Effect of Different Ultrasound Doses on Median Nerve Conduction Parameters
Study Details
Study Description
Brief Summary
The current study investigates the effect of different doses of pulses ultrasound therapy on different nerve conduction parameters of the median nerve in healthy volunteering subjects.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
N/A |
Detailed Description
In the current study, we apply pulsed ultrasound therapy on median nerves of healthy volunteer subjects, at 1 W/cm2 10% duty cycle, 3 W/cm2 10% duty cycle, 1 W/cm2 50% duty cycle, and 3 w/cm2 50% duty cycle. Parameters of median nerve conduction study, Latency, amplitude, area, duration and forearm NCV are recorded before and after application of ultrasound therapy.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Experimental: Low US dose Pulsed US, 1 W/cm2, 10% duty cycle. |
Device: Pulsed Ultrasound Therapy
Ultrasound therapy is applied in the pulsed mode.
|
Experimental: Intermediate US dose Pulsed US, 1 W/cm2, 50% duty cycle. |
Device: Pulsed Ultrasound Therapy
Ultrasound therapy is applied in the pulsed mode.
|
Experimental: High US dose Pulsed US, 3 W/cm2, 10% duty cycle. |
Device: Pulsed Ultrasound Therapy
Ultrasound therapy is applied in the pulsed mode.
|
Experimental: Higher US dose Pulsed US, 3 W/cm2, 50% duty cycle. |
Device: Pulsed Ultrasound Therapy
Ultrasound therapy is applied in the pulsed mode.
|
Outcome Measures
Primary Outcome Measures
- CMAP distal latency [Immediately after application]
msecond
- CMAP amplitude [Immediately after application]
mV
- CMAP duration [Immediately after application]
msecond
- Nerve conduction study [Immediately after application]
m/sec.
Eligibility Criteria
Criteria
Inclusion Criteria:
-
120 hands of 60 subjects of both genders with age range 18: 24 years.
-
Subjects assigned will be apparently healthy subjects with no neurological or neuromuscular history affecting the upper limb.
Exclusion Criteria:
-
Peripheral polyneuropathy.
-
Diabetes mellitus.
-
Previous surgeries or median and/or ulnar nerve release.
-
Cervical radiculopathy.
-
Median or ulnar entrapment neuropathies.
-
Previous or current pregnancies.
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Cairo University
Investigators
- Principal Investigator: Amr S Shalaby, Ph.D., Cairo University
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- REC-43/02/008