copy of the book. CBT addresses disturbed eating patterns and problematic thoughts/beliefs related to eating, shape and weight that contribute to binge eating. CBT is the current gold standard treatment for BED.
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Outcome Measures
Primary Outcome Measures
- Feasibility as measured by number of treatment sessions attended [Over the course of 4 months of treatment]
Attendance at Treatment Sessions
- Acceptability [At 4 months]
Ratings of usefulness of treatment measured by responses to Likert-type ratings developed by the study team.
Secondary Outcome Measures
- Binge Eating [Through study completion, an average of 6 months]
Change in binge eating episodes measured by the Eating Disorder Examination interview
- Impairment [Through study completion, an average of 6 months]
Change in impairment measured by the Clinical Impairment Assessment (CIA). The CIA is a 16-item questionnaire with possible scores ranging from 0-48 with a higher score indicating a greater level of impairment.
Other Outcome Measures
- Anxiety Symptoms [Through study completion, an average of 6 months]
Change in anxiety symptoms measured by the General Anxiety Disorder-7 (GAD-7). The GAD-7 is a 7-item questionnaire with scores ranging from 0-21 and a higher score indicating greater anxiety severity.
- Depression Symptoms [Through study completion, an average of 6 months]
Change in depression symptoms measured by the Patient Health Questionnaire-9 (PHQ-9). The PHQ-9 is a 9-item questionnaire with scores ranging from 0-27 and a higher score indicating greater depression severity.
Eligibility Criteria
Criteria
Inclusion Criteria:
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Age 18-65
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Ability to read English at a 6th grade level
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Clinical or subclinical BED and at least one comorbid mood or anxiety disorder
Exclusion Criteria:
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Known cognitive disability (e.g., brain injury with loss of consciousness >30 min, intellectual disability)
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Psychosis
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Psychiatric condition that could interfere with program participation (e.g., substance abuse, suicide attempt within previous 6 months, active purging, active suicidality)
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Currently pregnant, lactating or plan to be in the timespan of program follow-up
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Change in psychotropic medication or other medication that could have impact on weight, binge eating or anxiety/mood symptoms during the previous 3 months
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Participating in an organized program for overeating
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Ucsd Chear | San Diego | California | United States | 92037 |
Sponsors and Collaborators
- University of California, San Diego
- Brain & Behavior Research Foundation
Investigators
- Principal Investigator: Dawn M Eichen, PhD, UC San Diego
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- NARSAD YI 27943