CICM-SCP: CCTA Improves Clinical Management of Stable Chest Pain
Study Details
Study Description
Brief Summary
The investigator aims to prospectively enroll patients who were referred for coronary computed tomography angiography (CCTA) for the assessment of stable chest pain (SCP) suspected of obstructive coronary artery disease (CAD). All patients underwent CCTA according to established guidelines and local institutional protocols. The imaging data were evaluated using different image post-processing software to comprehensively analyse anatomical, functional and histological information of coronary. This study will determine if CCTA-based imaging evaluation can provide more informaton to improve clinical management for SCP, including fewer MACE and better decision-making of downstream investigations and therapeutic interventions.
Condition or Disease | Intervention/Treatment | Phase |
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Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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CCTA
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Diagnostic Test: CCTA
All patients underwent CCTA according to established guidelines and local institutional protocols. The imaging data were evaluated using different image post-processing software to comprehensively analyse anatomical, functional and histological information of coronary.
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Outcome Measures
Primary Outcome Measures
- Major adverse cardiovascular events [3 years]
Cardiac death and myocardial infarction
Secondary Outcome Measures
- Invasive coronary angiography [3 years]
Invasive coronary angiography occurred at follow-up after CCTA, attributed to CCTA results or unplanned.
- Medication prescription [3 years]
Change for medication prescription of antiplatelet agents, anti-ischemic drugs, lipid-lowering agents, angiotensin-converting enzyme inhibition and so on, attributed to CCTA results or unplanned,
- Coronary revascularization [3 years]
PTCA, PCI or CABG occurred at follow-up after CCTA, attributed to CCTA results or unplanned.
Eligibility Criteria
Criteria
Inclusion Criteria:
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symptomatic patients with SCP suspected of obstructive CAD.
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referred for CCTA for the assessment of SCP.
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≥18 years of age.
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signed informed consent.
Exclusion Criteria:
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acute coronary syndromes,
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previous CAD or coronary revascularization
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nonsinus rhythm
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cardiomyopathy, valvular disease, congenital heart disease or left cardiac insufficiency because of other reasons
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missing data
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Beijing Chaoyang Hospital | Beijing | China | ||
2 | Tianjin Chest Hospital | Tianjin | China | 300000 |
Sponsors and Collaborators
- Tianjin Chest Hospital
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- TJCHCCTA-01