Health System Dynamic & Resource Requirement in a South African COVID-19 Field Hospital

Sponsor

University of Cape Town (Other)

Overall Status

Completed

CT.gov ID

NCT05113875

Collaborator

(none)

596

Enrollment

Location

1.6

Actual Duration (Months)

377.9

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The aim of this study is to describe the patient clinical profile, resource requirements, and health system dynamics in a field hospital during the second wave of the Coronavirus (COVID-19) pandemic, leading to the outbreak of viral severe acute respiratory syndrome (SARS-CoV-2 virus), in South Africa. By describing the field hospital in this unique setting, the investigators hope to provide an efficient guide to similar settings across low- and middle-income countries.

This was a retrospective, single-center study. A total of 596 patients with confirmed COVID-19 were admitted to Mitchells Plain Hospital of Hope (MPHOH), Cape Town, South Africa, between January 1st and February 28th, 2021. Patient clinical characteristics, outcome, and resource allocation was collected. Daily hospital dynamics, including admissions, discharges, deaths and oxygen use was analyzed and compared to the local and national COVID-19 incidence rates.

Condition or Disease	Intervention/Treatment	Phase
Field Hospitals COVID-19 Pandemic Health Systems Global Health Health Resources Low-Income Population

Detailed Description

The aim of the study is to amplify what is known about field hospitals in resource-constrained setting, so as to guide meaningfully the future COVID-19 public health response. Understanding not only the patient profile, but clinical resource requirements, and health system dynamic in a South African field hospital during the second wave of the COVID-19 pandemic can help in preparation for a future infection surge. This will shed light on the extent and timing of excess demand for intermediate care facilities for COVID-19 during peak infection periods in this region. Furthermore, lessons learnt here can guide efforts in similar settings across low-and middle-income countries.

Data was collected on all patients admitted to MPHOH between January 1st and February 28th 2021 using notes from patient folders' and an electronic hospital records systems. Patient demographics, clinical profile, resource utilization; as well as the hospital dynamics were collected. COVID-19 incidence rates were collected from the National Institute for Infectious Diseases, South Africa

A descriptive data analysis was performed to report the number, mean, median, and range of all relevant values. Hospital level data were summarized into weekly intervals, described and compared to COVID-19 incidence rates. Statistical data analysis was performed using R Statistical Computing program and Microsoft Excel.

Study Design

Study Type:

Observational [Patient Registry]

Actual Enrollment :

596 participants

Observational Model:

Case-Only

Time Perspective:

Cross-Sectional

Official Title:

Health System Dynamic & Resource Requirement in a South African COVID-19 Field

Actual Study Start Date :

Feb 11, 2021

Actual Primary Completion Date :

Mar 31, 2021

Actual Study Completion Date :

Mar 31, 2021

Arms and Interventions

Arm	Intervention/Treatment
COVID-19 Patients Completed Sample of all patients admitted to the Mitchells Plain Hospital of Hope COVID-19 Field Hospital between January 1st and February 29th 2021. All patients were diagnosed with COVID-19 prior to admission to the hospital and were transferred directly from a referring hospital.

Outcome Measures

Primary Outcome Measures

Patient Demographics [January 1st to February 29th 2021]
Patient age (in numbers)
Patient Demographics [January 1st to February 29th 2021]
Patient sex (male or female)
Patient Clinical Condition [January 1st to February 29th 2021]
Patient medical comorbidities on admission (categorical)
Patient Clinical Condition [January 1st to February 29th 2021]
If patient diabetic, type of diabetic treatment received in hospital (oral vs insulin therapy)
Patient Clinical Condition [January 1st to February 29th 2021]
If patient diabetic, glycated haemoglobin (HBA1C) level during admission (in numbers)
Patient Clinical Condition [January 1st to February 29th 2021]
Patient clinical complications during hospital admission (categorical)
Patient Clinical Condition [January 1st to February 29th 2021]
If patient received antibiotic treatment during admission, name of infection treated (categorical)
Patient Clinical condition [January 1st to February 29th 2021]
Patient ICU priority triage score on admission (in numbers)
Hospital Human Resources Utilized [January 1st to February 29th 2021]
Number of patients who utilized palliative care services (in numbers)
Hospital Human Resources Utilized [January 1st to February 29th 2021]
Number of patients who utilized dietician services (in numbers)
Hospital Human Resources Utilized [January 1st to February 29th 2021]
Number of patients who utilized physiotherapy services (in numbers)
Hospital Physical Resources Utilized [January 1st to February 29th 2021]
Number of patients requiring oxygen therapy during admission (in numbers)
Hospital Physical Resources Utilized [January 1st to February 29th 2021]
Type of oxygen therapy utilized by each patient (Categorical: nasal prong oxygen; face mask oxygen; or high flow oxygen)
Hospital Physical Resources Utilized [January 1st to February 29th 2021]
Duration of oxygen therapy for each patient (in days)
Hospital Physical Resources Utilized [January 1st to February 29th 2021]
Number of patients requiring antibiotic treatment (in numbers)
Hospital Physical Resources Utilized [January 1st to February 29th 2021]
If patient required antibiotic therapy, name of antibiotic given (categorical)
Hospital Physical resources Utilized [January 1st to February 29th 2021]
Patient duration of hospital stay (in days)
Health System Dynamics [January 1st to February 29th 2021]
Daily number of patients admitted to hospital (in numbers/day)
Health System Dynamics [January 1st to February 29th 2021]
Daily number of inpatients at hospital (in numbers/day)
Health System Dynamics [January 1st to February 29th 2021]
Daily number of patients discharged from hospital (in numbers/day)
Health System Dynamics [January 1st to February 29th 2021]
Daily number of patient deaths (in numbers/day)
Health System Dynamics [January 1st to February 29th 2021]
Daily number of patients transferred out of hospital to another medical facility (in numbers/day)
Health System Dynamics [January 1st to February 29th 2021]
Daily hospital bed capacity (in numbers/day)
Health System Dynamics [January 1st to February 29th 2021]
Daily hospital oxygen consumption (in kg/day)
Health System Dynamics [January 1st to February 29th 2021]
Name of hospital from which each patient was referred from (categorical)
Local Incidence rates of COVID-19 infections [December 1st 2020 to February 29th 2021]
South African National COVID-19 incidence rates per week (in numbers/week)
Local Incidence rates of COVID-19 infections [December 1st 2020 to February 29th 2021]
Western Cape Provincial COVID-19 incidence rates per week (in numbers/week)

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

All patients admitted to the Mitchells Plain Hospital of Hope COVID-19 field hospital between 1st January 2021 and 29th February 2021. Patients admitted to the hospital must have been: over 18years of age, diagnosed with COVID-19 via polymerase chain reaction (PCR) test, transferred from a referring facility.

Exclusion Criteria:

No patients were excluded.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Mitchells Plain Hospital of Hope Covid-19 Field Hospital, Lentegeur Hospital	Cape Town	Western Province	South Africa	7785

Sponsors and Collaborators

University of Cape Town

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Ruth Verity Passchier, Doctor, University of Cape Town

ClinicalTrials.gov Identifier:

NCT05113875

Other Study ID Numbers:

African Covid19 Field Hospital

First Posted:

Nov 9, 2021

Last Update Posted:

Nov 9, 2021

Last Verified:

Nov 1, 2021

Individual Participant Data (IPD) Sharing Statement:

Plan to Share IPD:

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Additional relevant MeSH terms:

COVID-19

Study Results

No Results Posted as of Nov 9, 2021