Gait Parameters and Balance in Patients With Obstructive Lung Diseases

Sponsor
Hacettepe University (Other)
Overall Status
Recruiting
CT.gov ID
NCT04062292
Collaborator
(none)
15
1
14.3
1

Study Details

Study Description

Brief Summary

In the literature, most of the studies examining the gait characteristics and balance separately or examining the relationship between them are on patients with COPD.

No study examining gait parameters in other obstructive pulmonary patients such as bronchiectasis and asthma was found.A convincing link between gait disturbances and falls in COPD patients is still unknown and further research is needed. Therefore, the purpose of our study; gait parameters and balance in individuals with obstructive pulmonary disease. We will also examine the relationship between gait parameters and extrapulmonary clinical indicators of these individuals.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    Patients with COPD call walking as one of the most problematic activities in daily life. Patients with COPD walk less in daily life than their healthy peers. Gait characteristics of extrapulmonary comorbidities that probably affect the musculoskeletal and cardiovascular system vary. The gait assessment gives an idea about the biomechanical factors associated with a reduction in walking distance in COPD patients. In patients with COPD, after the onset of shortness of breath or leg fatigue, a decrease in cadence during walking, shortened stride length, an increase in the time spent in the double support period, an increase in the peak ankle dorsi flexion moment is observed. During gait, there is an increase in balance disorders in the mediolateral direction. In addition, patients with COPD walk on a constant speed treadmill with more stride time and less step width variability. Studies have shown that patients with COPD have increased temporal walking characteristics, decreased step and stride length, and increased walking variability.

    In the literature, most of the studies that examine gait characteristics and balance separately or examine the relationship between them are on patients with COPD. No study examining gait parameters in other obstructive pulmonary patients such as bronchiectasis and asthma has been found. A persuasive link between walking disorders and falls in COPD patients is still unknown and further research is needed. This study will contribute to clarifying the mechanisms of why the balance studied in patients with COPD is adversely affected.

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    15 participants
    Observational Model:
    Case-Control
    Time Perspective:
    Prospective
    Official Title:
    Investigation of Gait Parameters and Balance in Patients With Obstructive Lung Diseases
    Actual Study Start Date :
    Jan 29, 2021
    Anticipated Primary Completion Date :
    Mar 30, 2022
    Anticipated Study Completion Date :
    Apr 10, 2022

    Arms and Interventions

    Arm Intervention/Treatment
    Obstructive lung diseases group

    Having been diagnosed with obstructive pulmonary disease, No acute exacerbation or infection in the past 1 week, Being between the ages of 18 and 65,

    Healthy group

    Age and sex matched healthy subjects without orthopedic and chronic diseases

    Outcome Measures

    Primary Outcome Measures

    1. Gait parameters [01.09.2020-08.07.2021]

      Gait parameters will be assessed with Biodex Gait Trainer (Biodex Medical Systems, Shirley, New York) for six minutes.

    Secondary Outcome Measures

    1. Functional Balance and Fall Risk [01.09.2020-08.07.2021]

      Timed Up and Go Test

    2. Functional Exercise Capacity [01.09.2020-08.07.2021]

      6 minute walking test

    3. Respiratory Muscle Strength [01.09.2020-08.07.2021]

      Respiratory muscle strength parameters (maximal inspiratory and maximal expiratory pressure) measurement using mouth pressure device

    4. Peripheral Muscle Strength [01.09.2020-08.07.2021]

      Muscle strength of the knee extensors, hip extensors, shoulder abductors, trunk flexors and trunk extensors will be evaluated by hand dynamometer (Lafayette Manual Muscle Tester Model 01165-USA). Jamar Hand Dynamometer (USA) will measure the hand grip force

    5. Activities of Daily Living [01.09.2020-08.07.2021]

      Glittre-ADL test

    6. Cognitive Status [01.09.2020-08.07.2021]

      Mini Mental Test

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years to 65 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes

    Inclusion Criteria for Obstructive Lung Diseases

    1. Being diagnosed with obstructive lung disease,

    2. Have not experienced acute exacerbation or infection in the last 1 week,

    3. To be between 18-65 years,

    4. Volunteering for research,

    5. To be able to walk and cooperate.

    Exclusion Criteria for Obstructive Lung Diseases:
    1. Use walking aid or be chronic oxygen support

    2. To have orthopedic or neuromuscular comorbidities that may affect walking patterns.

    3. Having had lung cancer, sarcoidosis, tuberculosis disease or lung surgery.

    Inclusion Criteria for Healthy People 1.18-65 years of age, 2. Volunteer to participate in the research, 3. To be able to walk and cooperate.

    Exclusion Criteria for Healthy People

    1. Having any cardiopulmonary disease,

    2. To have an advanced orthopedic disease that may affect functional capacity measurement and gait patterns.

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Naciye Vardar-Yagli Ankara Turkey 06100

    Sponsors and Collaborators

    • Hacettepe University

    Investigators

    • Principal Investigator: Naciye Vardar-Yagli, PhD, Hacettepe University

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Naciye Vardar-Yagli, Associate Professor, Hacettepe University
    ClinicalTrials.gov Identifier:
    NCT04062292
    Other Study ID Numbers:
    • GO 19/665
    First Posted:
    Aug 20, 2019
    Last Update Posted:
    Jan 18, 2022
    Last Verified:
    Jan 1, 2022
    Individual Participant Data (IPD) Sharing Statement:
    No
    Plan to Share IPD:
    No
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by Naciye Vardar-Yagli, Associate Professor, Hacettepe University
    Additional relevant MeSH terms:

    Study Results

    No Results Posted as of Jan 18, 2022