I2 and thyroid: Frequency of Florid Hyperthyroidism In Patients Taking Iodinated Salt

Sponsor

Services Institute of Medical Sciences, Pakistan (Other)

Overall Status

Not yet recruiting

CT.gov ID

NCT04809454

Collaborator

(none)

100

Enrollment

Location

Anticipated Duration (Months)

20.2

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Thyroxin a vital hormone for life lot of body functions depend on proper functioning on pituitary thyroid axis. it exists in two major forms Thyroxine (T4) and (T3) , each of them containing two iodine atoms on their inner (tyrosine) ring. Synthesis of reasonable quantities of thyroid hormones requires adequate iodine intake to allow sufficient thyroidal uptake. The World Health Organization (WHO) recommendation for daily intake of iodine is 150 μg for children ≥12 years and adults, and 250 μg for pregnant and lactating women. However as we know optimum amount of iodine is required for normal pituitary thyroid axis like wise excessive intake may cause over functioning of axis hence over production of hormone that can be manifested both clinically and biochemically.

This study is designed to observe the frequency of over hyperthyroidism in patients taking iodinated salt.

Condition or Disease	Intervention/Treatment	Phase
Thyroid Dysfunction

Detailed Description

All patients presenting to endocrine clinic fulfilling inclusion and exclusion criteria will be recruited. They will be examined, their vitals including blood pressure pulse will be noted, thyroid clinical examination including eye signs and thyroid status will be done biochemical Thyroid profile (TSH, Free T3 & Free T4) will be noted in predesigned proforma.

Statistical Analysis will be done ,after data is entered in Statistical Package for the Social Sciences (SPSS) version 25 .qualitative data will be presented as frequencies and percentages while quantitative data will be presented as mean medians and standard deviations.

Study Design

Study Type:

Observational

Anticipated Enrollment :

100 participants

Observational Model:

Other

Time Perspective:

Cross-Sectional

Official Title:

Frequency of Florid Hyperthyroidism In Patients Taking Iodinated Salt: A Cross Sectional Study

Anticipated Study Start Date :

Oct 1, 2021

Anticipated Primary Completion Date :

Mar 1, 2022

Anticipated Study Completion Date :

Mar 1, 2022

Outcome Measures

Primary Outcome Measures

Affect of Iodinated Salt on Thyroid Status [through study completion an average of 12 weeks]
Affect of Iodinated Salt on Thyroid Status

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years to 60 Years

Sexes Eligible for Study:

All

Inclusion Criteria:

All patients presenting with biochemical hyperthyroidism
Who are taking Iodinated salt.
Treatment naïve patients
Both genders included
All patients who can give consent (18-60 years)

Exclusion Criteria:

Pregnant females 2) Lactating mothers

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Mehwish Iftikhar	Lahore	Punjab	Pakistan	54000

Sponsors and Collaborators

Services Institute of Medical Sciences, Pakistan

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Mehwish Iftikhar, Principal Investigator, Services Institute of Medical Sciences, Pakistan

ClinicalTrials.gov Identifier:

NCT04809454

Other Study ID Numbers:

1241985

First Posted:

Mar 22, 2021

Last Update Posted:

Sep 22, 2021

Last Verified:

Sep 1, 2021

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Keywords provided by Mehwish Iftikhar, Principal Investigator, Services Institute of Medical Sciences, Pakistan

Thyroid

Iodine

Additional relevant MeSH terms:

Hyperthyroidism

Study Results

No Results Posted as of Sep 22, 2021