Fatigue and Kinematics During Isometric Activity of the Upper Limbs in Young and Older Adults

Sponsor
Escola Superior de Saude da Cruz Vermelha Portuguesa - Lisboa (Other)
Overall Status
Completed
CT.gov ID
NCT04938791
Collaborator
(none)
60
1
1
4.9
12.2

Study Details

Study Description

Brief Summary

The aim of this study is to understand the relationship between perceived effort and physiological and kinematic variables caused by isometric activity of the upper limbs, as well as its relationship with socio-demographic characteristics, level of activity and quality of life.

Condition or Disease Intervention/Treatment Phase
  • Other: Isometric activity
N/A

Study Design

Study Type:
Interventional
Actual Enrollment :
60 participants
Allocation:
N/A
Intervention Model:
Single Group Assignment
Masking:
None (Open Label)
Primary Purpose:
Basic Science
Official Title:
Relationship Between Perceive Effort, Physiological and Kinematic Changes During Upper Limbs Isometric Activity and Its Relationship With the Socio-demographic Characteristics
Actual Study Start Date :
Oct 1, 2021
Actual Primary Completion Date :
Feb 28, 2022
Actual Study Completion Date :
Feb 28, 2022

Arms and Interventions

Arm Intervention/Treatment
Experimental: Isometric activity

All participants will be included in this arm

Other: Isometric activity
Participants will do elevation of upper limbs and mantain a 90º degree flexion position in an unsupported way.
Other Names:
  • Isometric task
  • Outcome Measures

    Primary Outcome Measures

    1. Change from Baseline in perceived effort on the Borg category-ratio 10-point scale (CR 10) [From baseline to end of activity, up to 15 minutes]

      The perceived effort will be measured with Borg CR 10 scale. Possible scores range from 0 (no exertion at all) to 10 (extremely strong).

    2. Change from Baseline in heart rate [From baseline to end of activity, up to 15 minutes]

      Heart rate (heart beatings per minute) measured before and during activity to track cardiovascular changes during activity.

    3. Change from Baseline in respiratory rate [From baseline to end of activity, up to 15 minutes]

      Respiratory rate (respiratory cycles per minute) measured before and during activity to track changes in respiratory function during activity.

    4. Change from Baseline in heart rate variability (HRV) [From baseline to end of activity, up to 15 minutes]

      Interval (in milliseconds) between consecutive heartbeats measured before and during activity to track changes in autonomic function during activity.

    5. Change from Baseline in electrodermal activity (EDA) [From baseline to end of activity, up to 15 minutes]

      Electrical conductance (in microsiemens -µS) between two points of the hand over time measured before and during activity to track changes in autonomic function during activity.

    6. Change from Baseline in muscle action potential amplitude through surface electromyography (sEMG) [From baseline to end of activity, up to 15 minutes]

      Muscle action potential amplitude (in millivolts - ms) in surface electromyographic signal measured before and during activity to track muscular fatigue signs.

    7. Change from Baseline in muscle action potential duration through surface electromyography (sEMG) [From baseline to end of activity, up to 15 minutes]

      Muscle action potential duration (in milliseconds - ms) in surface electromyographic signal measured before and during activity to track muscular fatigue signs.

    8. Change from Baseline in muscle action potential frequency through surface electromyography (sEMG) [From baseline to end of activity, up to 15 minutes]

      Muscle action potential frequency (in hertz - Hz) of surface electromyographic signal measured before and during activity to track muscular fatigue signs.

    9. Change from Baseline in respiratory pattern through inertial motion units (IMU) from baseline and during activity [From baseline to end of activity, up to 15 minutes]

      Angular range of motion (in degrees) of rib cage and abdominal wall during upper limb activity measured before and during activity to track changes in respiratory pattern during activity

    10. Change from Baseline in upper limb motion angular acceleration through inertial motion units (IMU) system [From baseline to end of activity, up to 15 minutes]

      Angular acceleration (in m/s^2) of the arm measured before and during activity to track small movements of upper limb during isometric activity

    Secondary Outcome Measures

    1. Health Status [Before isometric activity]

      Health Status will be measured with Medical Outcomes Study (MOS) Short Form Health Survey 36 Item version 2 which measure health status of populations and individuals. Possible scores range from 0 0 (worst health status) to 100 (best health status).

    2. Physical activity level [Before isometric activity]

      Physical activity level will be measured using European Prospective Investigation into Cancer and Nutrition Physical Activity Questionnaire (EPIC-PAQ) that allows to estimate energy expenditure through self-report assessment of the intensity and average duration (per day, week and month) of physical activity performed by the participants in three distinct dimensions (professional, domestic and leisure). Participants are classified as ACTIVE if they perform: at least 150 minutes per week of moderate physical activity; OR at least 75 minutes per week of vigorous physical activity; OR at least 150 minutes per week of a combination of moderate-intensity activity. If they don't present any of the conditions described, they will be categorized as SEDENTARY.

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:
    • Healthy

    • Minimum age of 18 years;

    Exclusion Criteria:
    • Unable to provide written consent

    • History of heart, cardiovascular and / or respiratory disease,

    • Known untreated hypertension, cardiomyopathy, or exercise intolerance

    • Presence of cognitive or neurological disorders

    • Neuromuscular or orthopaedic disorder that limits the movement of the upper limb to 90° flexion or the maintenance of that position

    • BMI ≥ 40

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Escola Superior de Saúde da Cruz Vermelha Portuguesa - Lisboa Lisboa Portugal 1300-125

    Sponsors and Collaborators

    • Escola Superior de Saude da Cruz Vermelha Portuguesa - Lisboa

    Investigators

    • Study Director: Daniel López López, PhD, Universidade da Coruña

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Helena Silva, Associate Senior Professor, Escola Superior de Saude da Cruz Vermelha Portuguesa - Lisboa
    ClinicalTrials.gov Identifier:
    NCT04938791
    Other Study ID Numbers:
    • ESSCVP_FIS01/2021
    First Posted:
    Jun 24, 2021
    Last Update Posted:
    Mar 31, 2022
    Last Verified:
    Mar 1, 2022
    Individual Participant Data (IPD) Sharing Statement:
    No
    Plan to Share IPD:
    No
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by Helena Silva, Associate Senior Professor, Escola Superior de Saude da Cruz Vermelha Portuguesa - Lisboa
    Additional relevant MeSH terms:

    Study Results

    No Results Posted as of Mar 31, 2022