BLAInostic: Bladder Cancer Detection Using Convolutional Neural Networks

Sponsor
Zealand University Hospital (Other)
Overall Status
Recruiting
CT.gov ID
NCT05193656
Collaborator
(none)
5,000
1
60
83.3

Study Details

Study Description

Brief Summary

The investigators aim to experiment and implement various deep learning architectures to achieve human-level accuracy in Computer-aided diagnosis (CAD) systems. In particular, the investigators are interested in detecting bladder tumors from CT urography scans and cystoscopies of the bladder in this project.

Condition or Disease Intervention/Treatment Phase
  • Diagnostic Test: Al_bladder

Detailed Description

The investigators aim to experiment and implement various deep learning architectures to achieve human-level accuracy in Computer-aided diagnosis (CAD) systems. In particular, the investigators are interested in detecting bladder tumors from CT urography scans and cystoscopies of the bladder in this project. The investigators want to classify bladder tumors as cancer, non cancer, high grade and low grade, invasive and non-invasive, with high sensitivity and low false positive rate using various convolutional neural networks (CNN). This task can be considered as the first step in building CAD systems for bladder cancer diagnosis. Moreover, by automating this task, the investigator scan significantly reduce the time for the radiologists to create large-scale labeled datasets of CT-urography scans and reduce the false-negative and positive that can happen due to human evaluation cystoscopies.

Study Design

Study Type:
Observational
Anticipated Enrollment :
5000 participants
Observational Model:
Cohort
Time Perspective:
Prospective
Official Title:
Bladder Cancer Detection Using Convolutional Neural Networks
Actual Study Start Date :
Jun 1, 2021
Anticipated Primary Completion Date :
Jun 1, 2026
Anticipated Study Completion Date :
Jun 1, 2026

Arms and Interventions

Arm Intervention/Treatment
Detecting bladder tumor

Patients with hematuria, or previous bladder tumor

Diagnostic Test: Al_bladder
Detection of bladder tumor with help of Artificial intelligence

Outcome Measures

Primary Outcome Measures

  1. Comparing standard technique to Machine Learning [5 years]

    The accuracy of Machine learning to detect bladder cancer compared to standard cystoscopy

Secondary Outcome Measures

  1. Detecting accuracy of subtypes of bladder cancer [5 years]

    The abelity of Machine Learning to identify high grad bladder cancer from low grad bladder cancer

Eligibility Criteria

Criteria

Ages Eligible for Study:
N/A and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • Patients with first time hematuria

  • Patients with the control program for previous bladder cancer

Exclusion Criteria:
  • Patients with control cystoscope for noncancer suspected disease

Contacts and Locations

Locations

Site City State Country Postal Code
1 Zealand University Hospital Roskilde Denmark 4000

Sponsors and Collaborators

  • Zealand University Hospital

Investigators

  • Principal Investigator: Nessn Azawi, phd, Zealand University Hospital

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Zealand University Hospital
ClinicalTrials.gov Identifier:
NCT05193656
Other Study ID Numbers:
  • SJ-905
First Posted:
Jan 18, 2022
Last Update Posted:
Jan 18, 2022
Last Verified:
Jun 1, 2021
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Zealand University Hospital
Additional relevant MeSH terms:

Study Results

No Results Posted as of Jan 18, 2022