China biobank: China Health Big Data

Sponsor
Beijing Jishuitan Hospital (Other)
Overall Status
Recruiting
CT.gov ID
NCT03699228
Collaborator
Chinese PLA General Hospital (Other), Ruijin Hospital (Other), Huashan Hospital (Other), Henan Provincial People's Hospital (Other), The Affiliated Hospital Of Guizhou Medical University (Other), Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (Other), The First Affiliated Hospital of Zhengzhou University (Other), First Affiliated Hospital Xi'an Jiaotong University (Other), The renmin hospital of wuhan university (Other), Nanjing BenQ Hospital (Other), China-Japan Friendship Hospital (Other), xinan hospital (Other), Wu Hu Yijishan hospital (Other), The fifth affiliated hospital of zhong shan university (Other)
30,000
Enrollment
6
Locations
61
Anticipated Duration (Months)
5000
Patients Per Site
82
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

In this nationwide multi center study the investigators combine the low dose chest CT scan data with QCT technology, to measure the BMD of spine, VAT and liver fat in the health check subjects. The aim of this study is to evaluate the performance of QCT in the health check field, and further to evaluate the prevalence of osteoporosis, obesity and liver steatosis in health check population across China.

Condition or DiseaseIntervention/TreatmentPhase

    Detailed Description

    Low dose Chest CT scan is the standard for lung cancer in the health check center in China. Quantitative computed tomography (QCT) is utilizing the CT raw data to measure the bone mineral density (BMD), the visceral fat (VAT) and liver fat content in human, which can be widely used in the diagnosis of osteoporosis, the assessment of obesity and liver steatosis. In this nationwide multi center study the investigators combine the low dose chest CT scan data with QCT technology, to measure the BMD of spine, VAT and liver fat in the health check subjects. This study is to evaluate the performance of QCT in the health check field, and further to evaluate the prevalence of osteoporosis, obesity and liver steatosis in health check population across China.

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    30000 participants
    Observational Model:
    Other
    Time Perspective:
    Prospective
    Official Title:
    China Nationwide Multi Center Big Data Study on the Quantitative Computed Tomography (QCT) and Health Status of Check -up Population
    Actual Study Start Date :
    Dec 1, 2017
    Anticipated Primary Completion Date :
    Jun 30, 2022
    Anticipated Study Completion Date :
    Dec 31, 2022

    Outcome Measures

    Primary Outcome Measures

    1. The spinal volumetric bone mineral density (vBMD) [2 year]

      The volumetric bone mineral density of L1-2 measured by QCT

    Secondary Outcome Measures

    1. The visceral adipose tissue (VAT) [2 year]

      The visceral adipose tissue (VAT) measured by quantitative computed tomography (QCT)

    2. Liver fat [2 years]

      Liver fat measurement by quantitative computed tomography (QCT)

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    30 Years to 90 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:

    health check subjects 30-90 years old low dose chest CT scan

    Exclusion Criteria:

    pregnant women metal implant in the CT scan area

    Contacts and Locations

    Locations

    SiteCityStateCountryPostal Code
    1Wu Hu Yijishan HospitalWu HuAnhuiChina100035
    2Beijing Jishuitan hospitalBeijingBeijingChina100035
    3The first affiliated hospital of Guiyang Medical UniversityGuiyangGuizhouChina
    4The first affiliated hospital of Zhengzhou UniversityZhengzhouHenanChina
    5Hua Shan hospitalShanghaiShanghaiChina
    6Shanghai Ruijin hospitalShanghaiShanghaiChina

    Sponsors and Collaborators

    • Beijing Jishuitan Hospital
    • Chinese PLA General Hospital
    • Ruijin Hospital
    • Huashan Hospital
    • Henan Provincial People's Hospital
    • The Affiliated Hospital Of Guizhou Medical University
    • Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
    • The First Affiliated Hospital of Zhengzhou University
    • First Affiliated Hospital Xi'an Jiaotong University
    • The renmin hospital of wuhan university
    • Nanjing BenQ Hospital
    • China-Japan Friendship Hospital
    • xinan hospital
    • Wu Hu Yijishan hospital
    • The fifth affiliated hospital of zhong shan university

    Investigators

    • Principal Investigator: xiaoguang cheng, MD, Beijing Jishuitan Hospital
    • Principal Investigator: qiang zeng, General PLA hospital

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    xiaoguang Cheng, professor of radiology, chairman of department, Beijing Jishuitan Hospital
    ClinicalTrials.gov Identifier:
    NCT03699228
    Other Study ID Numbers:
    • jst2018
    First Posted:
    Oct 9, 2018
    Last Update Posted:
    Nov 18, 2021
    Last Verified:
    Nov 1, 2021
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by xiaoguang Cheng, professor of radiology, chairman of department, Beijing Jishuitan Hospital
    Additional relevant MeSH terms:

    Study Results

    No Results Posted as of Nov 18, 2021