Is Carotid-Vertebral Doppler Ultrasonography Necessary for Patients With Vertigo?

Sponsor
Pamukkale University (Other)
Overall Status
Recruiting
CT.gov ID
NCT05196685
Collaborator
(none)
100
1
18.9
5.3

Study Details

Study Description

Brief Summary

This study will be carried out prospectively on patients who applied to the cardiovascular surgery polyclinic and the carotid-vertebral artery doppler ultrasound due to the vascular problem. All patients will fill "Balance Disorder Scan Survey" and "Vertigo-Dizziness Imbalance Questionnaire-SS". Patients who score 1 and more are directed to the ear nose throat polyclinic and detailed differential diagnosis. Those who score 0 will be in control group.

Condition or Disease Intervention/Treatment Phase
  • Diagnostic Test: Carotid Doppler USG

Detailed Description

Right and left carotid artery flow velocities, intima-media thicknesses (IMT), presence of plaque, vertebral artery flow velocities, and vertebral artery resistance indexes (RI) will be recorded in all patients. Risk factor analysis, Vertigo Symptom Scale (VSS) and Dizziness Handicap Inventory (DHI-S) questionnaires will be applied to the patients in the ENT outpatient clinic. The differential diagnosis of vertigo will be made by performing detailed balance examinations and advanced balance tests.

Study Design

Study Type:
Observational
Anticipated Enrollment :
100 participants
Observational Model:
Case-Control
Time Perspective:
Cross-Sectional
Official Title:
Is Carotid-Vertebral Doppler Ultrasonography Necessary for Patients With Vertigo?
Actual Study Start Date :
Feb 1, 2021
Anticipated Primary Completion Date :
Aug 1, 2022
Anticipated Study Completion Date :
Aug 31, 2022

Arms and Interventions

Arm Intervention/Treatment
Group Vertigo

Patients who have Carotid Doppler Ultrasonography and Vertigo screening test scores of 1 and above will be sent to ENT

Diagnostic Test: Carotid Doppler USG
All Doppler ultrasonography measurements will be made in a dimly lit room at room temperature, with the patient in the supine position, the head slightly hyperextended, the patient looking to the left when measuring the right side, and the patient looking to the right when measuring the left side. In all patients, common carotid artery (CCA), internal carotid artery (ICA) and vertebral artery (VA) gray scale and color Doppler ultrasonography wşll be performed using the GE 9L Linear Probe. Color Doppler examination will be performed with a frequency of 4.0/8.0 MHz.

Group control

Patients who have Carotid Doppler Ultrasonography and Vertigo screening test score below 1

Diagnostic Test: Carotid Doppler USG
All Doppler ultrasonography measurements will be made in a dimly lit room at room temperature, with the patient in the supine position, the head slightly hyperextended, the patient looking to the left when measuring the right side, and the patient looking to the right when measuring the left side. In all patients, common carotid artery (CCA), internal carotid artery (ICA) and vertebral artery (VA) gray scale and color Doppler ultrasonography wşll be performed using the GE 9L Linear Probe. Color Doppler examination will be performed with a frequency of 4.0/8.0 MHz.

Outcome Measures

Primary Outcome Measures

  1. Carotid Stenosis [1 year]

    ECST for Carotid Stenosis measurement will be used. In the ECST the estimated normal lumen diameter at the site of the lesion, based on a visual impression of where the normal arterial wall is before development of the stenosis, is used.

  2. Resistive Index [1 year]

    Measurements are taken from vertebral artery and formulated as below. Resistive Index = peak systolic velocity - end diastolic velocity] / peak systolic velocity

  3. Intima Media Thickness [1 year]

    The intima-media thickness will be measured 1 cm proximal to the start of the carotid bulb dilatation on the CCA in the far wall. Using the cine-loop function, an optimal longitudinal freeze-frame image in the end-diastolic state is measured manually.

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • All patients who have a vascular problem and doppler USG.
Exclusion Criteria:

Patients with impaired cooperation, history of malignancy, presence of central nervous system pathology, presence of neurological disease affecting balance in the history, patients whose use of glasses may cause problems (epilepsy, vision loss, etc.) were excluded from the study.

Contacts and Locations

Locations

Site City State Country Postal Code
1 Pamukkale University Denizli Turkey 20070

Sponsors and Collaborators

  • Pamukkale University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Fazıl Necdet Ardıç, Prof. Dr., Pamukkale University
ClinicalTrials.gov Identifier:
NCT05196685
Other Study ID Numbers:
  • 10
First Posted:
Jan 19, 2022
Last Update Posted:
Jun 14, 2022
Last Verified:
Jun 1, 2022
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Fazıl Necdet Ardıç, Prof. Dr., Pamukkale University
Additional relevant MeSH terms:

Study Results

No Results Posted as of Jun 14, 2022