Assessment of Vital Pulp Therapy in Permanent Molars
Study Details
Study Description
Brief Summary
The purpose of this study is to evaluate the long term clinical performance of vital pulp therapy of young permanent teeth with irreversible pulpitis
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Detailed Description
Permanent molar teeth meeting the inclusion criteria will be included into the study. Following local anaesthesia and dental dam application, caries excavation will be performed; and after exposure, the pulp will be amputated to the level of the canal orifices (full pulpotomy) using a sterile high-speed round bur under water coolant. After haemostasis is achieved, Mineral trioxide aggregate (MTA) will be gently placed over the pulp to a thickness of 2-3 mm and the tooth will be restored using glass ionomer cement and composite resin. A postoperative periapical radiograph will be taken. Patients will be reviewed at 6., 12., 24. and 36. months for clinical and radiographical success. The data will be analysed statistically using chi square test.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: NeoMTA Vital pulp therapy with NeoMTA |
Device: NeoMTA
NeoMTA™ Plus® root and pulp treatment material is a powder/gel system with no resin. The components are an extremely fine powder primarily tricalcium and dicalcium silicate plus a water-based gel.
|
Outcome Measures
Primary Outcome Measures
- Clinical evaluation of vital pulp therapy in permanent teeth with irreversible pulpitis [3 years]
Long-term success of vital pulp therapy in young permanent teeth with irreversible pulpitis. Evaluation criteria will be; spontaneous pain (absent/present); tenderness to percussion/palpation (absent/present); mobility (no mobility/ 1mm/ 2mm/ 3mm mobility) swelling (absent/present); fistula (absent/present) periapical/interradicular radiolucency (absent/present); widened periodontal ligament (absent/present); loss of lamina dura (absent/present); internal/external root resorption (absent/present).
Eligibility Criteria
Criteria
Inclusion Criteria:
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Patients and parents of the patients who accept to participate and sign the informed consent
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Patients who have at least one vital permanent molar teeth with irreversible pulpitis symptoms
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Teeth which can be restorable after the treatment.
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Teeth which has good periodontal health and in the absence of sinus tracts or swelling.
Exclusion Criteria:
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Patients and parents of the patients who does not accept to participate and sign the informed consent
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Teeth which have dentoalveolar or extraoral swelling
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Teeth which have periodontal disease, mobility or alveolar bone loss
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Teeth which are not restorable
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Patients who are not cooperative with the treatment
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Hacettepe University | Ankara | Turkey | 06100 |
Sponsors and Collaborators
- Hacettepe University
Investigators
- Principal Investigator: Zafer C Cehreli, DDS,PhD, Hacettepe University
Study Documents (Full-Text)
None provided.More Information
Publications
- Asgary S, Eghbal MJ, Ghoddusi J, Yazdani S. One-year results of vital pulp therapy in permanent molars with irreversible pulpitis: an ongoing multicenter, randomized, non-inferiority clinical trial. Clin Oral Investig. 2013 Mar;17(2):431-9. doi: 10.1007/s00784-012-0712-6. Epub 2012 Mar 21.
- Qudeimat MA, Alyahya A, Hasan AA. Mineral trioxide aggregate pulpotomy for permanent molars with clinical signs indicative of irreversible pulpitis: a preliminary study. Int Endod J. 2017 Feb;50(2):126-134. doi: 10.1111/iej.12614. Epub 2016 Feb 22.
- Taha NA, Ahmad MB, Ghanim A. Assessment of Mineral Trioxide Aggregate pulpotomy in mature permanent teeth with carious exposures. Int Endod J. 2017 Feb;50(2):117-125. doi: 10.1111/iej.12605. Epub 2016 Jan 30.
- Irreversible pulpitis