Distress and Immunotherapy
Study Details
Study Description
Brief Summary
The study includes participants experiencing distress with regard to stopping immunotherapy and will utilize cognitive-behavioral therapy to reduce fear of recurrence, depression, and anxiety and improve quality of life.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
N/A |
Detailed Description
The intervention will be delivered through telemedicine to reduce the patient-related barriers to treatment including cost, transportation, and being able to maintain appointments while managing the side effects of treatment. The intervention will provide the patient with skills to reduce distress associated with ceasing treatment of a checkpoint inhibitor through the development evidence-based psychological and behavioral strategies that are tailored to the patients' preferences.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Experimental: Cessation of treatment
|
Behavioral: cognitive behavioral therapy
Cognitive-behavioral therapy involves changing these erroneous cognitions and beliefs through cognitive restructuring, modification of behavior, and development of alternative coping skills.
|
Outcome Measures
Primary Outcome Measures
- Reduce fear of recurrence [3 months]
Change by 50%
Secondary Outcome Measures
- Improve quality of life [3 months]
Change of quality of life by 5 points
- Reduction of anxiety [3 months]
Change of anxiety by 2 points
- Depressive symptoms [3 months]
Change by 25%
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Age 21 years and older
-
Fluent in English
-
Diagnosis of cancer and history of treatment with immunotherapy
Exclusion Criteria:
- Active suicidal ideation, delusions or hallucinations
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | UPMC Hillman Cancer Centers | Pittsburgh | Pennsylvania | United States | 15213 |
Sponsors and Collaborators
- University of Pittsburgh
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- STUDY19110214