Correlation Between Elastic Modulus of Ultrasonic Shear Wave and Tumor Stromal Component in Pancreatic Cancer
Study Details
Study Description
Brief Summary
Pancreatic cancer is a gastrointestinal tumor with a high degree of malignancy. Currently, there are many first-line chemotherapy regimens in clinical practice, but the individual selection of chemotherapy regimens has not been unanimously recognized.This study is aimed at exploring the correlation between the two-dimensional shear wave elastography (2D - SWE) parameters and pancreatic cancer stromal elements proportion through an ultrasound scan for resectable pancreatic cancer cases and postoperative pathological specimen analysis. Then determine if the pancreatic cancer two-dimensional shear wave elastography can guide clinicians selecting chemotherapy scheme by predicting tumor stromal elements .These results are expected to provide an effective non-invasive diagnostic basis for individualized treatment of pancreatic cancer.
Condition or Disease | Intervention/Treatment | Phase |
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Study Design
Outcome Measures
Primary Outcome Measures
- Elastic modulus measured by Ultrasonic shear wave and tumor stromal component assessed by pathological analysis in pancreatic cancer [Baseline (Preoperative ultrasound elastography examination)]
Eligibility Criteria
Criteria
Inclusion Criteria
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Patients with resectable pancreatic cancer underwent ultrasound examination before surgery
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Conventional ultrasound can clearly show pancreatic space-occupying lesions and the elastic measurements show good images
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The patient agrees to receive ultrasound elasticity examination and signs informed consent
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All patients had no history of radiotherapy or chemotherapy before ultrasound examination
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All clinical case data and auxiliary examination data are complete and accessible.
Exclusion Criteria
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Ultrasound evaluation was not performed before ultrasound-guided needle biopsy
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Conventional ultrasound could not clearly show pancreatic space-occupying lesions or poor elastic measurement images
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Patients who refuse to accept examination or give up treatment
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Patients receiving neoadjuvant chemotherapy or radiotherapy before ultrasound examination
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Incomplete clinical data and auxiliary examination data.
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Xijing Hospital | Xi'an | Shaanxi | China | 710032 |
Sponsors and Collaborators
- Xijing Hospital
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- KY20212175-C-1