Pulmonary Tuberculosis Sequelae in Patients With COPD
Study Details
Study Description
Brief Summary
It is known that there is a complex relationship between tuberculosis and COPD. Post-tuberculosis airway disease or COPD associated with tuberculosis occurs in a significant portion of tuberculosis patients. However, it was observed that mortality rates and exacerbation rates of COPD patients with tuberculosis sequel were higher. However, the effect of tuberculosis sequela on functional outcomes in COPD patients has not been investigated in the studies.
The aim of this study is to determine whether the previous tuberculosis sequelae has a functional effect on patients with COPD.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Detailed Description
This research is planned as a cross-sectional study. It will start within one week following the approval of the ethics committee and will be completed within one year. The universe of the study is S.B.Ü. Dr. Suat Seren Chest Diseases and Surgery Training and Research Hospital consists of patients who apply to Pulmonary Rehabilitation Outpatient Clinic. Participants will consist of two different groups: COPD patients with tuberculosis and COPD patients without tuberculosis. The voluntary principle will be taken into account in participating in the research.
Within the scope of the evaluation; Demographic and clinical information of the people who will participate in the study will be recorded, and Thorax CT and PFT examinations performed within the polyclinic service within the last 1 month will be evaluated. Saint George Respiratory Questionaire (SGRQ), 6-minute walk test (6MWT), Medical Research Council Dyspnea Scale (MRC), COPD assessment test (CAT) will be applied to the patients. Regarding the illness histories, the number of hospitalizations and emergency admissions in the last 1 year will be recorded. Detailed tuberculosis anamneses will also be taken from patients with tuberculosis sequelae.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| COPD patients with tuberculous sequelae COPD patients with tuberculous sequelae |
Other: Functional Outcome Measurements
Dyspnea Exercise capacity Quality of life assessment
|
| COPD patients without tuberculosis sequela COPD patients with tuberculous sequelae |
Other: Functional Outcome Measurements
Dyspnea Exercise capacity Quality of life assessment
|
Outcome Measures
Primary Outcome Measures
- Exercise Capacity [6 minutes- baseline]
Six minutes walk test
Secondary Outcome Measures
- Dyspnea Assessment [5 minutes- baseline]
Medical Research Council Scale(MRC)
- COPD Assessment [5 minutes- baseline]
COPD Assessment Test (CAT
- Quality of Life Assessment [20 minutes- baseline]
St. George Respiratory Questionaire
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Volunteering to participate in the study
-
Being over 18 years old
-
Having thorax CT in the last 1 month
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Having PFT examination performed in the last 1 month
Exclusion Criteria:
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Being in a COPD attack
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The patient has additional pulmonary comorbidity such as Lung Ca, bronchiectasis, lung fibrosis.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | İlknur Naz Gürşan | İzmir | Turkey | 35620 |
Sponsors and Collaborators
- Izmir Katip Celebi University
Investigators
- Principal Investigator: Hulya Sahin, Izmir Dr. Suat Seren Chest Diseases and Surgery Training and Research Hospital
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- IKC145