Glaucoma After Congenital Cataract Surgery
Study Details
Study Description
Brief Summary
To determine the incidence of glaucoma following bilateral congenital cataract removal and estimate the associated risk factors in a large cohort to provide guidance for clinical practice.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
Detailed Description
A prospective longitudinal cohort study of pediatric patients who underwent surgery for congenital/infantile cataracts between January 2011 and December 2025 was performed.
Study Design
Outcome Measures
Primary Outcome Measures
- the incidence of glaucoma after congenital cataract surgery [baseline]
A Kaplan-Meier analysis was used
Secondary Outcome Measures
- Risk factors of glaucoma after congenital cataract surgery [baseline]
Piecewise exponential survival models with mixed effects (PEWSMME) were used.(variables including demographic characters, surgery categories, clinical history, length of follow up).
Eligibility Criteria
Criteria
Inclusion Criteria:
-
a diagnosis of bilateral congenital cataracts, the etiologies include congenital idiopathic cataract and congenital cataract associated with a systemic syndrome or ocular anomalies;
-
cataract surgery performed in ZOC;
-
age at cataract removal younger than 16 years;
Exclusion Criteria:
-
the preoperative IOP was above 21 mm Hg;
-
family history of glaucoma;
-
signs of preoperative glaucoma were present, such as corneal clouding, corneal enlargement, excessive cup-disc ratio and myopic shift;
-
ocular trauma history;
-
previous surgery intervention and
-
they were noncompliant with our follow-up protocol to monitor the occurrence of glaucoma and glaucoma suspect.
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | Zhongshan Ophthalmic Center, Sun Yat-sen Univerisity | Guangzhou | Guangdong | China | 510000 |
Sponsors and Collaborators
- Sun Yat-sen University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- CCPMOH2020