Calci-DT: Diagnostic Performance of Coronary Calcification Detection on CT Scan

Sponsor
University Hospital, Strasbourg, France (Other)
Overall Status
Recruiting
CT.gov ID
NCT05538117
Collaborator
(none)
300
1
14
21.4

Study Details

Study Description

Brief Summary

thoracic pain is one of the most frequent reasons for consulting the emergency room. Chest pain can be a sign of different pathologies with a wide range of severity, from life-threatening aortic dissection or myocardial infarction to chest pain during an anxiety attack. Efficient triage of patients is therefore a crucial issue for emergency physicians in order not to ignore an acute coronary event requiring early and specific management.

The investigators seek to evaluate whether a diagnostic strategy based on a thoracic CT scan to rule out coronary calcifications and a single troponin assay can exclude an acute coronary event with sufficient accuracy compared to usual management.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    300 participants
    Observational Model:
    Case-Only
    Time Perspective:
    Retrospective
    Official Title:
    Diagnostic Performance of Coronary Calcification Detection on CT Scan for the Management of Patients Consulting for the Diagnosis of Acute Coronary Events in Patients Presenting With Low- or Intermediate-risk Chest Pain to the Emergency Department
    Actual Study Start Date :
    Aug 18, 2022
    Anticipated Primary Completion Date :
    Oct 1, 2023
    Anticipated Study Completion Date :
    Oct 18, 2023

    Outcome Measures

    Primary Outcome Measures

    1. Ability of scan CT to detect coronary calcifications in patients presenting with thoracic pain to the emergency department [Presence on the scanner of calcifications 30 minutes after onset of pain]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    All
    Inclusion criteria:
    • Adult patient (≥18 years old)

    • Patient admitted to the emergency room of the Nouvel Hôpital Civil in Strasbourg between 06/01/2021 and 12/31/2021 and presenting with typical chest pain <30min or atypical symptoms but non-eliminable cardiac origin.

    • Patient with an initial assessment within the norms (ECG not modified, first troponin negative) and having performed a chest CT scan

    • Patient who has not expressed his opposition to the reuse of his data for scientific research purposes.

    Exclusion criteria:
    • Patient who has expressed his opposition to the retrospective reuse of his data for scientific research purposes

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Service d'accueil des urgences - CHU de Strasbourg - France Strasbourg France 67091

    Sponsors and Collaborators

    • University Hospital, Strasbourg, France

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    University Hospital, Strasbourg, France
    ClinicalTrials.gov Identifier:
    NCT05538117
    Other Study ID Numbers:
    • 8697
    First Posted:
    Sep 13, 2022
    Last Update Posted:
    Sep 13, 2022
    Last Verified:
    Sep 1, 2022
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by University Hospital, Strasbourg, France
    Additional relevant MeSH terms:

    Study Results

    No Results Posted as of Sep 13, 2022