GOUTMETALSAIN: Comparison of the Perception of Metallic Taste According to Lingual Locations in Healthy Volunteers

• Sponsor: Centre Hospitalier de Valence (Other)
• Overall Status: Completed
• CT.gov ID: NCT05227157
• Collaborator: (none)
• Enrollment: 60
• Location: 1
• Actual Duration (Months): 4.5
• Patients Per Site Per Month: 13.3

Study Details

Study Description

Brief Summary

This is a mono center , observational study carried out within otorhinolaryngology department in CH Valence.

This is a descriptive and exploratory study in healthy volunteers. Based on the hypothesis that Metallic taste is imperfectly assessed, this study will provide a better understanding of the Metallic Taste.

Condition or Disease	Intervention/Treatment	Phase
Taste Disorders; Sensation Disorders; Taste, Metallic; Taste Disorder, Glossopharyngeal Nerve	Other: swab with iron sulfate solution

Detailed Description

The study consists of the application of a swab soaked in iron sulfate at a concentration of 10g/l.

each patient will rate the intensity he/she perceives (on a numerical scale from 1 to 5) at each of the 4 predefined lingual locations

Study Design

• Study Type: Observational
• Actual Enrollment: 60 participants
• Observational Model: Cohort
• Time Perspective: Prospective
• Official Title: Comparison of the Perception of Metallic Taste According to Lingual Locations in Healthy Volunteers
• Actual Study Start Date: Dec 15, 2021
• Actual Primary Completion Date: Apr 8, 2022
• Actual Study Completion Date: May 1, 2022

Arms and Interventions

Arm	Intervention/Treatment
1: intensity of perception of metallic taste For this study, there is only one arm: swab with iron sulfate solution at a concentration of 10g/l. Each subject complete visual scale	Other: swab with iron sulfate solution; measurement of the intensity of perception of metallic taste by affixing a swab iron sulfate solution 10g/l at 4 places on the tongue depending on the glossopharyngeal nerve: tip of the tongue (right and left); base of the tongue (right and left). Visual analogic Scale (0 to 5)

Outcome Measures

Primary Outcome Measures

1. evaluation of the intensity of metallic taste [5 minutes]

   visual analogue scale (0 to 5); A score of 5 means the highest intensity of metallic taste

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

• Age ≥ 18 years old

• Healthy volunteers

• Read, write and understand the French language

• Patient affiliated to a social security system

• Written and signed informed consent

Exclusion Criteria:

• head and Neck cancer history

• olfactory and gustatory disorder

• Refusal to participate in research

• Patient under guardianship, deprived of liberty, safeguard of justice

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Ch Valence	Valence	Drome	France	26953

Sponsors and Collaborators

• Centre Hospitalier de Valence

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Centre Hospitalier de Valence
• ClinicalTrials.gov Identifier: NCT05227157
• Other Study ID Numbers: 00004
• First Posted: Feb 7, 2022
• Last Update Posted: Jun 9, 2022
• Last Verified: Jun 1, 2022

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Keywords provided by Centre Hospitalier de Valence: Taste, Metallic
• Additional relevant MeSH terms: Taste Disorders; Sensation Disorders; Glossopharyngeal Nerve Diseases; Disease

Study Results

No Results Posted as of Jun 9, 2022