Blood Collection for Research Related to Certain Diseases Involving Blood Vessels
Study Details
Study Description
Brief Summary
The collection of human specimens from both patients and healthy volunteers is necessary for the development of laboratory assays to further basic and clinical research studies. This protocol defines the purposes for which specimens will be collected and establishes general conditions under which sample collection will be performed....
Condition or Disease | Intervention/Treatment | Phase |
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Detailed Description
The collection of human specimens from both patients and healthy volunteers is necessary for the development of laboratory assays to further basic and clinical research studies. This protocol defines the purposes for which specimens will be collected and establishes general conditions under which sample collection will be performed.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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Group1 Clinical Center Patients, Healthy Volunteers |
Outcome Measures
Primary Outcome Measures
- evaluating the role of nitric oxide, inflammatory mediators, and endothelial function in inflammatory diseases of the vasculature such as sickle cell disease, coronary artery disease, pulmonary vascular or advanced lung disease, malaria, and sep... []
Eligibility Criteria
Criteria
- INCLUSION CRITERIA:
Males or females of age 18 years and older can be included in the study.
EXCLUSION CRITERIA:
Individuals without sickle cell disease or other chronic anemias who wish to donate blood will be excluded if the hemoglobin is less than 10 g/dL for women or less than 12g/dL for men.
Individuals with sickle cell disease or other chronic anemias will be excluded from donating blood samples if the hemoglobin is less than 6 g/dL.
A participant s most recent CBC result, obtained in the past 12 months, will be used to determine eligibility.
There are no exclusion criteria for participants donating saliva or urine.
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | National Institutes of Health Clinical Center | Bethesda | Maryland | United States | 20892 |
Sponsors and Collaborators
- National Heart, Lung, and Blood Institute (NHLBI)
Investigators
- Principal Investigator: Arun S Shet, M.D., National Heart, Lung, and Blood Institute (NHLBI)
Study Documents (Full-Text)
None provided.More Information
Additional Information:
Publications
None provided.- 030015
- 03-H-0015