Cervical Cancer Screening Strategies
Study Details
Study Description
Brief Summary
This study is to investigate retrospectively the results of cervical cytology and high-risk human papillomavirus in the past 20 years recorded in Peking Union Medical College Hospital. The histological findings after cervical cancer screening were reviewed. The diagnostic values of different screening strategies were compared based on the results of cervical histology. The primary endpoint is the diagnosis of grade 2 cervical intraepithelial neoplasia (CIN2) or more severe lesions (CIN2+). The secondary endpoints include following objectives: (1) the invasive procedures needed according to the screening results; (2) the diagnosis of vaginal and/or vulval intraepithelial neoplasia; (3) the persistence and recurrence of human papillomavirus infection; and (4) the cost-effectiveness of screening strategies for CIN2+.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
Study Design
Outcome Measures
Primary Outcome Measures
- CIN2+ [One year]
CIN2+ detected by various screening methods
Secondary Outcome Measures
- Invasive procedures [One year]
Invasive procedures needed according to the screening results
- Vaginal intraepithelial neoplasia (VaIN) [One year]
VaIN detected by various screening methods
- Vulval intraepithelial neoplasia (VIN) [One year]
VIN detected by various screening methods
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Aged 18 years or older
-
With definite cervical histology after cervical cancer screening, ore with at least one screening test after first testing
Exclusion Criteria:
- Not meeting all of the inclusion criteria
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | Lei Li | Beijing | Beijing | China | 100730 |
Sponsors and Collaborators
- Lei Li
Investigators
- Principal Investigator: Lei Li, M.D., Peking Union Medical College Hospital
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- EVUCC