capsular: Capsular Outcomes of Pediatric Cataract Surgery With Primary Intraocular Lens Implantation
Study Details
Study Description
Brief Summary
Lens capsular often changes after pediatric cataract surgery,causing complications such as anterior capsulerhexis shrinkage, visual axis opacification (VAO), zonular dehiscence and so on. The aim of study was to prospectively investigate the capsular outcomes of pediatric cataract surgery with primary intraocular lens (IOL) implantation.
Condition or Disease | Intervention/Treatment | Phase |
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Detailed Description
To investigate the capsular outcomes from a case series of children who underwent cataract surgery and primary IOL implantation at the Eye Hospital of Wenzhou Medical University between 2016 and 2019. Took Digital retro-illumination photographs of pediatric eyes at baseline and 6 months, 12 months, and the last visit postoperatively. Compare the capsular outcomes of the posterior capsule opening (PCO) area and visual axis transparent area at those time points, and analysis the correlations between the PCO area and influential factors, such as age at surgery, axial growth, and follow-up duration.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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pediatric cataract group Children who underwent cataract surgery and primary IOL implantation at the Eye Hospital of Wenzhou Medical University (Hangzhou, China) between 2016 and 2019 were included in the study. Every surgery included posterior capsulorhexis or capsulotomy and anterior vitrectomy. Patients accept slit-lamp-adapted anterior segmental photography at 1 week, 2 weeks, 1 month, 3 months, and 6 months postoperatively. |
Outcome Measures
Primary Outcome Measures
- PCOA [20.74 ± 7.89 months]
A comparison of posterior capsular opening areas at the corresponding time points
- VATA [20.74 ± 7.89 months]
A comparison of visual axis transparent areas at the corresponding time points
Secondary Outcome Measures
- axial length growth [20.74 ± 7.89 months]
The growth of axial length at the corresponding time points
Eligibility Criteria
Criteria
Inclusion Criteria:
Children (age 0.5~8 years) who underwent cataract surgery, posterior capsulorhexis or capsulotomy and anterior vitrectomyand primary IOL implantation at the Eye Hospital of Wenzhou Medical University (Hangzhou, China). The follow-up period was at least 1 year.
Exclusion Criteria:
Patients with ocular trauma, corneal disorders, glaucoma, preoperative lens luxation or subluxation, membranous cataract, persistent hyperplastic primary vitreous, surgical or postoperative complications such as glaucoma or suspect-glaucoma and synechia, pupils that could not be sufficiently dilated, and those who could not complete follow-ups or did not have clear digital photographs.
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Ophthalmology and Optometry Hospital | Wenzhou | Zhejiang | China | 325027 |
Sponsors and Collaborators
- Yune Zhao
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
- Lin H, Tan X, Lin Z, Chen J, Luo L, Wu X, Long E, Chen W, Liu Y. Capsular Outcomes Differ with Capsulorhexis Sizes after Pediatric Cataract Surgery: A Randomized Controlled Trial. Sci Rep. 2015 Nov 5;5:16227. doi: 10.1038/srep16227.
- Tan X, Lin H, Lin Z, Chen J, Tang X, Luo L, Chen W, Liu Y. Capsular Outcomes After Pediatric Cataract Surgery Without Intraocular Lens Implantation: Qualitative Classification and Quantitative Measurement. Medicine (Baltimore). 2016 Mar;95(10):e2993. doi: 10.1097/MD.0000000000002993.
- cataract- fuyana