Efficacy of Xiidra in Dry Eye Disease After Collagen Cross Linking
Study Details
Study Description
Brief Summary
dry eye disease after corneal collagen cross linking affect ocular function leading to reduced vision, photophobia, glare, halos, and foreign body sensation.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
Phase 4 |
Detailed Description
first group of patients were treated with 0.5 % xiidra twice daily and artificial tears for 6 months.Second group treated with artificial tears for 6 months. the treatment starts after corneal collagen cross linking in both groups ,Baseline and post-treatment full ophthalmic examination was done.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Experimental: xiidra group patients are treated with 0.5 % xiidra twice daily and artificial tears for 6 months after corneal collagen cross linking |
Drug: Xiidra 5% Ophthalmic Solution
lifitegrast 0.5% ia applied twice daily after corneal collagen cross linking
Other Names:
|
No Intervention: control group patient are treated with artificial tears for 6 months after corneal collagen cross linking in both groups |
Outcome Measures
Primary Outcome Measures
- Change in Break up Time [6 months]
fluorescein sodium stripes will be used for measurement of Break up Time in seconds at baseline and during the study
Eligibility Criteria
Criteria
Inclusion Criteria:
- corneal collagen cross linking
Exclusion Criteria:
- systemic or ocular diseases ,previous ocular surgery, corneal pathology and contact lens wearers
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | INMC | Abu Dhabi | United Arab Emirates | 46266 |
Sponsors and Collaborators
- Benha University
Investigators
- Principal Investigator: Tarek Elhamaky, Benha university faculty of medicine
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- Hamaky17