D-Dimer as Predictor of Disease Outcome in Intensive Care Unit in COVID-19m Patients

Sponsor
Ain Shams University (Other)
Overall Status
Completed
CT.gov ID
NCT05279469
Collaborator
(none)
465
2
8.9
232.5
26

Study Details

Study Description

Brief Summary

Evaluating value of D-Dimer blood level of icu admitted patients on admission and 48 hours later as outcome predictor in SARS.COV.2 patients.

Condition or Disease Intervention/Treatment Phase
  • Other: no intervention, just observational for D-Dimer level in blood

Detailed Description

Evaluating value of D-Dimer blood level of icu admitted patients on admission and 48 hours later as outcome predictor in SARS.COV.2 patients.

It has been reported that COVID 19 is associated with hemostatic abnormalities and elevated D-Dimer level, so its level is used to predict severity of disease.

Study Design

Study Type:
Observational
Actual Enrollment :
465 participants
Observational Model:
Case-Only
Time Perspective:
Retrospective
Official Title:
D-Dimer as Predictor of Disease Outcome in Intensive Care Unit in SARS-COV-2 Patients: A Retrospective Study
Actual Study Start Date :
Jun 10, 2021
Actual Primary Completion Date :
Mar 3, 2022
Actual Study Completion Date :
Mar 9, 2022

Outcome Measures

Primary Outcome Measures

  1. 28 days mortality [1 month]

    Outcomes of ICU stay

Secondary Outcome Measures

  1. length of stay and mechanical ventilation [during ICU stay]

    time of admission and need to escalate oxygen therapy

Eligibility Criteria

Criteria

Ages Eligible for Study:
N/A and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • patients of both sex admitted in icu

  • positive PCR

  • requiring oxygen therapy

Exclusion Criteria:
  • ward patients

  • negative PCR

Contacts and Locations

Locations

Site City State Country Postal Code
1 Ain shams university hospitals Cairo Egypt
2 Faculty of medicine, Ain Shams University Cairo Egypt

Sponsors and Collaborators

  • Ain Shams University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Amr M Hilal Abdou, Assistant Professor, Ain Shams University
ClinicalTrials.gov Identifier:
NCT05279469
Other Study ID Numbers:
  • MS56/2022
First Posted:
Mar 15, 2022
Last Update Posted:
Mar 15, 2022
Last Verified:
Mar 1, 2022
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Amr M Hilal Abdou, Assistant Professor, Ain Shams University
Additional relevant MeSH terms:

Study Results

No Results Posted as of Mar 15, 2022