Lidocaine Usage for Pupil Dilatation (Mydriasis)
Study Details
Study Description
Brief Summary
The purpose of this study is to determine if the mydriatic effect of intracameral lidocaine 1% is as effective as topical cyclopentolate 1% and phenylephrine 10% for achieving effective mydriasis during phacoemulsification surgery.
Condition or Disease | Intervention/Treatment | Phase |
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N/A |
Detailed Description
Former studied done on the effect of Intracameral lidocaine 1% compared to topical mydriatic agents for achieving effective mydriasis during phacoemulsification surgery have compared 2 different groups of patients, ie; One group received topical agents and the other received intracameral lidocaine. The resultant pupil size was recorded and evaluated in the 2 groups. Our purpose is to compare the effect of these agents on the same group of people.
Patients recruited will be invited first for evaluation at least 1 week before the surgery. During this evaluation 1 dose (drop) of topical cyclopentolate 1% and Phenylephrine 10% will be instilled to the evaluated eye 3 times at 10 minutes intervals. After 1 hour from the last instillation pupil diameter will be recorded. In the second part of this study during the phacoemulsification surgery patients will be given intracamerally lidocaine 1% (0.2 ml) and the pupil size will be recorded after 90 seconds. the resultant values will be evaluated/compared.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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Experimental: Lidmyd The same group is used for the first and the second part of the experiment. Initially the patients will be given topical cyclopentolate 1% and Phenylephrine 10% and the pupil diameter will be recorded. In the second part of the experiment lidocaine 1% will be introduced intracamerally and the pupil size will be recorded again. The 2 measurements will be statistically compared/evaluated. |
Drug: Lidocaine 1% (sterile)
during the phacoemulsification surgery patients will be given intracamerally lidocaine 1% (0.2 ml) and the pupil size will be recorded after 90 seconds
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Outcome Measures
Primary Outcome Measures
- Pupil size after mydriatics [no longer then 1 year]
We would like to evaluate whether Pupil size dilated with Intracameral Lidocaine 1% is as effective dilator compared with Topical Cyclopentolate 1% and Phenylephrine 10%
Eligibility Criteria
Criteria
Inclusion Criteria:
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cataract
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men and women
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can read and sign informed consent form
Exclusion Criteria:
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sensitivity to Lidocaine
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sensitivity to Ephrine
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any other ocular surgeries
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diseases like Adie's pupil, Horner syndrome
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Carmel Medical Center
Investigators
- Principal Investigator: Orna Geyer, Professor, Carmel Medical Center
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- CMC-09-0017-CTIL