LA-COVID: Description of a Cohort of Covid-19 Patients With a Circulating Anticoagulant
Study Details
Study Description
Brief Summary
SARS-COV-2 infection is responsible for a potentially severe primarily respiratory infection called COVID19. A large proportion of patients, in particular in severe forms, present with thrombotic manifestations (DVT, EP, stroke, thrombosis of dialysis circuits, etc.). A significant proportion is also a carrier of circulating anticoagulant (ACC or LA), making it possible to suggest a diagnosis of APS. This type of autoantibody results in a spontaneous prolongation of the TCA uncorrected by a control serum therefore is quickly diagnosed using standard hemostasis The objective of this study is to describe the diagnosis of thrombotic complications in COVID19 patients presenting a positive lupus anticoagulant type test (LA) or aPL and the associated clinical and biological elements that may have favored thrombosis.
Condition or Disease | Intervention/Treatment | Phase |
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Study Design
Outcome Measures
Primary Outcome Measures
- Retrospective study of thrombotic complications in a cohort of COVID patients with a circulating anticoagulant [Files analysed retrospectively from March 01, 2020 to May 31, 2019 will be examined]]
Eligibility Criteria
Criteria
Inclusion criteria:
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Adult patient (≥18 years old)
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Patient taken care of in the SMO pole or the NHC surgical resuscitation service or hospitalized or consultant to the HUS between 01/03/2020 and 31/05/2020
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Patient infected with Covid-19, with a documented infection, having presented a documented thrombosis (arterial or venous), with an LA or aPL in the thrombosis assessment
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or Patient infected with Covid-19, with a documented infection, without documented thrombosis (arterial or venous), with in the standard work-up an increase in TCA revealing the presence of LA
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Subject having given his agreement for the reuse of his data for the purposes of this research
Exclusion criteria:
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Subject having expressed opposition to participating in the study
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Subject under guardianship or guardianship
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Subject under safeguard of justice
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Service de Médecine Interne et d'Immunologie Clinique - Hôpitaux Universitaires de Strasbourg | Strasbourg | France | 67091 |
Sponsors and Collaborators
- University Hospital, Strasbourg, France
Investigators
- Principal Investigator: Anne-Sophie Korganow, MD, PhD, Service de Médecine Interne et d'Immunologie Clinique - Hôpitaux Universitaires de Strasbourg
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 7861