Data Collection of Standard Care and Evaluation of NHLBI Patients and Donors
Study Details
Study Description
Brief Summary
Background:
Researchers seek ways to study people s medical problems in order to teach and further general knowledge. The ability to assess and treat people with a wide range of diseases is critical to training people to be good doctors. It is also needed to keep medical staff up to date. In this study, researchers want to study the course of some illnesses to learn more about them. To do this, they will collect and review people s medical records. In some cases, they may also provide treatment.
Objective:
To collect data that may be used to help researchers create ideas for future research.
Eligibility:
People age 2 and older who have or are suspected to have a medical condition for which they have been referred to NIH s National Heart, Lung, and Blood Institute, as well as stem cell donors
Design:
Participants may be screened with a review of the following:
Medical records
Scans and images
Other existing samples and reports.
Participants medical data will be collected from the standard care they receive. This includes their routine blood and urine tests, X-rays and scans, and other tests to diagnose or follow their medical condition. Data will also be collected from the treatments they may receive. For stem cell donors, data from apheresis procedures will be collected. Demographic data will also be collected.
All of the data will be kept in the medical records or on secure network drives.
Some participants may need to be treated for their medical condition. If so, they will sign a separate consent form for that treatment.
Participation lasts up to 2 years.
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| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Detailed Description
This protocol is designed to provide a repository of information to allow for hypothesis generation in future research. This information will be drawn from standard medical care/procedures and follow up of patients and healthy volunteers, including transplant donors, who are not currently receiving therapy on an active NHLBI research protocol. It allows investigation into the problems of these patients for the purpose of teaching and furthering general knowledge. The ability to evaluate and treat patients with a wide variety of diseases is critical to maintaining our accreditation with the hematology-oncology, cardiology, and pulmonary fellowship programs and training our fellows to be competent physicians, as well as for keeping all staff, including senior staff, up-to-date and familiar with the evaluation and treatment of patients with a wide spectrum of diseases. Periodic follow-up and treatment of patients previously entered on NHLBI protocols in order to monitor the long-term course of the underlying disease and the consequences of experimental treatments is also required for fellowship training, and for maintenance of good referral relationships with patients and their physicians. This study also allows for standard apheresis procedures for transplant donors and for care of volunteers who may present with a treatable condition.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| 1 Data collection and treatment according to guidelines of standard of medical evaluation and care. No investigational treatments or procedures will be administered on this protocol. |
Outcome Measures
Primary Outcome Measures
- To provide a repository of information on enrolled participants to allow for hypothesis generation in future research [20 years]
To provide a repository of information on enrolled participants to allow for hypothesis generation in future research
Secondary Outcome Measures
- To add value to the NHLBI training program [20 years]
To add value to the NHLBI training program by providing consult, treatment, diagnostic tests, and medical follow-up of participants
Eligibility Criteria
Criteria
- ELIGIBILITY:
- Patients (including those referred to us to rule out a disease or condition) and stem cell donors,
may be entered on this protocol at the discretion of the Principal and/or Associate Investigators.
- The patient or the patient's Legally Authorized Representative is capable of informed consent and
signs the consent form. The consent form will be signed by parents or guardians of patients under
the age of 18.
- Age more than or equal to 2 and weight > 12 kg
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | National Institutes of Health Clinical Center | Bethesda | Maryland | United States | 20892 |
Sponsors and Collaborators
- National Heart, Lung, and Blood Institute (NHLBI)
Investigators
- Principal Investigator: Georg Aue, M.D., National Heart, Lung, and Blood Institute (NHLBI)
Study Documents (Full-Text)
None provided.More Information
Additional Information:
Publications
None provided.- 200099
- 20-H-0099