TELEPARK: Effect of Remote Cognitive Intervention in Patients With Parkinson's Disease During the COVID-19 Pandemic
Study Details
Study Description
Brief Summary
Retrospective study to evaluate the effect of a remote cognitive-rehabilitative intervention during the Covid outbreak in subjects with Parkinson's disease.
Condition or Disease | Intervention/Treatment | Phase |
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Detailed Description
Mild cognitive impairment is frequent among people with Parkinson's disease. Cognitive training seems effective on cognitive status and for mitigating anxiety and depression. With COVID-19 outbreak, such therapeutic interventions were delivered online. This retrospective study was aimed at evaluating the effectiveness of an online cognitive treatment, carried out in COVID times and based on the Parkinson's-Adapted Cognitive Stimulation Therapy, on cognitive domains and mood in 18 older people with Parkinson's disease.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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Cognitive digital treatment Cognitive digital treatment in patients with Parkinson's disease |
Other: Cognitive digital treatment
The remote cognitive-rehabilitation treatment was based on Parkinson's adapted cognitive stimulation therapy (CST). Fourteen twice-weekly sessions were planned, followed by one session per week for a duration of six months for maintenance therapy. The treatment took place in groups of 4 patients in remote mode through the Microsoft-Teams platform. All subjects maintained the prescribed drug therapy and regular physiotherapy activity during the intervention.
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Outcome Measures
Primary Outcome Measures
- changes in cognitive status [This evaluation was performed in the pre-COVID-19 period, at the beginning of the remote treatment (8 months from the pre-COVID evaluation), and at the end of the remote treatment (7 weeks from the start of the treatment)]
The Mini Mental State Examination (MMSE) was used to evaluate the cognitive status.The test consists of 2 parts: language (time orientation, registration and attention) and performance (recall, response to written/verbal commands, sriting ability and reproduction of complex polygons); the total score can range from 0 to 30, with a higher score indicating better function.
Secondary Outcome Measures
- changes in cognitive domains [This evaluation was performed in the pre-COVID-19 period, at the beginning of the remote treatment (8 months from the pre-COVID evaluation), and at the end of the remote treatment (7 weeks from the start of the treatment)]
The Addembrooke's Cognitive Examination Battery (ACE-R) was used to evaluate the cognitive domains. The ACE-R consists of six components evaluating separate cognitive domains. A maximum score of 100 is weighted as follows: orientation (10), attention (8), memory(35), verbal fluency (14), language (28), and visuospatialability (5).
- changes in thymic state [This evaluation was performed in the pre-COVID-19 period, at the beginning of the remote treatment (8 months from the pre-COVID evaluation), and at the end of the remote treatment (7 weeks from the start of the treatment)]
The Geriatric Depression Scale-15 items (GDS-15 items) was used to evaluate the tymic state.This instrument evaluated depressive symptoms using yes/no answers. Scores range between 0 and 15 points. Higher scores indicate more severe depressive symptoms.
Eligibility Criteria
Criteria
Inclusion Criteria:
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Parkinson disease: Hoehn & Yahr's scale: 1-3 based on the UK PD Society Brain Bank
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mild cognitive impairment
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no cognitive training between March and October 2020
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presence of a family caregiver to access and use the online platform
Exclusion Criteria:
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other neurological diseases
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deep brain stimulation
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schizophrenia
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depression
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sensory deprivations that could interfere with the treatment
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | IRCCS INRCA Hospital | Ancona | Italy | 60127 |
Sponsors and Collaborators
- Istituto Nazionale di Ricovero e Cura per Anziani
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- INRCA_004_2022