GREAT: Gathering Records to Evaluate Antiretroviral Treatment-South Africa
Study Details
Study Description
Brief Summary
To achieve global goals for the treatment of HIV, most high-prevalence countries are experimenting with and scaling up differentiated service delivery models (DSD). A handful of efforts have been formally described and evaluated in the literature; many others are being implemented formally or informally under routine care, without a research or evaluation goal. For most countries, however, we have little evidence on the big picture-the proportion of clinics offering alternative models, eligibility criteria and the proportion of patients considered eligible, the number of patients actually participating, health outcomes such as viral suppression, empirical resource utilization compared to traditional care, variations among the models, duration of patient participation, fidelity to model guidelines, effects on clinic efficiency, and sustainability without external donor support.
AMBIT a set of data synthesis, data collection, and data analysis activities aimed at generating information for near- and long-term decision making and creating an approach and platform for ongoing evaluation of differentiated models of HIV treatment delivery in the future. The project will collect and analyze a wide range of existing data sets pertinent to DSD. This protocol is for an analysis of existing medical record data collected by the Department of Health, implementing partners, and other completed, ongoing, or new evaluations, trials, and observational studies. Outcomes to be reported include coverage/uptake of DSD, patients' outcomes, and distribution of each model. There will be no study interaction with individual patients, providers, caregivers, or others for this analysis.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Patients enrolled in differentiated service delivery models
|
Other: Routine medical record data collection
The study will collect routine medical record data from the electronic medical record system, other electronic databases, and paper charts.
|
| Patients not enrolled in DSD models
|
Other: Routine medical record data collection
The study will collect routine medical record data from the electronic medical record system, other electronic databases, and paper charts.
|
Outcome Measures
Primary Outcome Measures
- Patient-months enrolled in any DSD model [12 months]
% of all patient-months of ART provided for the cohort that are provided within DSD models
- Patient-months enrolled in any DSD model [24 months]
% of all patient-months of ART provided for the cohort that are provided within DSD models
- Patient-months enrolled in any DSD model [6 months]
% of all patient-months of ART provided for the cohort that are provided within DSD models
Eligibility Criteria
Criteria
Inclusion Criteria:
-
≥ 15 years old
-
Patients accessing care for HIV within the data collection period
-
In any HIV transmission risk group
Exclusion Criteria:
- None
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | All clinics | Johannesburg | South Africa | 2193 |
Sponsors and Collaborators
- Boston University
- Bill and Melinda Gates Foundation
- University of Witwatersrand, South Africa
Investigators
- Principal Investigator: Sydney Rosen, Boston University
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- H-38815