EAST-west Colorectal Study
Study Details
Study Description
Brief Summary
Colorectal resection due to benign and malignant diseases is a commonly performed procedure. The continuity of the gastrointestinal tract is re-established by creating an anastomosis. Although such procedures are often performed, anastomotic techniques and postoperative outcomes usually vary. Failure of the anastomosis might be a life-threatening condition after colorectal resection. A relatively high incidence of anastomotic leaks (up to 30%) has been reported worldwide. Anastomotic failure could happen due to several reasons, that are divided into surgeon-related factors and patient-related factors. So far, there has been no data about the incidence of anastomotic leak in the Western Balkans and the Mediterranean countries.The aim of EAST-WEST Colorectal Study 2022 is to investigate differences in patients undergoing colorectal resections, including pre-operative patient preparation, history of prior surgeries and anastomotic techniques. In addition, this study aims to collect data about post-operative complication rate within 30 days post-surgery across Balkan countries (Greece, Romania and Malta). This would enable variabilities in practice to be identified and differences regarding postoperative outcomes to be highlighted.
Condition or Disease | Intervention/Treatment | Phase |
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Study Design
Outcome Measures
Primary Outcome Measures
- Leakage rate [30 days]
Secondary Outcome Measures
- Re-admission rate within the first 30 days post-surgery. [30 days]
- 30-day postoperative morbidity [30 days]
- 30-day postoperative mortality [30 days]
- Clavien-Dindo complication classification [30 days]
- Length of stay [30 days]
Eligibility Criteria
Criteria
Inclusion Criteria:
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Adults between 18-90 years old undergoing colorectal resection with anastomosis due to benign and malignant diseases
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Any of the procedures listed below performed as an emergency or elective surgery, and by any approach; open, laparoscopic or robotic:
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Right hemicolectomy and extended right hemicolectomy
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Ileocecal resection
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Transverse colon resection
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Segmental colonic resection - i.e. splenic resection
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Left hemicolectomy
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Sigmoid resection
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Rectal resection
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Pan-proctocolectomy
Exclusion Criteria:
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Closure of ileostomy or colostomy
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Creation of multiple anastomoses
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Small bowel resection
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Pelvic exenteration
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Cytoreductive surgery
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- National and Kapodistrian University of Athens
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- EAST-west 2022