The Effect of Acute Concurrent Exercise on Executive Function: An Event-Related Potential Study

Sponsor
National Taiwan Normal University (Other)
Overall Status
Completed
CT.gov ID
NCT05314634
Collaborator
(none)
78
1
3
12
6.5

Study Details

Study Description

Brief Summary

Executive function is a high-level cognition which plays an important role in our life. Meta-analysis study has demonstrated that acute exercise could improve executive function. However, it is still unclear whether executive function can be enhanced by the concurrent exercise that combines aerobic and resistance exercise. Moreover, previous studies indicated that acute exercise could increase the concentration of blood lactate which is positive correlated to executive function. It is still unclear whether the effect of acute concurrent exercise on executive function is mediated by blood lactate. Therefore, the purposes of present study are: (1) Measuring the effect of acute concurrent exercise and aerobic exercise on executive function. (2) Measuring whether the effect of acute concurrent exercise on executive function is mediated by blood lactate.

Condition or Disease Intervention/Treatment Phase
  • Behavioral: concurrent exercise
  • Behavioral: aerobic exercise
N/A

Detailed Description

Executive function is a high-level cognition which plays an important role in academic performance, career, and interpersonal relationship. Meta-analysis study has demonstrated that acute exercise could improve executive function, and also observed similar positive effect through both aerobic and resistance exercise. However, it is still unclear whether executive function can be enhanced by the concurrent exercise that combines aerobic and resistance exercise. Moreover, previous studies indicated that acute exercise could increase the concentration of blood lactate which is positive correlated to executive function. It is still unclear whether the effect of acute concurrent exercise on executive function is mediated by blood lactate. Therefore, the purposes of present study are: (1) Measuring the effect of acute concurrent exercise and aerobic exercise on executive function. (2) Measuring whether the effect of acute concurrent exercise on executive function is mediated by blood lactate.

Study Design

Study Type:
Interventional
Actual Enrollment :
78 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Intervention Model Description:
Participants were randomly assigned to three group, namely the concurrent exercise group (CE), the aerobic exercise group (AE), and the reading control group (RC). Participants in CE groups were asked to finish 5 min warm-up, 12 min aerobic exercise, 13 min resistance exercise, and 5 min cool down. Participants in the AE group were asked to finish 5 min warm-up, 25 min aerobic exercise, and 5 min cool down. Participants in RC group were required to finish 35 min reading. All groups took a 30 min cognitive test before and after the intervention. The blood lactate were collected before, 17 minutes after, and after the intervention.Participants were randomly assigned to three group, namely the concurrent exercise group (CE), the aerobic exercise group (AE), and the reading control group (RC). Participants in CE groups were asked to finish 5 min warm-up, 12 min aerobic exercise, 13 min resistance exercise, and 5 min cool down. Participants in the AE group were asked to finish 5 min warm-up, 25 min aerobic exercise, and 5 min cool down. Participants in RC group were required to finish 35 min reading. All groups took a 30 min cognitive test before and after the intervention. The blood lactate were collected before, 17 minutes after, and after the intervention.
Masking:
None (Open Label)
Primary Purpose:
Treatment
Official Title:
The Effect of Acute Concurrent Exercise on Executive Function: An Event-Related Potential Study
Actual Study Start Date :
Feb 15, 2021
Actual Primary Completion Date :
Aug 15, 2021
Actual Study Completion Date :
Feb 15, 2022

Arms and Interventions

Arm Intervention/Treatment
Experimental: concurrent exercise group, CE

Participants conduct 5-min warm up, 12-min aerobic exercise, 13-min resistance exercise, and 5-min cool down.

Behavioral: concurrent exercise
Participants conduct warm up for 5-min, aerobic exercise for 12-min, resistance exercise for 13-min, and 5-min cool down.

Experimental: aerobic exercise group, AE

Participants conduct 5-min warm up, 25-min aerobic exercise, and 5-min cool down.

Behavioral: aerobic exercise
Participants conduct warm up for 5-min, resistance training for 25-min, and 5-min cool down.

No Intervention: reading control group, RC

Participants conduct reading for 35 minutes.

Outcome Measures

Primary Outcome Measures

  1. stroop test [30 minutes]

    The Stroop task consists of neutral, congruent, and incongruent trials. In neutral trials, colored rectangles were presented and participants were instructed to respond to whether the squares were red, blue, or green. For congruent and incongruent trials, participants were presented with the names of the three Chinese color words of 紅 (red), 藍 (blue), or 綠 (green) printed in either the same (congruent) or different (incongruent) ink color and instructed to respond to the color of the ink while inhibiting the meaning of the word.

Secondary Outcome Measures

  1. task switch test [30 minutes]

    The shifting aspect of executive function was assessed by means of a computer version of the task-switching test. In brief, each participant was presented with six blocks of 64 trials. For the first block, the participant was required to identify whether the stimulus (i.e., digits 1-9, without digit 5) within the solid-line square was greater/less than the digit 5. For the second block, the participant identified whether the stimulus within the dotted-line square was even/odd. The blocks 3-6 consisted of an equal number of stimuli from the first and second blocks forming an alternating-runs paradigm.

Other Outcome Measures

  1. blood lactate [1 minute]

    The lactic acid system is one of the important systems of human energy metabolism. In addition to supplying energy to muscles, it can also be used as an energy source for brain energy metabolism. When people doing exercise, the concentration of blood lactate will be increased, and the lactate acid system will replace the glucose system as the main energy source for the brain. In the present study, blood lactate were collected from fingertip with a lancet and measured by lactate analyzer before, 17 minutes after, and after intervention.

Eligibility Criteria

Criteria

Ages Eligible for Study:
21 Years to 28 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  1. no history of psychiatric or neurological disorders

  2. no history of cardiovascular disease

  3. normal or corrected to normal vision and normal color perception

  4. right handed

  5. 18.5 < BMI < 27

Exclusion Criteria:
  1. Diagnosed with epilepsy

Contacts and Locations

Locations

Site City State Country Postal Code
1 Department of Physical Education and Sport Sciences, National Taiwan Normal University Taipei Taiwan 106

Sponsors and Collaborators

  • National Taiwan Normal University

Investigators

  • Study Director: Yu-Kai Chang, Ph.D., Department of Physical Education and Sport Sciences, National Taiwan Normal University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Yu-Kai Chang, Professor, National Taiwan Normal University
ClinicalTrials.gov Identifier:
NCT05314634
Other Study ID Numbers:
  • PACNL_rueihongli_CE
First Posted:
Apr 6, 2022
Last Update Posted:
Apr 6, 2022
Last Verified:
Mar 1, 2022
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Yu-Kai Chang, Professor, National Taiwan Normal University

Study Results

No Results Posted as of Apr 6, 2022